104 related articles for article (PubMed ID: 31107713)
1. Divalproex sodium regulates ataxin-3 translocation likely by an importin α1-dependent pathway.
Wang Z; He F; Abeditashi M; Schmidt T
Neuroreport; 2019 Aug; 30(11):760-764. PubMed ID: 31107713
[TBL] [Abstract][Full Text] [Related]
2. Divalproex sodium modulates nuclear localization of ataxin-3 and prevents cellular toxicity caused by expanded ataxin-3.
Wang ZJ; Hanet A; Weishäupl D; Martins IM; Sowa AS; Riess O; Schmidt T
CNS Neurosci Ther; 2018 May; 24(5):404-411. PubMed ID: 29318784
[TBL] [Abstract][Full Text] [Related]
3. Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3.
Sowa AS; Martin E; Martins IM; Schmidt J; Depping R; Weber JJ; Rother F; Hartmann E; Bader M; Riess O; Tricoire H; Schmidt T
Proc Natl Acad Sci U S A; 2018 Mar; 115(11):E2624-E2633. PubMed ID: 29476013
[TBL] [Abstract][Full Text] [Related]
4. Disulfiram facilitates ataxin-3 nuclear translocation and potentiates the cytotoxicity in a cell model of SCA3.
Wang Z
J Toxicol Sci; 2019; 44(8):535-542. PubMed ID: 31378764
[TBL] [Abstract][Full Text] [Related]
5. Proteotoxic stress increases nuclear localization of ataxin-3.
Reina CP; Zhong X; Pittman RN
Hum Mol Genet; 2010 Jan; 19(2):235-49. PubMed ID: 19843543
[TBL] [Abstract][Full Text] [Related]
6. Nuclear import of the thyroid hormone receptor α1 is mediated by importin 7, importin β1, and adaptor importin α1.
Roggero VR; Zhang J; Parente LE; Doshi Y; Dziedzic RC; McGregor EL; Varjabedian AD; Schad SE; Bondzi C; Allison LA
Mol Cell Endocrinol; 2016 Jan; 419():185-97. PubMed ID: 26525414
[TBL] [Abstract][Full Text] [Related]
7. Toward therapeutic targets for SCA3: Insight into the role of Machado-Joseph disease protein ataxin-3 in misfolded proteins clearance.
Li X; Liu H; Fischhaber PL; Tang TS
Prog Neurobiol; 2015 Sep; 132():34-58. PubMed ID: 26123252
[TBL] [Abstract][Full Text] [Related]
8. Ataxin-3 is translocated into the nucleus for the formation of intranuclear inclusions in normal and Machado-Joseph disease brains.
Fujigasaki H; Uchihara T; Koyano S; Iwabuchi K; Yagishita S; Makifuchi T; Nakamura A; Ishida K; Toru S; Hirai S; Ishikawa K; Tanabe T; Mizusawa H
Exp Neurol; 2000 Oct; 165(2):248-56. PubMed ID: 10993685
[TBL] [Abstract][Full Text] [Related]
9. Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro.
Chai Y; Koppenhafer SL; Shoesmith SJ; Perez MK; Paulson HL
Hum Mol Genet; 1999 Apr; 8(4):673-82. PubMed ID: 10072437
[TBL] [Abstract][Full Text] [Related]
10. CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3.
Mueller T; Breuer P; Schmitt I; Walter J; Evert BO; Wüllner U
Hum Mol Genet; 2009 Sep; 18(17):3334-43. PubMed ID: 19542537
[TBL] [Abstract][Full Text] [Related]
11. Aptamers that bind specifically to human KPNA2 (importin-α1) and efficiently interfere with nuclear transport.
Yasuhara N; Kumar PK
J Biochem; 2016 Nov; 160(5):259-268. PubMed ID: 27154959
[TBL] [Abstract][Full Text] [Related]
12. Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease.
Simões AT; Gonçalves N; Koeppen A; Déglon N; Kügler S; Duarte CB; Pereira de Almeida L
Brain; 2012 Aug; 135(Pt 8):2428-39. PubMed ID: 22843411
[TBL] [Abstract][Full Text] [Related]
13. Identification and functional dissection of localization signals within ataxin-3.
Antony PM; Mäntele S; Mollenkopf P; Boy J; Kehlenbach RH; Riess O; Schmidt T
Neurobiol Dis; 2009 Nov; 36(2):280-92. PubMed ID: 19660550
[TBL] [Abstract][Full Text] [Related]
14. [Polyglutamine-expanded ataxin-3 is degraded by autophagy].
Xiao H; Tang J; Hu Z; Tan J; Tang B; Jiang Z
Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2010 Feb; 27(1):23-8. PubMed ID: 20140862
[TBL] [Abstract][Full Text] [Related]
15. A combinatorial approach to identify calpain cleavage sites in the Machado-Joseph disease protein ataxin-3.
Weber JJ; Golla M; Guaitoli G; Wanichawan P; Hayer SN; Hauser S; Krahl AC; Nagel M; Samer S; Aronica E; Carlson CR; Schöls L; Riess O; Gloeckner CJ; Nguyen HP; Hübener-Schmid J
Brain; 2017 May; 140(5):1280-1299. PubMed ID: 28334907
[TBL] [Abstract][Full Text] [Related]
16. HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3.
Chou AH; Chen SY; Yeh TH; Weng YH; Wang HL
Neurobiol Dis; 2011 Feb; 41(2):481-8. PubMed ID: 21047555
[TBL] [Abstract][Full Text] [Related]
17. Polyglutamine-expanded ataxin-3 impairs long-term depression in Purkinje neurons of SCA3 transgenic mouse by inhibiting HAT and impairing histone acetylation.
Chou AH; Chen YL; Hu SH; Chang YM; Wang HL
Brain Res; 2014 Oct; 1583():220-9. PubMed ID: 25139423
[TBL] [Abstract][Full Text] [Related]
18. Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence.
Bichelmeier U; Schmidt T; Hübener J; Boy J; Rüttiger L; Häbig K; Poths S; Bonin M; Knipper M; Schmidt WJ; Wilbertz J; Wolburg H; Laccone F; Riess O
J Neurosci; 2007 Jul; 27(28):7418-28. PubMed ID: 17626202
[TBL] [Abstract][Full Text] [Related]
19. Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3).
Hübener J; Weber JJ; Richter C; Honold L; Weiss A; Murad F; Breuer P; Wüllner U; Bellstedt P; Paquet-Durand F; Takano J; Saido TC; Riess O; Nguyen HP
Hum Mol Genet; 2013 Feb; 22(3):508-18. PubMed ID: 23100324
[TBL] [Abstract][Full Text] [Related]
20. Analysis of the effects of importin α1 on the nuclear translocation of IL-1α in HeLa cells.
Yamada A; Wake K; Imaoka S; Motoyoshi M; Yamamoto T; Asano M
Sci Rep; 2024 Jan; 14(1):1322. PubMed ID: 38225348
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
