409 related articles for article (PubMed ID: 31074772)
1. Protective effects of Alda-1, an ALDH2 activator, on alcohol-derived DNA damage in the esophagus of human ALDH2*2 (Glu504Lys) knock-in mice.
Hirohashi K; Ohashi S; Amanuma Y; Nakai Y; Ida T; Baba K; Mitani Y; Mizumoto A; Yamamoto Y; Kikuchi O; Matsubara J; Yamada A; Miyamoto S; Seno H; Matsuda T; Muto M
Carcinogenesis; 2020 Apr; 41(2):194-202. PubMed ID: 31074772
[TBL] [Abstract][Full Text] [Related]
2. Activation of mitochondrial aldehyde dehydrogenase (ALDH2) by ALDA-1 reduces both the acquisition and maintenance of ethanol intake in rats: A dual mechanism?
Rivera-Meza M; Vásquez D; Quintanilla ME; Lagos D; Rojas B; Herrera-Marschitz M; Israel Y
Neuropharmacology; 2019 Mar; 146():175-183. PubMed ID: 30521820
[TBL] [Abstract][Full Text] [Related]
3. ALDH2 dysfunction and alcohol cooperate in cancer stem cell enrichment.
Flashner S; Shimonosono M; Tomita Y; Matsuura N; Ohashi S; Muto M; Klein-Szanto AJ; Alan Diehl J; Chen CH; Mochly-Rosen D; Weinberg KI; Nakagawa H
Carcinogenesis; 2024 Feb; 45(1-2):95-106. PubMed ID: 37978873
[TBL] [Abstract][Full Text] [Related]
4. Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium.
Amanuma Y; Ohashi S; Itatani Y; Tsurumaki M; Matsuda S; Kikuchi O; Nakai Y; Miyamoto S; Oyama T; Kawamoto T; Whelan KA; Nakagawa H; Chiba T; Matsuda T; Muto M
Sci Rep; 2015 Sep; 5():14142. PubMed ID: 26374466
[TBL] [Abstract][Full Text] [Related]
5. Impairment of aldehyde dehydrogenase 2 increases accumulation of acetaldehyde-derived DNA damage in the esophagus after ethanol ingestion.
Yukawa Y; Ohashi S; Amanuma Y; Nakai Y; Tsurumaki M; Kikuchi O; Miyamoto S; Oyama T; Kawamoto T; Chiba T; Matsuda T; Muto M
Am J Cancer Res; 2014; 4(3):279-84. PubMed ID: 24959382
[TBL] [Abstract][Full Text] [Related]
6. Molecular Mechanisms of Acetaldehyde-Mediated Carcinogenesis in Squamous Epithelium.
Mizumoto A; Ohashi S; Hirohashi K; Amanuma Y; Matsuda T; Muto M
Int J Mol Sci; 2017 Sep; 18(9):. PubMed ID: 28891965
[TBL] [Abstract][Full Text] [Related]
7. Cardioprotection induced by a brief exposure to acetaldehyde: role of aldehyde dehydrogenase 2.
Ueta CB; Campos JC; Albuquerque RPE; Lima VM; Disatnik MH; Sanchez AB; Chen CH; de Medeiros MHG; Yang W; Mochly-Rosen D; Ferreira JCB
Cardiovasc Res; 2018 Jun; 114(7):1006-1015. PubMed ID: 29579152
[TBL] [Abstract][Full Text] [Related]
8. Alcohol Intake Interacts with Functional Genetic Polymorphisms of Aldehyde Dehydrogenase (ALDH2) and Alcohol Dehydrogenase (ADH) to Increase Esophageal Squamous Cell Cancer Risk.
Suo C; Yang Y; Yuan Z; Zhang T; Yang X; Qing T; Gao P; Shi L; Fan M; Cheng H; Lu M; Jin L; Chen X; Ye W
J Thorac Oncol; 2019 Apr; 14(4):712-725. PubMed ID: 30639619
[TBL] [Abstract][Full Text] [Related]
9. Pharmacological Activation Of Aldehyde Dehydrogenase 2 Protects Against Heatstroke-Induced Acute Lung Injury by Modulating Oxidative Stress and Endothelial Dysfunction.
Tsai HY; Hsu YJ; Lu CY; Tsai MC; Hung WC; Chen PC; Wang JC; Hsu LA; Yeh YH; Chu P; Tsai SH
Front Immunol; 2021; 12():740562. PubMed ID: 34764958
[TBL] [Abstract][Full Text] [Related]
10. Across-Site Differences in the Mechanism of Alcohol-Induced Digestive Tract Carcinogenesis: An Evaluation by Mediation Analysis.
Koyanagi YN; Suzuki E; Imoto I; Kasugai Y; Oze I; Ugai T; Iwase M; Usui Y; Kawakatsu Y; Sawabe M; Hirayama Y; Tanaka T; Abe T; Ito S; Komori K; Hanai N; Tajika M; Shimizu Y; Niwa Y; Ito H; Matsuo K
Cancer Res; 2020 Apr; 80(7):1601-1610. PubMed ID: 32005715
[TBL] [Abstract][Full Text] [Related]
11. ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA-enriched extracellular vesicles.
Seo W; Gao Y; He Y; Sun J; Xu H; Feng D; Park SH; Cho YE; Guillot A; Ren T; Wu R; Wang J; Kim SJ; Hwang S; Liangpunsakul S; Yang Y; Niu J; Gao B
J Hepatol; 2019 Nov; 71(5):1000-1011. PubMed ID: 31279903
[TBL] [Abstract][Full Text] [Related]
12. Novel and prevalent non-East Asian ALDH2 variants; Implications for global susceptibility to aldehydes' toxicity.
Chen CH; Ferreira JCB; Joshi AU; Stevens MC; Li SJ; Hsu JH; Maclean R; Ferreira ND; Cervantes PR; Martinez DD; Barrientos FL; Quintanares GHR; Mochly-Rosen D
EBioMedicine; 2020 May; 55():102753. PubMed ID: 32403082
[TBL] [Abstract][Full Text] [Related]
13. Targeting liver aldehyde dehydrogenase-2 prevents heavy but not moderate alcohol drinking.
Guillot A; Ren T; Jourdan T; Pawlosky RJ; Han E; Kim SJ; Zhang L; Koob GF; Gao B
Proc Natl Acad Sci U S A; 2019 Dec; 116(51):25974-25981. PubMed ID: 31792171
[TBL] [Abstract][Full Text] [Related]
14. Decreased Expression of NRF2 Target Genes after Alcohol Exposure in the Background Esophageal Mucosa of Patients with Esophageal Squamous Cell Carcinoma.
Toda S; Hatta W; Asanuma K; Asano N; Ono Y; Abe H; Ogata Y; Saito M; Kanno T; Jin X; Uno K; Koike T; Imatani A; Hamada S; Nakamura T; Nakaya N; Masamune A
Tohoku J Exp Med; 2022 Oct; 258(3):195-206. PubMed ID: 36070895
[TBL] [Abstract][Full Text] [Related]
15. Pharmacological activation of aldehyde dehydrogenase 2 by Alda-1 reverses alcohol-induced hepatic steatosis and cell death in mice.
Zhong W; Zhang W; Li Q; Xie G; Sun Q; Sun X; Tan X; Sun X; Jia W; Zhou Z
J Hepatol; 2015 Jun; 62(6):1375-81. PubMed ID: 25543082
[TBL] [Abstract][Full Text] [Related]
16. Combination of ADH1B*2/ALDH2*2 polymorphisms alters acetaldehyde-derived DNA damage in the blood of Japanese alcoholics.
Yukawa Y; Muto M; Hori K; Nagayoshi H; Yokoyama A; Chiba T; Matsuda T
Cancer Sci; 2012 Sep; 103(9):1651-5. PubMed ID: 22703580
[TBL] [Abstract][Full Text] [Related]
17. Increased formation of hepatic N2-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase 2-knockout mice treated with ethanol.
Matsuda T; Matsumoto A; Uchida M; Kanaly RA; Misaki K; Shibutani S; Kawamoto T; Kitagawa K; Nakayama KI; Tomokuni K; Ichiba M
Carcinogenesis; 2007 Nov; 28(11):2363-6. PubMed ID: 17361010
[TBL] [Abstract][Full Text] [Related]
18. Pharmacological recruitment of aldehyde dehydrogenase 3A1 (ALDH3A1) to assist ALDH2 in acetaldehyde and ethanol metabolism in vivo.
Chen CH; Cruz LA; Mochly-Rosen D
Proc Natl Acad Sci U S A; 2015 Mar; 112(10):3074-9. PubMed ID: 25713355
[TBL] [Abstract][Full Text] [Related]
19. Formation of acetaldehyde-derived DNA adducts due to alcohol exposure.
Yu HS; Oyama T; Isse T; Kitagawa K; Pham TT; Tanaka M; Kawamoto T
Chem Biol Interact; 2010 Dec; 188(3):367-75. PubMed ID: 20813101
[TBL] [Abstract][Full Text] [Related]
20. Factors associated with the presence of multiple Lugol-voiding lesions in patients with esophageal squamous-cell carcinoma.
Katada C; Muto M; Tanabe S; Higuchi K; Sasaki T; Azuma M; Ishido K; Katada N; Sakuramoto S; Yamashita K; Masaki T; Nakayama M; Okamoto M; Koizumi W
Dis Esophagus; 2014 Jul; 27(5):457-62. PubMed ID: 23009284
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]