92 related articles for article (PubMed ID: 31076483)
21. Discovery of thiophen-2-ylmethylene bis-dimedone derivatives as novel WRN inhibitors for treating cancers with microsatellite instability.
Yang H; Kang M; Jang S; Baek SY; Kim J; Kim GU; Kim D; Ha J; Kim JS; Jung C; Kim NJ; Cho SY; Shin WH; Lee J; Ko J; Lee A; Keum G; Lee S; Kang T
Bioorg Med Chem; 2024 Feb; 100():117588. PubMed ID: 38295487
[TBL] [Abstract][Full Text] [Related]
22. Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice.
Aumailley L; Garand C; Dubois MJ; Johnson FB; Marette A; Lebel M
PLoS One; 2015; 10(10):e0140292. PubMed ID: 26447695
[TBL] [Abstract][Full Text] [Related]
23. Targeted inhibition of WRN helicase by external guide sequence and RNase P RNA.
Hitrik A; Abboud-Jarrous G; Orlovetskie N; Serruya R; Jarrous N
Biochim Biophys Acta; 2016 Apr; 1859(4):572-80. PubMed ID: 26808708
[TBL] [Abstract][Full Text] [Related]
24. WRN helicase expression in Werner syndrome cell lines.
Moser MJ; Kamath-Loeb AS; Jacob JE; Bennett SE; Oshima J; Monnat RJ
Nucleic Acids Res; 2000 Jan; 28(2):648-54. PubMed ID: 10606667
[TBL] [Abstract][Full Text] [Related]
25. Analysis of microsatellite instability in CRISPR/Cas9 editing mice.
Huo X; Du Y; Lu J; Guo M; Li Z; Zhang S; Li X; Chen Z; Du X
Mutat Res; 2017 Mar; 797-799():1-6. PubMed ID: 28284774
[TBL] [Abstract][Full Text] [Related]
26. Lack of WRN results in extensive deletion at nonhomologous joining ends.
Oshima J; Huang S; Pae C; Campisi J; Schiestl RH
Cancer Res; 2002 Jan; 62(2):547-51. PubMed ID: 11809708
[TBL] [Abstract][Full Text] [Related]
27. Role for the Werner syndrome protein in the promotion of tumor cell growth.
Opresko PL; Calvo JP; von Kobbe C
Mech Ageing Dev; 2007; 128(7-8):423-36. PubMed ID: 17624410
[TBL] [Abstract][Full Text] [Related]
28. Diverse dealings of the Werner helicase/nuclease.
Cheng WH; Bohr VA
Sci Aging Knowledge Environ; 2003 Aug; 2003(31):PE22. PubMed ID: 12904570
[TBL] [Abstract][Full Text] [Related]
29. TRF2 recruits the Werner syndrome (WRN) exonuclease for processing of telomeric DNA.
Machwe A; Xiao L; Orren DK
Oncogene; 2004 Jan; 23(1):149-56. PubMed ID: 14712220
[TBL] [Abstract][Full Text] [Related]
30. Failure to complement abnormal phenotypes of simian virus 40-transformed Werner syndrome cells by introduction of a normal human chromosome 8.
Kodama S; Kashino G; Suzuki K; Takatsuji T; Okumura Y; Oshimura M; Watanabe M; Barrett JC
Cancer Res; 1998 Nov; 58(22):5188-95. PubMed ID: 9823331
[TBL] [Abstract][Full Text] [Related]
31. Telomere dysfunction as a cause of genomic instability in Werner syndrome.
Crabbe L; Jauch A; Naeger CM; Holtgreve-Grez H; Karlseder J
Proc Natl Acad Sci U S A; 2007 Feb; 104(7):2205-10. PubMed ID: 17284601
[TBL] [Abstract][Full Text] [Related]
32. Bloom's syndrome: Why not premature aging?: A comparison of the BLM and WRN helicases.
de Renty C; Ellis NA
Ageing Res Rev; 2017 Jan; 33():36-51. PubMed ID: 27238185
[TBL] [Abstract][Full Text] [Related]
33. The Werner syndrome helicase/exonuclease (WRN) disrupts and degrades D-loops in vitro.
Orren DK; Theodore S; Machwe A
Biochemistry; 2002 Nov; 41(46):13483-8. PubMed ID: 12427008
[TBL] [Abstract][Full Text] [Related]
34. Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer.
Agrelo R; Cheng WH; Setien F; Ropero S; Espada J; Fraga MF; Herranz M; Paz MF; Sanchez-Cespedes M; Artiga MJ; Guerrero D; Castells A; von Kobbe C; Bohr VA; Esteller M
Proc Natl Acad Sci U S A; 2006 Jun; 103(23):8822-7. PubMed ID: 16723399
[TBL] [Abstract][Full Text] [Related]
35. Werner syndrome protein: biochemical properties and functional interactions.
Bohr VA; Cooper M; Orren D; Machwe A; Piotrowski J; Sommers J; Karmakar P; Brosh R
Exp Gerontol; 2000 Sep; 35(6-7):695-702. PubMed ID: 11053659
[TBL] [Abstract][Full Text] [Related]
36. Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.
von Kobbe C; Harrigan JA; Schreiber V; Stiegler P; Piotrowski J; Dawut L; Bohr VA
Nucleic Acids Res; 2004; 32(13):4003-14. PubMed ID: 15292449
[TBL] [Abstract][Full Text] [Related]
37. Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA.
Shen JC; Loeb LA
Nucleic Acids Res; 2000 Sep; 28(17):3260-8. PubMed ID: 10954593
[TBL] [Abstract][Full Text] [Related]
38. Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome.
Hui CW; St-Pierre MK; Detuncq J; Aumailley L; Dubois MJ; Couture V; Skuk D; Marette A; Tremblay JP; Lebel M; Tremblay MÈ
Brain Behav Immun; 2018 Oct; 73():450-469. PubMed ID: 29908963
[TBL] [Abstract][Full Text] [Related]
39. Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.
Crabbe L; Verdun RE; Haggblom CI; Karlseder J
Science; 2004 Dec; 306(5703):1951-3. PubMed ID: 15591207
[TBL] [Abstract][Full Text] [Related]
40. Werner interacting protein 1 promotes binding of Werner protein to template-primer DNA.
Kanamori M; Seki M; Yoshimura A; Tsurimoto T; Tada S; Enomoto T
Biol Pharm Bull; 2011; 34(8):1314-8. PubMed ID: 21804224
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]