347 related articles for article (PubMed ID: 31097636)
1. Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway.
Lee YR; Chen M; Lee JD; Zhang J; Lin SY; Fu TM; Chen H; Ishikawa T; Chiang SY; Katon J; Zhang Y; Shulga YV; Bester AC; Fung J; Monteleone E; Wan L; Shen C; Hsu CH; Papa A; Clohessy JG; Teruya-Feldstein J; Jain S; Wu H; Matesic L; Chen RH; Wei W; Pandolfi PP
Science; 2019 May; 364(6441):. PubMed ID: 31097636
[TBL] [Abstract][Full Text] [Related]
2. Ubiquitin Ligase Activities of WWP1 Germline Variants K740N and N745S.
Jiang H; Dempsey DR; Cole PA
Biochemistry; 2021 Feb; 60(5):357-364. PubMed ID: 33470109
[TBL] [Abstract][Full Text] [Related]
3. Ubiquitination/de-ubiquitination: A promising therapeutic target for PTEN reactivation in cancer.
Wang K; Liu J; Li YL; Li JP; Zhang R
Biochim Biophys Acta Rev Cancer; 2022 May; 1877(3):188723. PubMed ID: 35314212
[TBL] [Abstract][Full Text] [Related]
4. PIASxα ligase enhances SUMO1 modification of PTEN protein as a SUMO E3 ligase.
Wang W; Chen Y; Wang S; Hu N; Cao Z; Wang W; Tong T; Zhang X
J Biol Chem; 2014 Feb; 289(6):3217-30. PubMed ID: 24344134
[TBL] [Abstract][Full Text] [Related]
5. The HECT family of E3 ubiquitin ligases and PTEN.
Song MS; Pandolfi PP
Semin Cancer Biol; 2022 Oct; 85():43-51. PubMed ID: 34129913
[TBL] [Abstract][Full Text] [Related]
6. WWP1 Gain-of-Function Inactivation of PTEN in Cancer Predisposition.
Lee YR; Yehia L; Kishikawa T; Ni Y; Leach B; Zhang J; Panch N; Liu J; Wei W; Eng C; Pandolfi PP
N Engl J Med; 2020 May; 382(22):2103-2116. PubMed ID: 32459922
[TBL] [Abstract][Full Text] [Related]
7. The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4.
Ahn Y; Hwang CY; Lee SR; Kwon KS; Lee C
Biochem J; 2008 Jun; 412(2):331-8. PubMed ID: 18307411
[TBL] [Abstract][Full Text] [Related]
8. Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 To Regulate Egress.
Han Z; Sagum CA; Takizawa F; Ruthel G; Berry CT; Kong J; Sunyer JO; Freedman BD; Bedford MT; Sidhu SS; Sudol M; Harty RN
J Virol; 2017 Oct; 91(20):. PubMed ID: 28768865
[TBL] [Abstract][Full Text] [Related]
9. WWP1 as a potential tumor oncogene regulates PTEN-Akt signaling pathway in human gastric carcinoma.
Zhang L; Wu Z; Ma Z; Liu H; Wu Y; Zhang Q
Tumour Biol; 2015 Feb; 36(2):787-98. PubMed ID: 25293520
[TBL] [Abstract][Full Text] [Related]
10. WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis.
Li Y; Zhou Z; Chen C
Cell Death Differ; 2008 Dec; 15(12):1941-51. PubMed ID: 18806757
[TBL] [Abstract][Full Text] [Related]
11. Functional Characterization of a WWP1/Tiul1 Tumor-derived Mutant Reveals a Paradigm of Its Constitutive Activation in Human Cancer.
Courivaud T; Ferrand N; Elkhattouti A; Kumar S; Levy L; Ferrigno O; Atfi A; Prunier C
J Biol Chem; 2015 Aug; 290(34):21007-21018. PubMed ID: 26152726
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of cIAP1 as a strategy for targeting c-MYC-driven oncogenic activity.
Li H; Fang Y; Niu C; Cao H; Mi T; Zhu H; Yuan J; Zhu J
Proc Natl Acad Sci U S A; 2018 Oct; 115(40):E9317-E9324. PubMed ID: 30181285
[TBL] [Abstract][Full Text] [Related]
13. Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis.
Berger PL; Frank SB; Schulz VV; Nollet EA; Edick MJ; Holly B; Chang TT; Hostetter G; Kim S; Miranti CK
Cancer Res; 2014 Jun; 74(12):3357-68. PubMed ID: 24762396
[TBL] [Abstract][Full Text] [Related]
14. Functional significance and therapeutic implication of ring-type E3 ligases in colorectal cancer.
Liu L; Wong CC; Gong B; Yu J
Oncogene; 2018 Jan; 37(2):148-159. PubMed ID: 28925398
[TBL] [Abstract][Full Text] [Related]
15. The zinc-finger protein ZCCHC2 suppresses retinoblastoma tumorigenesis by inhibiting HectH9-mediated K63-linked polyubiquitination and activation of c-Myc.
Dai H; Yan M; Li Y
Biochem Biophys Res Commun; 2020 Jan; 521(2):533-538. PubMed ID: 31677785
[TBL] [Abstract][Full Text] [Related]
16. WWP1 E3 ligase at the crossroads of health and disease.
Behera A; Reddy ABM
Cell Death Dis; 2023 Dec; 14(12):853. PubMed ID: 38129384
[TBL] [Abstract][Full Text] [Related]
17. WW Domain-Containing E3 Ubiquitin Protein Ligase 1: A Self-Disciplined Oncoprotein.
Kuang L; Jiang Y; Li C; Jiang Y
Front Cell Dev Biol; 2021; 9():757493. PubMed ID: 34712671
[TBL] [Abstract][Full Text] [Related]
18. PTEN: a default gate-keeping tumor suppressor with a versatile tail.
Wang X; Jiang X
Cell Res; 2008 Aug; 18(8):807-16. PubMed ID: 18626510
[TBL] [Abstract][Full Text] [Related]
19. The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in multiple myeloma.
Crawford LJ; Campbell DC; Morgan JJ; Lawson MA; Down JM; Chauhan D; McAvera RM; Morris TC; Hamilton C; Krishnan A; Rajalingam K; Chantry AD; Irvine AE
Oncogene; 2020 Jul; 39(27):5001-5014. PubMed ID: 32523091
[TBL] [Abstract][Full Text] [Related]
20. A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases.
Wang Z; Liu Z; Chen X; Li J; Yao W; Huang S; Gu A; Lei QY; Mao Y; Wen W
Nat Commun; 2019 Jul; 10(1):3162. PubMed ID: 31320636
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]