329 related articles for article (PubMed ID: 31092272)
1. Mitochondrially targeted p53 or DBD subdomain is superior to wild type p53 in ovarian cancer cells even with strong dominant negative mutant p53.
Lu P; Vander Mause ER; Redd Bowman KE; Brown SM; Ahne L; Lim CS
J Ovarian Res; 2019 May; 12(1):45. PubMed ID: 31092272
[TBL] [Abstract][Full Text] [Related]
2. Delivery of a monomeric p53 subdomain with mitochondrial targeting signals from pro-apoptotic Bak or Bax.
Matissek KJ; Okal A; Mossalam M; Lim CS
Pharm Res; 2014 Sep; 31(9):2503-15. PubMed ID: 24633417
[TBL] [Abstract][Full Text] [Related]
3. The DNA binding domain of p53 is sufficient to trigger a potent apoptotic response at the mitochondria.
Matissek KJ; Mossalam M; Okal A; Lim CS
Mol Pharm; 2013 Oct; 10(10):3592-602. PubMed ID: 23968395
[TBL] [Abstract][Full Text] [Related]
4. Direct induction of apoptosis using an optimal mitochondrially targeted p53.
Mossalam M; Matissek KJ; Okal A; Constance JE; Lim CS
Mol Pharm; 2012 May; 9(5):1449-58. PubMed ID: 22380534
[TBL] [Abstract][Full Text] [Related]
5. p53-Bad: A Novel Tumor Suppressor/Proapoptotic Factor Hybrid Directed to the Mitochondria for Ovarian Cancer Gene Therapy.
Lu P; Redd Bowman KE; Brown SM; Joklik-Mcleod M; Vander Mause ER; Nguyen HTN; Lim CS
Mol Pharm; 2019 Aug; 16(8):3386-3398. PubMed ID: 31241338
[TBL] [Abstract][Full Text] [Related]
6. Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53.
Jones NA; Turner J; McIlwrath AJ; Brown R; Dive C
Mol Pharmacol; 1998 May; 53(5):819-26. PubMed ID: 9584207
[TBL] [Abstract][Full Text] [Related]
7. Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK.
Ling YH; Lin R; Perez-Soler R
Mol Pharmacol; 2008 Sep; 74(3):793-806. PubMed ID: 18524889
[TBL] [Abstract][Full Text] [Related]
8. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
Zhang J; Huang K; O'Neill KL; Pang X; Luo X
Cell Death Dis; 2016 Jun; 7(6):e2266. PubMed ID: 27310874
[TBL] [Abstract][Full Text] [Related]
9. Bak compensated for Bax in p53-null cells to release cytochrome c for the initiation of mitochondrial signaling during Withanolide D-induced apoptosis.
Mondal S; Bhattacharya K; Mallick A; Sangwan R; Mandal C
PLoS One; 2012; 7(3):e34277. PubMed ID: 22479585
[TBL] [Abstract][Full Text] [Related]
10. Mitochondrial p53 phosphorylation induces Bak-mediated and caspase-independent cell death.
Wang J; Guo W; Zhou H; Luo N; Nie C; Zhao X; Yuan Z; Liu X; Wei Y
Oncotarget; 2015 Jul; 6(19):17192-205. PubMed ID: 25980443
[TBL] [Abstract][Full Text] [Related]
11. Tumor suppressor protein p53 promotes 2-methoxyestradiol-induced activation of Bak and Bax, leading to mitochondria-dependent apoptosis in human colon cancer HCT116 cells.
Lee JY; Jee SB; Park WY; Choi YJ; Kim B; Kim YH; Jun do Y; Kim YH
J Microbiol Biotechnol; 2014 Dec; 24(12):1654-63. PubMed ID: 25179905
[TBL] [Abstract][Full Text] [Related]
12. Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.
Leu JI; Dumont P; Hafey M; Murphy ME; George DL
Nat Cell Biol; 2004 May; 6(5):443-50. PubMed ID: 15077116
[TBL] [Abstract][Full Text] [Related]
13. The tetramerization domain of p53 is required for efficient BAK oligomerization.
Pietsch EC; Leu JI; Frank A; Dumont P; George DL; Murphy ME
Cancer Biol Ther; 2007 Oct; 6(10):1576-83. PubMed ID: 17895645
[TBL] [Abstract][Full Text] [Related]
14. Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells.
Matsumoto M; Nakajima W; Seike M; Gemma A; Tanaka N
Biochem Biophys Res Commun; 2016 Apr; 473(2):490-6. PubMed ID: 26996126
[TBL] [Abstract][Full Text] [Related]
15. Mitochondrially targeted Bcl-2 and Bcl-X(L) chimeras elicit different apoptotic responses.
Liu S; Pereira NA; Teo JJ; Miller P; Shah P; Song Z
Mol Cells; 2007 Dec; 24(3):378-87. PubMed ID: 18182854
[TBL] [Abstract][Full Text] [Related]
16. Novel pyrrolopyrimidine derivatives induce p53-independent apoptosis via the mitochondrial pathway in colon cancer cells.
Kilic-Kurt Z; Aka Y; Kutuk O
Chem Biol Interact; 2020 Oct; 330():109236. PubMed ID: 32866467
[TBL] [Abstract][Full Text] [Related]
17. Benzo(a)pyrene-7,8-diol-9,10-epoxide induced p53-independent necrosis via the mitochondria-associated pathway involving Bax and Bak activation.
Zhang W; Liu N; Wang X; Jin X; Du H; Peng G; Xue J
Hum Exp Toxicol; 2015 Feb; 34(2):179-90. PubMed ID: 24837741
[TBL] [Abstract][Full Text] [Related]
18. Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells.
Hemmati PG; Güner D; Gillissen B; Wendt J; von Haefen C; Chinnadurai G; Dörken B; Daniel PT
Oncogene; 2006 Oct; 25(50):6582-94. PubMed ID: 16847458
[TBL] [Abstract][Full Text] [Related]
19. A three-helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax.
George NM; Evans JJ; Luo X
Genes Dev; 2007 Aug; 21(15):1937-48. PubMed ID: 17671092
[TBL] [Abstract][Full Text] [Related]
20. Synthetic Bichalcone TSWU-BR23 Induces Apoptosis of Human Colon Cancer HT-29 Cells by p53-Mediated Mitochondrial Oligomerization of BAX/BAK and Lipid Raft Localization of CD95/FADD.
Lin ML; Chen SS; Wu TS
Anticancer Res; 2015 Oct; 35(10):5407-16. PubMed ID: 26408703
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
