BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

426 related articles for article (PubMed ID: 31085352)

  • 1. New explanation for autosomal dominant high bone mass: Mutation of low-density lipoprotein receptor-related protein 6.
    Whyte MP; McAlister WH; Zhang F; Bijanki VN; Nenninger A; Gottesman GS; Lin EL; Huskey M; Duan S; Dahir K; Mumm S
    Bone; 2019 Oct; 127():228-243. PubMed ID: 31085352
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High bone mass from mutation of low-density lipoprotein receptor-related protein 6 (LRP6).
    Brance ML; Brun LR; Cóccaro NM; Aravena A; Duan S; Mumm S; Whyte MP
    Bone; 2020 Dec; 141():115550. PubMed ID: 32730923
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LRP6 High Bone Mass Characterized in Two Generations Harboring a Unique Mutation of Low-Density Lipoprotein Receptor-Related Protein 6.
    Whyte MP; Mumm S; Baker JC; Zhang F; Sedighi H; Duan S; Cundy T
    JBMR Plus; 2023 Apr; 7(4):e10717. PubMed ID: 37065631
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Levels of serotonin, sclerostin, bone turnover markers as well as bone density and microarchitecture in patients with high-bone-mass phenotype due to a mutation in Lrp5.
    Frost M; Andersen T; Gossiel F; Hansen S; Bollerslev J; van Hul W; Eastell R; Kassem M; Brixen K
    J Bone Miner Res; 2011 Aug; 26(8):1721-8. PubMed ID: 21351148
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Clinical Phenotype and Relevance of LRP5 and LRP6 Variants in Patients With Early-Onset Osteoporosis (EOOP).
    Stürznickel J; Rolvien T; Delsmann A; Butscheidt S; Barvencik F; Mundlos S; Schinke T; Kornak U; Amling M; Oheim R
    J Bone Miner Res; 2021 Feb; 36(2):271-282. PubMed ID: 33118644
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oropharyngeal skeletal disease accompanying high bone mass and novel LRP5 mutation.
    Rickels MR; Zhang X; Mumm S; Whyte MP
    J Bone Miner Res; 2005 May; 20(5):878-85. PubMed ID: 15824861
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutations in Known Monogenic High Bone Mass Loci Only Explain a Small Proportion of High Bone Mass Cases.
    Gregson CL; Wheeler L; Hardcastle SA; Appleton LH; Addison KA; Brugmans M; Clark GR; Ward KA; Paggiosi M; Stone M; Thomas J; Agarwal R; Poole KE; McCloskey E; Fraser WD; Williams E; Bullock AN; Davey Smith G; Brown MA; Tobias JH; Duncan EL
    J Bone Miner Res; 2016 Mar; 31(3):640-9. PubMed ID: 26348019
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel mutation in LRP5 gene cause rare osteosclerosis: cases studies and literature review.
    Zhao D; Sun L; Zheng W; Hu J; Zhou B; Wang O; Jiang Y; Xia W; Xing X; Li M
    Mol Genet Genomics; 2023 May; 298(3):683-692. PubMed ID: 36971833
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of Lrp5 HBM-causing mutations in Cathepsin-K expressing cells alters bone metabolism.
    Kang KS; Hong JM; Horan DJ; Lim KE; Bullock WA; Bruzzaniti A; Hann S; Warman ML; Robling AG
    Bone; 2019 Mar; 120():166-175. PubMed ID: 30409757
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel LRP5 missense mutation in a patient with a high bone mass phenotype results in decreased DKK1-mediated inhibition of Wnt signaling.
    Balemans W; Devogelaer JP; Cleiren E; Piters E; Caussin E; Van Hul W
    J Bone Miner Res; 2007 May; 22(5):708-16. PubMed ID: 17295608
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-based mutation analysis shows the importance of LRP5 beta-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling.
    Bhat BM; Allen KM; Liu W; Graham J; Morales A; Anisowicz A; Lam HS; McCauley C; Coleburn V; Cain M; Fortier E; Bhat RA; Bex FJ; Yaworsky PJ
    Gene; 2007 Apr; 391(1-2):103-12. PubMed ID: 17276019
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Elevated circulating Sclerostin concentrations in individuals with high bone mass, with and without LRP5 mutations.
    Gregson CL; Poole KE; McCloskey EV; Duncan EL; Rittweger J; Fraser WD; Smith GD; Tobias JH
    J Clin Endocrinol Metab; 2014 Aug; 99(8):2897-907. PubMed ID: 24606091
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition.
    Riddle RC; Diegel CR; Leslie JM; Van Koevering KK; Faugere MC; Clemens TL; Williams BO
    PLoS One; 2013; 8(5):e63323. PubMed ID: 23675479
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Co-deletion of Lrp5 and Lrp6 in the skeleton severely diminishes bone gain from sclerostin antibody administration.
    Lim KE; Bullock WA; Horan DJ; Williams BO; Warman ML; Robling AG
    Bone; 2021 Feb; 143():115708. PubMed ID: 33164872
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity.
    Ellies DL; Viviano B; McCarthy J; Rey JP; Itasaki N; Saunders S; Krumlauf R
    J Bone Miner Res; 2006 Nov; 21(11):1738-49. PubMed ID: 17002572
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reversing LRP5-dependent osteoporosis and SOST deficiency-induced sclerosing bone disorders by altering WNT signaling activity.
    Chang MK; Kramer I; Keller H; Gooi JH; Collett C; Jenkins D; Ettenberg SA; Cong F; Halleux C; Kneissel M
    J Bone Miner Res; 2014 Jan; 29(1):29-42. PubMed ID: 23901037
    [TBL] [Abstract][Full Text] [Related]  

  • 17. LRP5 high bone mass (Worth-type autosomal dominant endosteal hyperostosis): case report and historical review of the literature.
    De Mattia G; Maffi M; Mosca M; Mazzantini M
    Arch Osteoporos; 2023 Sep; 18(1):112. PubMed ID: 37659026
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel familial mutation of LRP5 causing high bone mass: Genetic analysis, clinical presentation, and characterization of bone matrix mineralization.
    Roetzer KM; Uyanik G; Brehm A; Zwerina J; Zandieh S; Czech T; Roschger P; Misof BM; Klaushofer K
    Bone; 2018 Feb; 107():154-160. PubMed ID: 29208525
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High Bone Mass-Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo.
    Niziolek PJ; MacDonald BT; Kedlaya R; Zhang M; Bellido T; He X; Warman ML; Robling AG
    J Bone Miner Res; 2015 Oct; 30(10):1822-30. PubMed ID: 25808845
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Clinical features, treatment, and follow-up of OPPG and high-bone-mass disorders: LRP5 is a key regulator of bone mass.
    Ren N; Lv S; Li X; Shao C; Wang Z; Mei Y; Yang W; Fu W; Hu Y; Sha L; Hu W; Zhang Z; Wang C
    Osteoporos Int; 2024 Apr; ():. PubMed ID: 38625381
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.