753 related articles for article (PubMed ID: 31097622)
1. Increased Lysosomal Exocytosis Induced by Lysosomal Ca
Tsunemi T; Perez-Rosello T; Ishiguro Y; Yoroisaka A; Jeon S; Hamada K; Rammonhan M; Wong YC; Xie Z; Akamatsu W; Mazzulli JR; Surmeier DJ; Hattori N; Krainc D
J Neurosci; 2019 Jul; 39(29):5760-5772. PubMed ID: 31097622
[TBL] [Abstract][Full Text] [Related]
2. Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.
Mazzulli JR; Zunke F; Tsunemi T; Toker NJ; Jeon S; Burbulla LF; Patnaik S; Sidransky E; Marugan JJ; Sue CM; Krainc D
J Neurosci; 2016 Jul; 36(29):7693-706. PubMed ID: 27445146
[TBL] [Abstract][Full Text] [Related]
3. Astrocytes Protect Human Dopaminergic Neurons from α-Synuclein Accumulation and Propagation.
Tsunemi T; Ishiguro Y; Yoroisaka A; Valdez C; Miyamoto K; Ishikawa K; Saiki S; Akamatsu W; Hattori N; Krainc D
J Neurosci; 2020 Nov; 40(45):8618-8628. PubMed ID: 33046546
[TBL] [Abstract][Full Text] [Related]
4. Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity.
Usenovic M; Knight AL; Ray A; Wong V; Brown KR; Caldwell GA; Caldwell KA; Stagljar I; Krainc D
Hum Mol Genet; 2012 Sep; 21(17):3785-94. PubMed ID: 22645275
[TBL] [Abstract][Full Text] [Related]
5. Deficiency of ATP13A2 leads to lysosomal dysfunction, α-synuclein accumulation, and neurotoxicity.
Usenovic M; Tresse E; Mazzulli JR; Taylor JP; Krainc D
J Neurosci; 2012 Mar; 32(12):4240-6. PubMed ID: 22442086
[TBL] [Abstract][Full Text] [Related]
6. Zn²⁺ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation.
Tsunemi T; Krainc D
Hum Mol Genet; 2014 Jun; 23(11):2791-801. PubMed ID: 24334770
[TBL] [Abstract][Full Text] [Related]
7. α-Synuclein-induced dopaminergic neurodegeneration in a rat model of Parkinson's disease occurs independent of ATP13A2 (PARK9).
Daniel G; Musso A; Tsika E; Fiser A; Glauser L; Pletnikova O; Schneider BL; Moore DJ
Neurobiol Dis; 2015 Jan; 73():229-43. PubMed ID: 25461191
[TBL] [Abstract][Full Text] [Related]
8. ATP13A2/PARK9 regulates secretion of exosomes and α-synuclein.
Tsunemi T; Hamada K; Krainc D
J Neurosci; 2014 Nov; 34(46):15281-7. PubMed ID: 25392495
[TBL] [Abstract][Full Text] [Related]
9. Monoamine Oxidase-B Inhibition Facilitates α-Synuclein Secretion
Nakamura Y; Arawaka S; Sato H; Sasaki A; Shigekiyo T; Takahata K; Tsunekawa H; Kato T
J Neurosci; 2021 Sep; 41(35):7479-7491. PubMed ID: 34290084
[TBL] [Abstract][Full Text] [Related]
10. Lysosomal dysfunction in neurodegeneration: the role of ATP13A2/PARK9.
Usenovic M; Krainc D
Autophagy; 2012 Jun; 8(6):987-8. PubMed ID: 22561922
[TBL] [Abstract][Full Text] [Related]
11. Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity.
Gitler AD; Chesi A; Geddie ML; Strathearn KE; Hamamichi S; Hill KJ; Caldwell KA; Caldwell GA; Cooper AA; Rochet JC; Lindquist S
Nat Genet; 2009 Mar; 41(3):308-15. PubMed ID: 19182805
[TBL] [Abstract][Full Text] [Related]
12. Parkinson's disease-associated ATP13A2/PARK9 functions as a lysosomal H
Fujii T; Nagamori S; Wiriyasermkul P; Zheng S; Yago A; Shimizu T; Tabuchi Y; Okumura T; Fujii T; Takeshima H; Sakai H
Nat Commun; 2023 Apr; 14(1):2174. PubMed ID: 37080960
[TBL] [Abstract][Full Text] [Related]
13. A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy.
Cosden M; Jinn S; Yao L; Gretzula CA; Kandebo M; Toolan D; Hatcher NG; Ma L; Lemaire W; Adam GC; Burlein C; Minnick C; Flick R; Watt ML; Mulhearn J; Fraley M; Drolet RE; Marcus JN; Smith SM
Neurobiol Dis; 2021 Nov; 159():105507. PubMed ID: 34509608
[TBL] [Abstract][Full Text] [Related]
14. ATP13A2 Regulates Cellular α-Synuclein Multimerization, Membrane Association, and Externalization.
Si J; Van den Haute C; Lobbestael E; Martin S; van Veen S; Vangheluwe P; Baekelandt V
Int J Mol Sci; 2021 Mar; 22(5):. PubMed ID: 33799982
[TBL] [Abstract][Full Text] [Related]
15. The Overcrowded Crossroads: Mitochondria, Alpha-Synuclein, and the Endo-Lysosomal System Interaction in Parkinson's Disease.
Lin KJ; Lin KL; Chen SD; Liou CW; Chuang YC; Lin HY; Lin TK
Int J Mol Sci; 2019 Oct; 20(21):. PubMed ID: 31731450
[TBL] [Abstract][Full Text] [Related]
16. Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits.
Schultheis PJ; Fleming SM; Clippinger AK; Lewis J; Tsunemi T; Giasson B; Dickson DW; Mazzulli JR; Bardgett ME; Haik KL; Ekhator O; Chava AK; Howard J; Gannon M; Hoffman E; Chen Y; Prasad V; Linn SC; Tamargo RJ; Westbroek W; Sidransky E; Krainc D; Shull GE
Hum Mol Genet; 2013 May; 22(10):2067-82. PubMed ID: 23393156
[TBL] [Abstract][Full Text] [Related]
17. Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function.
Kim MJ; Jeon S; Burbulla LF; Krainc D
Hum Mol Genet; 2018 Jun; 27(11):1972-1988. PubMed ID: 29579237
[TBL] [Abstract][Full Text] [Related]
18. Hereditary Parkinsonism-Associated Genetic Variations in PARK9 Locus Lead to Functional Impairment of ATPase Type 13A2.
Park JS; Sue CM
Curr Protein Pept Sci; 2017; 18(7):725-732. PubMed ID: 26965689
[TBL] [Abstract][Full Text] [Related]
19. Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.
Prieto Huarcaya S; Drobny A; Marques ARA; Di Spiezio A; Dobert JP; Balta D; Werner C; Rizo T; Gallwitz L; Bub S; Stojkovska I; Belur NR; Fogh J; Mazzulli JR; Xiang W; Fulzele A; Dejung M; Sauer M; Winner B; Rose-John S; Arnold P; Saftig P; Zunke F
Autophagy; 2022 May; 18(5):1127-1151. PubMed ID: 35287553
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration.
Qin H; Buckley JA; Li X; Liu Y; Fox TH; Meares GP; Yu H; Yan Z; Harms AS; Li Y; Standaert DG; Benveniste EN
J Neurosci; 2016 May; 36(18):5144-59. PubMed ID: 27147665
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
