BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

289 related articles for article (PubMed ID: 31100067)

  • 1. Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in KrasG12D mice.
    Hao F; Xu Q; Wang J; Yu S; Chang HH; Sinnett-Smith J; Eibl G; Rozengurt E
    PLoS One; 2019; 14(5):e0216603. PubMed ID: 31100067
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells.
    Hao F; Xu Q; Zhao Y; Stevens JV; Young SH; Sinnett-Smith J; Rozengurt E
    Mol Cancer Res; 2017 Jul; 15(7):929-941. PubMed ID: 28360038
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lipophilic Statins Inhibit YAP Nuclear Localization, Coactivator Activity, and Migration in Response to Ligation of HLA Class I Molecules in Endothelial Cells: Role of YAP Multisite Phosphorylation.
    Anwar T; Sinnett-Smith J; Jin YP; Reed EF; Rozengurt E
    J Immunol; 2023 Apr; 210(8):1134-1145. PubMed ID: 36881871
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Central role of Yes-associated protein and WW-domain-containing transcriptional co-activator with PDZ-binding motif in pancreatic cancer development.
    Rozengurt E; Eibl G
    World J Gastroenterol; 2019 Apr; 25(15):1797-1816. PubMed ID: 31057295
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Atorvastatin inhibits pancreatic carcinogenesis and increases survival in LSL-KrasG12D-LSL-Trp53R172H-Pdx1-Cre mice.
    Liao J; Chung YT; Yang AL; Zhang M; Li H; Zhang W; Yan L; Yang GY
    Mol Carcinog; 2013 Sep; 52(9):739-50. PubMed ID: 22549877
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A combinatorial strategy using YAP and pan-RAF inhibitors for treating KRAS-mutant pancreatic cancer.
    Zhao X; Wang X; Fang L; Lan C; Zheng X; Wang Y; Zhang Y; Han X; Liu S; Cheng K; Zhao Y; Shi J; Guo J; Hao J; Ren H; Nie G
    Cancer Lett; 2017 Aug; 402():61-70. PubMed ID: 28576749
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Verteporfin suppresses cell survival, angiogenesis and vasculogenic mimicry of pancreatic ductal adenocarcinoma via disrupting the YAP-TEAD complex.
    Wei H; Wang F; Wang Y; Li T; Xiu P; Zhong J; Sun X; Li J
    Cancer Sci; 2017 Mar; 108(3):478-487. PubMed ID: 28002618
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metformin Decreases the Incidence of Pancreatic Ductal Adenocarcinoma Promoted by Diet-induced Obesity in the Conditional KrasG12D Mouse Model.
    Chang HH; Moro A; Chou CEN; Dawson DW; French S; Schmidt AI; Sinnett-Smith J; Hao F; Hines OJ; Eibl G; Rozengurt E
    Sci Rep; 2018 Apr; 8(1):5899. PubMed ID: 29651002
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma.
    Murakami S; Shahbazian D; Surana R; Zhang W; Chen H; Graham GT; White SM; Weiner LM; Yi C
    Oncogene; 2017 Mar; 36(9):1232-1244. PubMed ID: 27546622
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level.
    Thongon N; Castiglioni I; Zucal C; Latorre E; D'Agostino V; Bauer I; Pancher M; Ballestrero A; Feldmann G; Nencioni A; Provenzani A
    Oncotarget; 2016 May; 7(18):26551-66. PubMed ID: 27034169
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lipophilic statins inhibit YAP coactivator transcriptional activity in HCC cells through Rho-mediated modulation of actin cytoskeleton.
    Benhammou JN; Qiao B; Ko A; Sinnett-Smith J; Pisegna JR; Rozengurt E
    Am J Physiol Gastrointest Liver Physiol; 2023 Sep; 325(3):G239-G250. PubMed ID: 37366601
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
    Hermann PC; Sancho P; Cañamero M; Martinelli P; Madriles F; Michl P; Gress T; de Pascual R; Gandia L; Guerra C; Barbacid M; Wagner M; Vieira CR; Aicher A; Real FX; Sainz B; Heeschen C
    Gastroenterology; 2014 Nov; 147(5):1119-33.e4. PubMed ID: 25127677
    [TBL] [Abstract][Full Text] [Related]  

  • 13. lncRNA
    Li N; Yang G; Luo L; Ling L; Wang X; Shi L; Lan J; Jia X; Zhang Q; Long Z; Liu J; Hu W; He Z; Liu H; Liu W; Zheng G
    Clin Cancer Res; 2020 Apr; 26(7):1736-1748. PubMed ID: 31831555
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma.
    Zhang W; Nandakumar N; Shi Y; Manzano M; Smith A; Graham G; Gupta S; Vietsch EE; Laughlin SZ; Wadhwa M; Chetram M; Joshi M; Wang F; Kallakury B; Toretsky J; Wellstein A; Yi C
    Sci Signal; 2014 May; 7(324):ra42. PubMed ID: 24803537
    [TBL] [Abstract][Full Text] [Related]  

  • 15. IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation.
    Garcia MN; Grasso D; Lopez-Millan MB; Hamidi T; Loncle C; Tomasini R; Lomberk G; Porteu F; Urrutia R; Iovanna JL
    J Clin Invest; 2014 Nov; 124(11):4709-22. PubMed ID: 25250570
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells.
    Gbelcová H; Rimpelová S; Knejzlík Z; Šáchová J; Kolář M; Strnad H; Repiská V; D'Acunto WC; Ruml T; Vítek L
    Lipids Health Dis; 2017 Dec; 16(1):250. PubMed ID: 29262834
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Low dosage combination treatment with metformin and simvastatin inhibits obesity-promoted pancreatic cancer development in male KrasG12D mice.
    Teper Y; Ye L; Waldron RT; Lugea A; Sun X; Sinnett-Smith J; Hines OJ; Pandol SJ; Rozengurt E; Eibl G
    Sci Rep; 2023 Sep; 13(1):16144. PubMed ID: 37752238
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Statins inhibit blastocyst formation by preventing geranylgeranylation.
    Alarcon VB; Marikawa Y
    Mol Hum Reprod; 2016 May; 22(5):350-63. PubMed ID: 26908642
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice.
    Mohammed A; Qian L; Janakiram NB; Lightfoot S; Steele VE; Rao CV
    Int J Cancer; 2012 Oct; 131(8):1951-62. PubMed ID: 22287227
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas.
    Murakami S; Nemazanyy I; White SM; Chen H; Nguyen CDK; Graham GT; Saur D; Pende M; Yi C
    Dev Cell; 2019 Oct; 51(1):113-128.e9. PubMed ID: 31447265
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.