BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 31082191)

  • 1. Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms.
    Ketkar A; Maddukuri L; Penthala NR; Reed MR; Zafar MK; Crooks PA; Eoff RL
    ACS Chem Biol; 2019 Jun; 14(6):1337-1351. PubMed ID: 31082191
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Small-Molecule Inhibitor of Human DNA Polymerase η Potentiates the Effects of Cisplatin in Tumor Cells.
    Zafar MK; Maddukuri L; Ketkar A; Penthala NR; Reed MR; Eddy S; Crooks PA; Eoff RL
    Biochemistry; 2018 Feb; 57(7):1262-1273. PubMed ID: 29345908
    [TBL] [Abstract][Full Text] [Related]  

  • 3. N-Aroyl indole thiobarbituric acids as inhibitors of DNA repair and replication stress response polymerases.
    Coggins GE; Maddukuri L; Penthala NR; Hartman JH; Eddy S; Ketkar A; Crooks PA; Eoff RL
    ACS Chem Biol; 2013 Aug; 8(8):1722-9. PubMed ID: 23679919
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human Translesion Polymerase κ Exhibits Enhanced Activity and Reduced Fidelity Two Nucleotides from G-Quadruplex DNA.
    Eddy S; Tillman M; Maddukuri L; Ketkar A; Zafar MK; Eoff RL
    Biochemistry; 2016 Sep; 55(37):5218-29. PubMed ID: 27525498
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human DNA polymerase η has reverse transcriptase activity in cellular environments.
    Su Y; Ghodke PP; Egli M; Li L; Wang Y; Guengerich FP
    J Biol Chem; 2019 Apr; 294(15):6073-6081. PubMed ID: 30842261
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Translesion synthesis of 6-nitrochrysene-derived 2'-deoxyadenosine adduct in human cells.
    Powell BV; Bacurio JHT; Basu AK
    DNA Repair (Amst); 2020 Nov; 95():102935. PubMed ID: 32721818
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Site-Specific Incorporation of
    Pande P; Rebello KR; Chatterjee A; Naldiga S; Basu AK
    Chem Res Toxicol; 2020 Jul; 33(7):1997-2005. PubMed ID: 32551527
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein.
    Tissier A; Kannouche P; Reck MP; Lehmann AR; Fuchs RP; Cordonnier A
    DNA Repair (Amst); 2004 Nov; 3(11):1503-14. PubMed ID: 15380106
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells.
    Bostian AC; Maddukuri L; Reed MR; Savenka T; Hartman JH; Davis L; Pouncey DL; Miller GP; Eoff RL
    Chem Res Toxicol; 2016 Jan; 29(1):101-8. PubMed ID: 26651356
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence for the kinetic partitioning of polymerase activity on G-quadruplex DNA.
    Eddy S; Maddukuri L; Ketkar A; Zafar MK; Henninger EE; Pursell ZF; Eoff RL
    Biochemistry; 2015 May; 54(20):3218-30. PubMed ID: 25903680
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural and functional elucidation of the mechanism promoting error-prone synthesis by human DNA polymerase kappa opposite the 7,8-dihydro-8-oxo-2'-deoxyguanosine adduct.
    Irimia A; Eoff RL; Guengerich FP; Egli M
    J Biol Chem; 2009 Aug; 284(33):22467-22480. PubMed ID: 19542228
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Error-prone replication of a 5-formylcytosine-mediated DNA-peptide cross-link in human cells.
    Naldiga S; Ji S; Thomforde J; Nicolae CM; Lee M; Zhang Z; Moldovan GL; Tretyakova NY; Basu AK
    J Biol Chem; 2019 Jul; 294(27):10619-10627. PubMed ID: 31138652
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide.
    Latancia MT; Moreno NC; Leandro GS; Ribeiro VC; de Souza I; Vieira WKM; Bastos AU; Hoch NC; Rocha CRR; Menck CFM
    Mutat Res Genet Toxicol Environ Mutagen; 2022 Jun; 878():503498. PubMed ID: 35649682
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity.
    Ketkar A; Zafar MK; Maddukuri L; Yamanaka K; Banerjee S; Egli M; Choi JY; Lloyd RS; Eoff RL
    Chem Res Toxicol; 2013 Feb; 26(2):221-32. PubMed ID: 23305233
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Filling gaps in translesion DNA synthesis in human cells.
    Quinet A; Lerner LK; Martins DJ; Menck CFM
    Mutat Res Genet Toxicol Environ Mutagen; 2018 Dec; 836(Pt B):127-142. PubMed ID: 30442338
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ.
    Yamanaka K; Dorjsuren D; Eoff RL; Egli M; Maloney DJ; Jadhav A; Simeonov A; Lloyd RS
    PLoS One; 2012; 7(10):e45032. PubMed ID: 23056190
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Minor Groove 3-Deaza-Adenosine Analogues: Synthesis and Bypass in Translesion DNA Synthesis.
    Malvezzi S; Angelov T; Sturla SJ
    Chemistry; 2017 Jan; 23(5):1101-1109. PubMed ID: 27862447
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutagenic Bypass of an Oxidized Abasic Lesion-Induced DNA Interstrand Cross-Link Analogue by Human Translesion Synthesis DNA Polymerases.
    Xu W; Ouellette A; Ghosh S; O'Neill TC; Greenberg MM; Zhao L
    Biochemistry; 2015 Dec; 54(50):7409-22. PubMed ID: 26626537
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human DNA polymerase η accommodates RNA for strand extension.
    Su Y; Egli M; Guengerich FP
    J Biol Chem; 2017 Nov; 292(44):18044-18051. PubMed ID: 28972162
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Homology modeling of four Y-family, lesion-bypass DNA polymerases: the case that E. coli Pol IV and human Pol kappa are orthologs, and E. coli Pol V and human Pol eta are orthologs.
    Lee CH; Chandani S; Loechler EL
    J Mol Graph Model; 2006 Sep; 25(1):87-102. PubMed ID: 16386932
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.