BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

454 related articles for article (PubMed ID: 31088931)

  • 21. Induction of p53-mediated transcription and apoptosis by exportin-1 (XPO1) inhibition in mantle cell lymphoma.
    Yoshimura M; Ishizawa J; Ruvolo V; Dilip A; Quintás-Cardama A; McDonnell TJ; Neelapu SS; Kwak LW; Shacham S; Kauffman M; Tabe Y; Yokoo M; Kimura S; Andreeff M; Kojima K
    Cancer Sci; 2014 Jul; 105(7):795-801. PubMed ID: 24766216
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Ribosomal Biogenesis and Translational Flux Inhibition by the Selective Inhibitor of Nuclear Export (SINE) XPO1 Antagonist KPT-185.
    Tabe Y; Kojima K; Yamamoto S; Sekihara K; Matsushita H; Davis RE; Wang Z; Ma W; Ishizawa J; Kazuno S; Kauffman M; Shacham S; Fujimura T; Ueno T; Miida T; Andreeff M
    PLoS One; 2015; 10(9):e0137210. PubMed ID: 26340096
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Exportin-1 is critical for cell proliferation and survival in adult T cell leukemia.
    Ishikawa C; Mori N
    Invest New Drugs; 2022 Aug; 40(4):718-727. PubMed ID: 35477814
    [TBL] [Abstract][Full Text] [Related]  

  • 24. KSHV hijacks FoxO1 to promote cell proliferation and cellular transformation by antagonizing oxidative stress.
    Li T; Gao SJ
    J Med Virol; 2023 Mar; 95(3):e28676. PubMed ID: 36929740
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Cellular and viral oncogenes: the key to unlocking unknowns of Kaposi's sarcoma-associated herpesvirus pathogenesis.
    Hussein HAM; Okafor IB; Walker LR; Abdel-Raouf UM; Akula SM
    Arch Virol; 2018 Oct; 163(10):2633-2643. PubMed ID: 29936609
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A CRISPR-Cas9 screen identifies mitochondrial translation as an essential process in latent KSHV infection of human endothelial cells.
    Holmes DL; Vogt DT; Lagunoff M
    Proc Natl Acad Sci U S A; 2020 Nov; 117(45):28384-28392. PubMed ID: 33122441
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Specific inhibition of the nuclear exporter exportin-1 attenuates kidney cancer growth.
    Wettersten HI; Landesman Y; Friedlander S; Shacham S; Kauffman M; Weiss RH
    PLoS One; 2014; 9(12):e113867. PubMed ID: 25461627
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus.
    Flore O; Rafii S; Ely S; O'Leary JJ; Hyjek EM; Cesarman E
    Nature; 1998 Aug; 394(6693):588-92. PubMed ID: 9707121
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus.
    Zhu Y; Li T; Ramos da Silva S; Lee JJ; Lu C; Eoh H; Jung JU; Gao SJ
    mBio; 2017 Aug; 8(4):. PubMed ID: 28811348
    [TBL] [Abstract][Full Text] [Related]  

  • 30. XPO1 inhibition synergizes with PARP1 inhibition in small cell lung cancer by targeting nuclear transport of FOXO3a.
    Wang J; Sun T; Meng Z; Wang L; Li M; Chen J; Qin T; Yu J; Zhang M; Bie Z; Dong Z; Jiang X; Lin L; Zhang C; Liu Z; Jiang R; Yang G; Li L; Zhang Y; Huang D
    Cancer Lett; 2021 Apr; 503():197-212. PubMed ID: 33493586
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276.
    Schmidt J; Braggio E; Kortuem KM; Egan JB; Zhu YX; Xin CS; Tiedemann RE; Palmer SE; Garbitt VM; McCauley D; Kauffman M; Shacham S; Chesi M; Bergsagel PL; Stewart AK
    Leukemia; 2013 Dec; 27(12):2357-65. PubMed ID: 23752175
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Anti-tumor efficacy of Selinexor (KPT-330) in gastric cancer is dependent on nuclear accumulation of p53 tumor suppressor.
    Subhash VV; Yeo MS; Wang L; Tan SH; Wong FY; Thuya WL; Tan WL; Peethala PC; Soe MY; Tan DSP; Padmanabhan N; Baloglu E; Shacham S; Tan P; Koeffler HP; Yong WP
    Sci Rep; 2018 Aug; 8(1):12248. PubMed ID: 30115935
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Genome-Wide Identification of Direct RTA Targets Reveals Key Host Factors for Kaposi's Sarcoma-Associated Herpesvirus Lytic Reactivation.
    Papp B; Motlagh N; Smindak RJ; Jin Jang S; Sharma A; Alonso JD; Toth Z
    J Virol; 2019 Mar; 93(5):. PubMed ID: 30541837
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Novel cellular genes essential for transformation of endothelial cells by Kaposi's sarcoma-associated herpesvirus.
    Raggo C; Ruhl R; McAllister S; Koon H; Dezube BJ; Früh K; Moses AV
    Cancer Res; 2005 Jun; 65(12):5084-95. PubMed ID: 15958552
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Upregulation of MicroRNA 711 Mediates HIV-1 Vpr Promotion of Kaposi's Sarcoma-Associated Herpesvirus Latency and Induction of Pro-proliferation and Pro-survival Cytokines by Targeting the Notch/NF-κB-Signaling Axis.
    Yan Q; Zhao R; Shen C; Wang F; Li W; Gao SJ; Lu C
    J Virol; 2018 Sep; 92(18):. PubMed ID: 29976660
    [TBL] [Abstract][Full Text] [Related]  

  • 36. XPO1 (CRM1) inhibition represses STAT3 activation to drive a survivin-dependent oncogenic switch in triple-negative breast cancer.
    Cheng Y; Holloway MP; Nguyen K; McCauley D; Landesman Y; Kauffman MG; Shacham S; Altura RA
    Mol Cancer Ther; 2014 Mar; 13(3):675-86. PubMed ID: 24431073
    [TBL] [Abstract][Full Text] [Related]  

  • 37. G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator.
    Bais C; Santomasso B; Coso O; Arvanitakis L; Raaka EG; Gutkind JS; Asch AS; Cesarman E; Gershengorn MC; Mesri EA
    Nature; 1998 Jan; 391(6662):86-9. PubMed ID: 9422510
    [TBL] [Abstract][Full Text] [Related]  

  • 38. K1 and K15 of Kaposi's Sarcoma-Associated Herpesvirus Are Partial Functional Homologues of Latent Membrane Protein 2A of Epstein-Barr Virus.
    Steinbrück L; Gustems M; Medele S; Schulz TF; Lutter D; Hammerschmidt W
    J Virol; 2015 Jul; 89(14):7248-61. PubMed ID: 25948739
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cytotoxic Drugs Activate KSHV Lytic Cycle in Latently Infected PEL Cells by Inducing a Moderate ROS Increase Controlled by HSF1, NRF2 and p62/SQSTM1.
    Granato M; Gilardini Montani MS; Angiolillo C; D'Orazi G; Faggioni A; Cirone M
    Viruses; 2018 Dec; 11(1):. PubMed ID: 30586869
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Inhibition of XPO1 impairs cholangiocarcinoma cell proliferation by triggering p53 intranuclear accumulation.
    Zhao C; Ma B; Yang ZY; Li O; Liu SL; Pan LJ; Gong W; Dong P; Shu YJ
    Cancer Med; 2023 Mar; 12(5):5751-5763. PubMed ID: 36200270
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 23.