BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 31103446)

  • 1. Design, synthesis and biological evaluation of benzimidazole derivatives as novel human Pin1 inhibitors.
    Ma T; Huang M; Li A; Zhao F; Li D; Liu D; Zhao L
    Bioorg Med Chem Lett; 2019 Jul; 29(14):1859-1863. PubMed ID: 31103446
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-Based Design of Novel Benzimidazole Derivatives as Pin1 Inhibitors.
    Wang S; Guan L; Zang J; Xing K; Zhang J; Liu D; Zhao L
    Molecules; 2019 Mar; 24(7):. PubMed ID: 30934730
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of pyrimidine derivatives as novel human Pin1 inhibitors.
    Cui G; Jin J; Chen H; Cao R; Chen X; Xu B
    Bioorg Med Chem; 2018 May; 26(8):2186-2197. PubMed ID: 29576270
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and Pin1 inhibitory activity of thiazole derivatives.
    Zhao H; Cui G; Jin J; Chen X; Xu B
    Bioorg Med Chem; 2016 Nov; 24(22):5911-5920. PubMed ID: 27692510
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Conjugates of 18β-glycyrrhetinic acid derivatives with 3-(1H-benzo[d]imidazol-2-yl)propanoic acid as Pin1 inhibitors displaying anti-prostate cancer ability.
    Li K; Ma T; Cai J; Huang M; Guo H; Zhou D; Luan S; Yang J; Liu D; Jing Y; Zhao L
    Bioorg Med Chem; 2017 Oct; 25(20):5441-5451. PubMed ID: 28838831
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, state-of-the-art NMR-binding and molecular modeling study of new benzimidazole core derivatives as Pin1 inhibitors: Targeting breast cancer.
    Nashaat S; Henen MA; El-Messery SM; Eisa H
    Bioorg Med Chem; 2020 Jun; 28(11):115495. PubMed ID: 32307260
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of novel thiazole-based derivatives as human Pin1 inhibitors.
    Du L; Wang X; Cui G; Xu B
    Bioorg Med Chem; 2021 Jan; 29():115878. PubMed ID: 33246256
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of 4,6-bis(benzyloxy)-3-phenylbenzofuran as a novel Pin1 inhibitor to suppress hepatocellular carcinoma via upregulating microRNA biogenesis.
    Fan X; He H; Li J; Luo G; Zheng Y; Zhou JK; He J; Pu W; Zhao Y
    Bioorg Med Chem; 2019 Jun; 27(11):2235-2244. PubMed ID: 31027708
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An irreversible inhibitor of peptidyl-prolyl cis/trans isomerase Pin1 and evaluation of cytotoxicity.
    Ieda N; Itoh K; Inoue Y; Izumiya Y; Kawaguchi M; Miyata N; Nakagawa H
    Bioorg Med Chem Lett; 2019 Feb; 29(3):353-356. PubMed ID: 30585173
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and biological evaluation of ring A modified 11-keto-boswellic acid derivatives as Pin1 inhibitors with remarkable anti-prostate cancer activity.
    Huang M; Li A; Zhao F; Xie X; Li K; Jing Y; Liu D; Zhao L
    Bioorg Med Chem Lett; 2018 Oct; 28(19):3187-3193. PubMed ID: 30153964
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Design, synthesis and biological evaluation of novel diaryl ethers bearing a pyrimidine motif as human Pin1 inhibitors].
    Xi YY; Jin J; Sun Y; Chen XG; Song HR; Xu BL
    Yao Xue Xue Bao; 2013 Aug; 48(8):1266-72. PubMed ID: 24187834
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1).
    Liu L; Zhu R; Li J; Pei Y; Wang S; Xu P; Wang M; Wen Y; Zhang H; Du D; Ding H; Jiang H; Chen K; Zhou B; Yu L; Luo C
    J Med Chem; 2022 Feb; 65(3):2174-2190. PubMed ID: 35089030
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strategy.
    Poli G; Di Stefano M; Estevez JA; Minutolo F; Granchi C; Giordano A; Parisi S; Mauceri M; Canzonieri V; Macchia M; Caligiuri I; Tuccinardi T; Rizzolio F
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):145-150. PubMed ID: 34894990
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of the novel elemonic acid derivatives as Pin1 inhibitors.
    Li X; Li L; Zhou Q; Zhang N; Zhang S; Zhao R; Liu D; Jing Y; Zhao L
    Bioorg Med Chem Lett; 2014 Dec; 24(24):5612-5615. PubMed ID: 25466185
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of novel 2-substituted 11-keto-boswellic acid heterocyclic derivatives as anti-prostate cancer agents with Pin1 inhibition ability.
    Li K; Li L; Wang S; Li X; Ma T; Liu D; Jing Y; Zhao L
    Eur J Med Chem; 2017 Jan; 126():910-919. PubMed ID: 27997878
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-guided design of alpha-amino acid-derived Pin1 inhibitors.
    Potter AJ; Ray S; Gueritz L; Nunns CL; Bryant CJ; Scrace SF; Matassova N; Baker L; Dokurno P; Robinson DA; Surgenor AE; Davis B; Murray JB; Richardson CM; Moore JD
    Bioorg Med Chem Lett; 2010 Jan; 20(2):586-90. PubMed ID: 19969456
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New Benzimidazoles Targeting Breast Cancer: Synthesis, Pin1 Inhibition, 2D NMR Binding, and Computational Studies.
    Nashaat S; Henen MA; El-Messery SM; Eisa H
    Molecules; 2022 Aug; 27(16):. PubMed ID: 36014485
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-based design of novel human Pin1 inhibitors (III): optimizing affinity beyond the phosphate recognition pocket.
    Guo C; Hou X; Dong L; Marakovits J; Greasley S; Dagostino E; Ferre R; Johnson MC; Humphries PS; Li H; Paderes GD; Piraino J; Kraynov E; Murray BW
    Bioorg Med Chem Lett; 2014 Sep; 24(17):4187-91. PubMed ID: 25091930
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of a Prenylated Flavonol Derivative as a Pin1 Inhibitor to Suppress Hepatocellular Carcinoma by Modulating MicroRNA Biogenesis.
    Zheng Y; Pu W; Li J; Shen X; Zhou Q; Fan X; Yang SY; Yu Y; Chen Q; Wang C; Wu X; Peng Y
    Chem Asian J; 2019 Jan; 14(1):130-134. PubMed ID: 30474357
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo.
    Dubiella C; Pinch BJ; Koikawa K; Zaidman D; Poon E; Manz TD; Nabet B; He S; Resnick E; Rogel A; Langer EM; Daniel CJ; Seo HS; Chen Y; Adelmant G; Sharifzadeh S; Ficarro SB; Jamin Y; Martins da Costa B; Zimmerman MW; Lian X; Kibe S; Kozono S; Doctor ZM; Browne CM; Yang A; Stoler-Barak L; Shah RB; Vangos NE; Geffken EA; Oren R; Koide E; Sidi S; Shulman Z; Wang C; Marto JA; Dhe-Paganon S; Look T; Zhou XZ; Lu KP; Sears RC; Chesler L; Gray NS; London N
    Nat Chem Biol; 2021 Sep; 17(9):954-963. PubMed ID: 33972797
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.