These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 31103405)

  • 1. Structure-based drug design of novel carborane-containing nicotinamide phosphoribosyltransferase inhibitors.
    Asawa Y; Katsuragi K; Sato A; Yoshimori A; Tanuma SI; Nakamura H
    Bioorg Med Chem; 2019 Jul; 27(13):2832-2844. PubMed ID: 31103405
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural Basis of Beneficial Design for Effective Nicotinamide Phosphoribosyltransferase Inhibitors.
    Tanuma SI; Katsuragi K; Oyama T; Yoshimori A; Shibasaki Y; Asawa Y; Yamazaki H; Makino K; Okazawa M; Ogino Y; Sakamoto Y; Nomura M; Sato A; Abe H; Nakamura H; Takahashi H; Tanuma N; Uchiumi F
    Molecules; 2020 Aug; 25(16):. PubMed ID: 32785052
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure-based comparison of two NAMPT inhibitors.
    Zhang SL; Xu TY; Yang ZL; Han S; Zhao Q; Miao CY
    Acta Pharmacol Sin; 2018 Feb; 39(2):294-301. PubMed ID: 28858298
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure based design of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors from a phenotypic screen.
    Palacios DS; Meredith E; Kawanami T; Adams C; Chen X; Darsigny V; Geno E; Palermo M; Baird D; Boynton G; Busby SA; George EL; Guy C; Hewett J; Tierney L; Thigale S; Weihofen W; Wang L; White N; Yin M; Argikar UA
    Bioorg Med Chem Lett; 2018 Feb; 28(3):365-370. PubMed ID: 29275937
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Clickable prodrugs bearing potent and hydrolytically cleavable nicotinamide phosphoribosyltransferase inhibitors.
    Sadrerafi K; Mason EO; Lee MW
    Drug Des Devel Ther; 2018; 12():987-995. PubMed ID: 29731606
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of trans-3-(pyridin-3-yl)acrylamide-derived sulfamides as potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitors for the potential treatment of cancer.
    Zhang K; Ni Y; Chen J; Tu Z; Wu X; Chen D; Yao H; Jiang S
    Bioorg Med Chem Lett; 2019 Jun; 29(12):1502-1506. PubMed ID: 30992165
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors.
    Zheng X; Bauer P; Baumeister T; Buckmelter AJ; Caligiuri M; Clodfelter KH; Han B; Ho YC; Kley N; Lin J; Reynolds DJ; Sharma G; Smith CC; Wang Z; Dragovich PS; Gunzner-Toste J; Liederer BM; Ly J; O'Brien T; Oh A; Wang L; Wang W; Xiao Y; Zak M; Zhao G; Yuen PW; Bair KW
    J Med Chem; 2013 Aug; 56(16):6413-33. PubMed ID: 23859118
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
    Dragovich PS; Zhao G; Baumeister T; Bravo B; Giannetti AM; Ho YC; Hua R; Li G; Liang X; Ma X; O'Brien T; Oh A; Skelton NJ; Wang C; Wang W; Wang Y; Xiao Y; Yuen PW; Zak M; Zhao Q; Zheng X
    Bioorg Med Chem Lett; 2014 Feb; 24(3):954-62. PubMed ID: 24433859
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
    Dragovich PS; Bair KW; Baumeister T; Ho YC; Liederer BM; Liu X; Liu Y; O'Brien T; Oeh J; Sampath D; Skelton N; Wang L; Wang W; Wu H; Xiao Y; Yuen PW; Zak M; Zhang L; Zheng X
    Bioorg Med Chem Lett; 2013 Sep; 23(17):4875-85. PubMed ID: 23899614
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of novel Nicotinamide Phosphoribosyltransferase (NAMPT) inhibitors using computational approaches.
    Kesherwani M; Raghavan S; Gunasekaran K; Velmurugan D
    J Biomol Struct Dyn; 2018 Apr; 36(5):1306-1328. PubMed ID: 28514875
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors.
    Zheng X; Baumeister T; Buckmelter AJ; Caligiuri M; Clodfelter KH; Han B; Ho YC; Kley N; Lin J; Reynolds DJ; Sharma G; Smith CC; Wang Z; Dragovich PS; Oh A; Wang W; Zak M; Wang Y; Yuen PW; Bair KW
    Bioorg Med Chem Lett; 2014 Jan; 24(1):337-43. PubMed ID: 24279990
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening.
    Ozgencil F; Eren G; Ozkan Y; Guntekin-Ergun S; Cetin-Atalay R
    Bioorg Med Chem; 2020 Jan; 28(1):115217. PubMed ID: 31818629
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-activity relationship.
    Christensen MK; Erichsen KD; Olesen UH; Tjørnelund J; Fristrup P; Thougaard A; Nielsen SJ; Sehested M; Jensen PB; Loza E; Kalvinsh I; Garten A; Kiess W; Björkling F
    J Med Chem; 2013 Nov; 56(22):9071-88. PubMed ID: 24164086
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties.
    Gunzner-Toste J; Zhao G; Bauer P; Baumeister T; Buckmelter AJ; Caligiuri M; Clodfelter KH; Fu B; Han B; Ho YC; Kley N; Liang X; Liederer BM; Lin J; Mukadam S; O'Brien T; Oh A; Reynolds DJ; Sharma G; Skelton N; Smith CC; Sodhi J; Wang W; Wang Z; Xiao Y; Yuen PW; Zak M; Zhang L; Zheng X; Bair KW; Dragovich PS
    Bioorg Med Chem Lett; 2013 Jun; 23(12):3531-8. PubMed ID: 23668988
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors.
    Zheng X; Bauer P; Baumeister T; Buckmelter AJ; Caligiuri M; Clodfelter KH; Han B; Ho YC; Kley N; Lin J; Reynolds DJ; Sharma G; Smith CC; Wang Z; Dragovich PS; Oh A; Wang W; Zak M; Gunzner-Toste J; Zhao G; Yuen PW; Bair KW
    J Med Chem; 2013 Jun; 56(12):4921-37. PubMed ID: 23617784
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of benzothiophene amides as potent inhibitors of human nicotinamide phosphoribosyltransferase.
    Chen W; Dong G; He S; Xu T; Wang X; Liu N; Zhang W; Miao C; Sheng C
    Bioorg Med Chem Lett; 2016 Feb; 26(3):765-768. PubMed ID: 26755394
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
    Zheng X; Bair KW; Bauer P; Baumeister T; Bowman KK; Buckmelter AJ; Caligiuri M; Clodfelter KH; Feng Y; Han B; Ho YC; Kley N; Li H; Liang X; Liederer BM; Lin J; Ly J; O'Brien T; Oeh J; Oh A; Reynolds DJ; Sampath D; Sharma G; Skelton N; Smith CC; Tremayne J; Wang L; Wang W; Wang Z; Wu H; Wu J; Xiao Y; Yang G; Yuen PW; Zak M; Dragovich PS
    Bioorg Med Chem Lett; 2013 Oct; 23(20):5488-97. PubMed ID: 24021463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of a novel nicotinamide phosphoribosyl transferase (NAMPT) inhibitor via in silico screening.
    Takeuchi M; Niimi T; Masumoto M; Orita M; Yokota H; Yamamoto T
    Biol Pharm Bull; 2014; 37(1):31-6. PubMed ID: 24389478
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fragment-based discovery of a potent NAMPT inhibitor.
    Korepanova A; Longenecker KL; Pratt SD; Panchal SC; Clark RF; Lake M; Gopalakrishnan SM; Raich D; Sun C; Petros AM
    Bioorg Med Chem Lett; 2018 Feb; 28(3):437-440. PubMed ID: 29287958
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors.
    Galli U; Travelli C; Massarotti A; Fakhfouri G; Rahimian R; Tron GC; Genazzani AA
    J Med Chem; 2013 Aug; 56(16):6279-96. PubMed ID: 23679915
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.