BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

783 related articles for article (PubMed ID: 31071432)

  • 1. The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug for the experimental therapy of sepsis.
    Ahmad A; Vieira JC; de Mello AH; de Lima TM; Ariga SK; Barbeiro DF; Barbeiro HV; Szczesny B; Törö G; Druzhyna N; Randi EB; Marcatti M; Toliver-Kinsky T; Kiss A; Liaudet L; Salomao R; Soriano FG; Szabo C
    Pharmacol Res; 2019 Jul; 145():104263. PubMed ID: 31071432
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of the Poly(ADP-Ribose) Polymerase Inhibitor Olaparib in Cerulein-Induced Pancreatitis.
    Ahmad A; Haas De Mello A; Szczesny B; Törö G; Marcatti M; Druzhyna N; Liaudet L; Tarantini S; Salomao R; Garcia Soriano F; Szabo C
    Shock; 2020 May; 53(5):653-665. PubMed ID: 31274831
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4(+) T cell function.
    Ghonim MA; Pyakurel K; Ibba SV; Al-Khami AA; Wang J; Rodriguez P; Rady HF; El-Bahrawy AH; Lammi MR; Mansy MS; Al-Ghareeb K; Ramsay A; Ochoa A; Naura AS; Boulares AH
    J Transl Med; 2015 Jul; 13():225. PubMed ID: 26169874
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ulinastatin attenuates liver injury and inflammation in a cecal ligation and puncture induced sepsis mouse model.
    Song Y; Miao S; Li Y; Fu H
    J Cell Biochem; 2019 Jan; 120(1):417-424. PubMed ID: 30126034
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The clinically used PARP inhibitor olaparib improves organ function, suppresses inflammatory responses and accelerates wound healing in a murine model of third-degree burn injury.
    Ahmad A; Olah G; Herndon DN; Szabo C
    Br J Pharmacol; 2018 Jan; 175(2):232-245. PubMed ID: 28146604
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacological inhibition of poly (ADP-ribose) polymerase by olaparib, prevents acute lung injury associated cognitive deficits potentially through suppression of inflammatory response.
    Sahu B; Narota A; Naura AS
    Eur J Pharmacol; 2020 Jun; 877():173091. PubMed ID: 32234526
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of tempol, a membrane-permeable radical scavenger, on mesenteric blood flow and organ injury in a murine cecal ligation and puncture model of septic shock.
    Yuksel BC; Serdar SE; Tuncel A; Uzum N; Ataoglu O; Atan A; Hengirmen S; Iskit AB; Guc MO
    Eur Surg Res; 2009; 43(2):219-27. PubMed ID: 19556798
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Olaparib: A Clinically Applied PARP Inhibitor Protects from Experimental Crohn's Disease and Maintains Barrier Integrity by Improving Bioenergetics through Rescuing Glycolysis in Colonic Epithelial Cells.
    Kovács D; Vántus VB; Vámos E; Kálmán N; Schicho R; Gallyas F; Radnai B
    Oxid Med Cell Longev; 2021; 2021():7308897. PubMed ID: 34567413
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of the PARP Inhibitor Olaparib on the Response of Human Peripheral Blood Leukocytes to Bacterial Challenge or Oxidative Stress.
    Santos SS; Brunialti MKC; Rodrigues LOCP; Liberatore AMA; Koh IHJ; Martins V; Soriano FG; Szabo C; Salomão R
    Biomolecules; 2022 Jun; 12(6):. PubMed ID: 35740913
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis.
    Mukhopadhyay P; Horváth B; Rajesh M; Varga ZV; Gariani K; Ryu D; Cao Z; Holovac E; Park O; Zhou Z; Xu MJ; Wang W; Godlewski G; Paloczi J; Nemeth BT; Persidsky Y; Liaudet L; Haskó G; Bai P; Boulares AH; Auwerx J; Gao B; Pacher P
    J Hepatol; 2017 Mar; 66(3):589-600. PubMed ID: 27984176
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice.
    Ghonim MA; Pyakurel K; Ibba SV; Wang J; Rodriguez P; Al-Khami AA; Lammi MR; Kim H; Zea AH; Davis C; Okpechi S; Wyczechowska D; Al-Ghareeb K; Mansy MS; Ochoa A; Naura AS; Boulares AH
    Clin Sci (Lond); 2015 Dec; 129(11):951-62. PubMed ID: 26205779
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Olaparib protects cardiomyocytes against oxidative stress and improves graft contractility during the early phase after heart transplantation in rats.
    Korkmaz-Icöz S; Szczesny B; Marcatti M; Li S; Ruppert M; Lasitschka F; Loganathan S; Szabó C; Szabó G
    Br J Pharmacol; 2018 Jan; 175(2):246-261. PubMed ID: 28806493
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PARP-1 inhibition ameliorates elastase induced lung inflammation and emphysema in mice.
    Dharwal V; Naura AS
    Biochem Pharmacol; 2018 Apr; 150():24-34. PubMed ID: 29355504
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Olaparib attenuates sepsis-induced acute multiple organ injury via ERK-mediated CD14 expression.
    Chen Z; Chen Y; Jin X; Liu Y; Shao Z; Li Q
    Exp Biol Med (Maywood); 2021 Sep; 246(17):1948-1958. PubMed ID: 34053236
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Severity of Cecal Ligature and Puncture-Induced Sepsis Correlates with the Degree of Encephalopathy, but the Sepsis Does Not Lead to Acute Activation of Spleen Lymphocytes in Mice.
    Jeremias IC; Victorino VJ; Machado JL; Barroso WA; Ariga SK; Lima TM; Soriano FG
    Mol Neurobiol; 2016 Jul; 53(5):3389-3399. PubMed ID: 26081155
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dimethyl Fumarate Modulates Oxidative Stress and Inflammation in Organs After Sepsis in Rats.
    Giustina AD; Bonfante S; Zarbato GF; Danielski LG; Mathias K; de Oliveira AN; Garbossa L; Cardoso T; Fileti ME; De Carli RJ; Goldim MP; Barichello T; Petronilho F
    Inflammation; 2018 Feb; 41(1):315-327. PubMed ID: 29124567
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Role of Acetylcholine in the Inflammatory Response in Animals Surviving Sepsis Induced by Cecal Ligation and Puncture.
    Jeremias IC; Victorino VJ; Barbeiro HV; Kubo SA; Prado CM; Lima TM; Soriano FG
    Mol Neurobiol; 2016 Dec; 53(10):6635-6643. PubMed ID: 26637327
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells.
    Min A; Im SA; Kim DK; Song SH; Kim HJ; Lee KH; Kim TY; Han SW; Oh DY; Kim TY; O'Connor MJ; Bang YJ
    Breast Cancer Res; 2015 Mar; 17():33. PubMed ID: 25888415
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rad51 Degradation: Role in Oncolytic Virus-Poly(ADP-Ribose) Polymerase Inhibitor Combination Therapy in Glioblastoma.
    Ning J; Wakimoto H; Peters C; Martuza RL; Rabkin SD
    J Natl Cancer Inst; 2017 Mar; 109(3):1-13. PubMed ID: 28376211
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Senkyunolide I protect against lung injury via inhibiting formation of neutrophil extracellular trap in a murine model of cecal ligation and puncture.
    Zha YF; Xie J; Ding P; Zhu CL; Li P; Zhao ZZ; Li YH; Wang JF
    Int Immunopharmacol; 2021 Oct; 99():107922. PubMed ID: 34224996
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 40.