250 related articles for article (PubMed ID: 31097586)
1. TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy.
McLoughlin MR; Orlicky DJ; Prigge JR; Krishna P; Talago EA; Cavigli IR; Eriksson S; Miller CG; Kundert JA; Sayin VI; Sabol RA; Heinemann J; Brandenberger LO; Iverson SV; Bothner B; Papagiannakopoulos T; Shearn CT; Arnér ESJ; Schmidt EE
Proc Natl Acad Sci U S A; 2019 Jun; 116(23):11408-11417. PubMed ID: 31097586
[TBL] [Abstract][Full Text] [Related]
2. Supplemental Ascorbate Diminishes DNA Damage Yet Depletes Glutathione and Increases Acute Liver Failure in a Mouse Model of Hepatic Antioxidant System Disruption.
Miller CG; Kundert JA; Prigge JR; Amato JA; Perez AE; Coppo L; Rizzo GN; Kavanaugh MP; Orlicky DJ; Shearn CT; Schmidt EE
Antioxidants (Basel); 2021 Feb; 10(3):. PubMed ID: 33673577
[TBL] [Abstract][Full Text] [Related]
3. Hepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase.
Prigge JR; Coppo L; Martin SS; Ogata F; Miller CG; Bruschwein MD; Orlicky DJ; Shearn CT; Kundert JA; Lytchier J; Herr AE; Mattsson Å; Taylor MP; Gustafsson TN; Arnér ESJ; Holmgren A; Schmidt EE
Cell Rep; 2017 Jun; 19(13):2771-2781. PubMed ID: 28658624
[TBL] [Abstract][Full Text] [Related]
4. Interplay between cytosolic disulfide reductase systems and the Nrf2/Keap1 pathway.
Schmidt EE
Biochem Soc Trans; 2015 Aug; 43(4):632-8. PubMed ID: 26551704
[TBL] [Abstract][Full Text] [Related]
5. Nelumbo nucifera leaf extract treatment attenuated preneoplastic lesions and oxidative stress in the livers of diethylnitrosamine-treated rats.
Horng CT; Huang CW; Yang MY; Chen TH; Chang YC; Wang CJ
Environ Toxicol; 2017 Nov; 32(11):2327-2340. PubMed ID: 28804948
[TBL] [Abstract][Full Text] [Related]
6. A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification.
Iverson SV; Eriksson S; Xu J; Prigge JR; Talago EA; Meade TA; Meade ES; Capecchi MR; Arnér ES; Schmidt EE
Free Radic Biol Med; 2013 Oct; 63():369-80. PubMed ID: 23743293
[TBL] [Abstract][Full Text] [Related]
7. Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress.
Harvey CJ; Thimmulappa RK; Singh A; Blake DJ; Ling G; Wakabayashi N; Fujii J; Myers A; Biswal S
Free Radic Biol Med; 2009 Feb; 46(4):443-53. PubMed ID: 19028565
[TBL] [Abstract][Full Text] [Related]
8. Does hepatic oxidative stress enhance activation of nuclear factor-E2-related factor in patients with nonalcoholic steatohepatitis?
Takahashi Y; Kobayashi Y; Kawata K; Kawamura K; Sumiyoshi S; Noritake H; Watanabe S; Chida T; Souda K; Sakaguchi T; Nakamura H; Suda T
Antioxid Redox Signal; 2014 Jan; 20(3):538-43. PubMed ID: 23822105
[TBL] [Abstract][Full Text] [Related]
9. Nrf2 protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced oxidative injury and steatohepatitis.
Lu H; Cui W; Klaassen CD
Toxicol Appl Pharmacol; 2011 Oct; 256(2):122-35. PubMed ID: 21846477
[TBL] [Abstract][Full Text] [Related]
10. Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1.
Prigge JR; Eriksson S; Iverson SV; Meade TA; Capecchi MR; Arnér ES; Schmidt EE
Free Radic Biol Med; 2012 Feb; 52(4):803-10. PubMed ID: 22198266
[TBL] [Abstract][Full Text] [Related]
11. A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems.
Dóka É; Pader I; Bíró A; Johansson K; Cheng Q; Ballagó K; Prigge JR; Pastor-Flores D; Dick TP; Schmidt EE; Arnér ES; Nagy P
Sci Adv; 2016 Jan; 2(1):e1500968. PubMed ID: 26844296
[TBL] [Abstract][Full Text] [Related]
12. Enhanced hepatic Nrf2 activation after ursodeoxycholic acid treatment in patients with primary biliary cirrhosis.
Kawata K; Kobayashi Y; Souda K; Kawamura K; Sumiyoshi S; Takahashi Y; Noritake H; Watanabe S; Suehiro T; Nakamura H
Antioxid Redox Signal; 2010 Aug; 13(3):259-68. PubMed ID: 20055754
[TBL] [Abstract][Full Text] [Related]
13. Antioxidative effects of diallyl trisulfide on hydrogen peroxide-induced cytotoxicity through regulation of nuclear factor-E2-related factor-mediated thioredoxin reductase 1 expression in C2C12 skeletal muscle myoblast cells.
Kang JS; Kim GY; Kim BW; Choi YH
Gen Physiol Biophys; 2017 Apr; 36(2):129-139. PubMed ID: 28218609
[TBL] [Abstract][Full Text] [Related]
14. GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway.
Li J; Wang Q; Yang Y; Lei C; Yang F; Liang L; Chen C; Xia J; Wang K; Tang N
J Exp Clin Cancer Res; 2019 Oct; 38(1):438. PubMed ID: 31666108
[TBL] [Abstract][Full Text] [Related]
15. CDCA2 protects against oxidative stress by promoting BRCA1-NRF2 signaling in hepatocellular carcinoma.
Wang S; Cao K; Liao Y; Zhang W; Zheng J; Li X; Huang M; Zhong Y; Hu X; Chen D; Wang Y
Oncogene; 2021 Jun; 40(25):4368-4383. PubMed ID: 34103686
[TBL] [Abstract][Full Text] [Related]
16. GSR is not essential for the maintenance of antioxidant defenses in mouse cochlea: Possible role of the thioredoxin system as a functional backup for GSR.
Han C; Kim MJ; Ding D; Park HJ; White K; Walker L; Gu T; Tanokura M; Yamasoba T; Linser P; Salvi R; Someya S
PLoS One; 2017; 12(7):e0180817. PubMed ID: 28686716
[TBL] [Abstract][Full Text] [Related]
17. TrxR1 as a potent regulator of the Nrf2-Keap1 response system.
Cebula M; Schmidt EE; Arnér ES
Antioxid Redox Signal; 2015 Oct; 23(10):823-53. PubMed ID: 26058897
[TBL] [Abstract][Full Text] [Related]
18. Activation of the Nrf2-regulated antioxidant cell response inhibits HEMA-induced oxidative stress and supports cell viability.
Gallorini M; Petzel C; Bolay C; Hiller KA; Cataldi A; Buchalla W; Krifka S; Schweikl H
Biomaterials; 2015 Jul; 56():114-28. PubMed ID: 25934285
[TBL] [Abstract][Full Text] [Related]
19. Oxidative stress indicated by elevated expression of Nrf2 and 8-OHdG promotes hepatocellular carcinoma progression.
Ma-On C; Sanpavat A; Whongsiri P; Suwannasin S; Hirankarn N; Tangkijvanich P; Boonla C
Med Oncol; 2017 Apr; 34(4):57. PubMed ID: 28281193
[TBL] [Abstract][Full Text] [Related]
20. Genetic activation of Nrf2 protects against fasting-induced oxidative stress in livers of mice.
Zhang YK; Wu KC; Klaassen CD
PLoS One; 2013; 8(3):e59122. PubMed ID: 23527105
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]