346 related articles for article (PubMed ID: 31107959)
1. Motor neurons from ALS patients with mutations in C9ORF72 and SOD1 exhibit distinct transcriptional landscapes.
Wong CO; Venkatachalam K
Hum Mol Genet; 2019 Aug; 28(16):2799-2810. PubMed ID: 31107959
[TBL] [Abstract][Full Text] [Related]
2. Dysregulation of AMPA receptor subunit expression in sporadic ALS post-mortem brain.
Gregory JM; Livesey MR; McDade K; Selvaraj BT; Barton SK; Chandran S; Smith C
J Pathol; 2020 Jan; 250(1):67-78. PubMed ID: 31579943
[TBL] [Abstract][Full Text] [Related]
3. Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations.
Bursch F; Kalmbach N; Naujock M; Staege S; Eggenschwiler R; Abo-Rady M; Japtok J; Guo W; Hensel N; Reinhardt P; Boeckers TM; Cantz T; Sterneckert J; Van Den Bosch L; Hermann A; Petri S; Wegner F
Hum Mol Genet; 2019 Sep; 28(17):2835-2850. PubMed ID: 31108504
[TBL] [Abstract][Full Text] [Related]
4. Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity.
Birger A; Ben-Dor I; Ottolenghi M; Turetsky T; Gil Y; Sweetat S; Perez L; Belzer V; Casden N; Steiner D; Izrael M; Galun E; Feldman E; Behar O; Reubinoff B
EBioMedicine; 2019 Dec; 50():274-289. PubMed ID: 31787569
[TBL] [Abstract][Full Text] [Related]
5. Downstream Effects of Mutations in
Dash BP; Freischmidt A; Weishaupt JH; Hermann A
Int J Mol Sci; 2022 Aug; 23(17):. PubMed ID: 36077049
[TBL] [Abstract][Full Text] [Related]
6. Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion.
Sareen D; O'Rourke JG; Meera P; Muhammad AK; Grant S; Simpkinson M; Bell S; Carmona S; Ornelas L; Sahabian A; Gendron T; Petrucelli L; Baughn M; Ravits J; Harms MB; Rigo F; Bennett CF; Otis TS; Svendsen CN; Baloh RH
Sci Transl Med; 2013 Oct; 5(208):208ra149. PubMed ID: 24154603
[TBL] [Abstract][Full Text] [Related]
7. Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism.
Ferraiuolo L; Meyer K; Sherwood TW; Vick J; Likhite S; Frakes A; Miranda CJ; Braun L; Heath PR; Pineda R; Beattie CE; Shaw PJ; Askwith CC; McTigue D; Kaspar BK
Proc Natl Acad Sci U S A; 2016 Oct; 113(42):E6496-E6505. PubMed ID: 27688759
[TBL] [Abstract][Full Text] [Related]
8. From Mouse Models to Human Disease: An Approach for Amyotrophic Lateral Sclerosis.
Alrafiah AR
In Vivo; 2018; 32(5):983-998. PubMed ID: 30150420
[TBL] [Abstract][Full Text] [Related]
9. Single-cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS iPSC-derived motor neurons.
Namboori SC; Thomas P; Ames R; Hawkins S; Garrett LO; Willis CRG; Rosa A; Stanton LW; Bhinge A
Stem Cell Reports; 2021 Dec; 16(12):3020-3035. PubMed ID: 34767750
[TBL] [Abstract][Full Text] [Related]
10. Multiomics and machine-learning identify novel transcriptional and mutational signatures in amyotrophic lateral sclerosis.
Catanese A; Rajkumar S; Sommer D; Masrori P; Hersmus N; Van Damme P; Witzel S; Ludolph A; Ho R; Boeckers TM; Mulaw M
Brain; 2023 Sep; 146(9):3770-3782. PubMed ID: 36883643
[TBL] [Abstract][Full Text] [Related]
11. DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations.
Kim BW; Jeong YE; Wong M; Martin LJ
Acta Neuropathol Commun; 2020 Jan; 8(1):7. PubMed ID: 32005289
[TBL] [Abstract][Full Text] [Related]
12. Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD.
Dafinca R; Barbagallo P; Farrimond L; Candalija A; Scaber J; Ababneh NA; Sathyaprakash C; Vowles J; Cowley SA; Talbot K
Stem Cell Reports; 2020 May; 14(5):892-908. PubMed ID: 32330447
[TBL] [Abstract][Full Text] [Related]
13. Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.
Ting HC; Yang HI; Harn HJ; Chiu IM; Su HL; Li X; Chen MF; Ho TJ; Liu CA; Tsai YJ; Chiou TW; Lin SZ; Chang CY
Cells; 2021 Oct; 10(10):. PubMed ID: 34685754
[TBL] [Abstract][Full Text] [Related]
14. [Familial Amyotrophic Lateral Sclerosis].
Suzuki N; Nishiyama A; Kato M; Warita H; Aoki M
Brain Nerve; 2019 Nov; 71(11):1169-1181. PubMed ID: 31722303
[TBL] [Abstract][Full Text] [Related]
15. Mutant C9orf72 human iPSC-derived astrocytes cause non-cell autonomous motor neuron pathophysiology.
Zhao C; Devlin AC; Chouhan AK; Selvaraj BT; Stavrou M; Burr K; Brivio V; He X; Mehta AR; Story D; Shaw CE; Dando O; Hardingham GE; Miles GB; Chandran S
Glia; 2020 May; 68(5):1046-1064. PubMed ID: 31841614
[TBL] [Abstract][Full Text] [Related]
16. Induced pluripotent stem cell-derived motor neurons from amyotrophic lateral sclerosis (ALS) patients carrying different superoxide dismutase 1 mutations recapitulate pathological features of ALS.
Liu WC; Liu N; Wang Y; Huang C; Li YF; Wang H; Li XG; Deng M
Chin Med J (Engl); 2021 Oct; 134(20):2457-2464. PubMed ID: 34669638
[TBL] [Abstract][Full Text] [Related]
17. Genetic analysis of the SOD1 and C9ORF72 genes in Hungarian patients with amyotrophic lateral sclerosis.
Tripolszki K; Csányi B; Nagy D; Ratti A; Tiloca C; Silani V; Kereszty É; Török N; Vécsei L; Engelhardt JI; Klivényi P; Nagy N; Széll M
Neurobiol Aging; 2017 May; 53():195.e1-195.e5. PubMed ID: 28222900
[TBL] [Abstract][Full Text] [Related]
18. The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.
Imamura K; Izumi Y; Watanabe A; Tsukita K; Woltjen K; Yamamoto T; Hotta A; Kondo T; Kitaoka S; Ohta A; Tanaka A; Watanabe D; Morita M; Takuma H; Tamaoka A; Kunath T; Wray S; Furuya H; Era T; Makioka K; Okamoto K; Fujisawa T; Nishitoh H; Homma K; Ichijo H; Julien JP; Obata N; Hosokawa M; Akiyama H; Kaneko S; Ayaki T; Ito H; Kaji R; Takahashi R; Yamanaka S; Inoue H
Sci Transl Med; 2017 May; 9(391):. PubMed ID: 28539470
[TBL] [Abstract][Full Text] [Related]
19. Misfolded SOD1 inclusions in patients with mutations in
Forsberg K; Graffmo K; Pakkenberg B; Weber M; Nielsen M; Marklund S; Brännström T; Andersen PM
J Neurol Neurosurg Psychiatry; 2019 Aug; 90(8):861-869. PubMed ID: 30992335
[TBL] [Abstract][Full Text] [Related]
20. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]