BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

312 related articles for article (PubMed ID: 31112550)

  • 1. Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR.
    Zhang X; Chen W; Gao Q; Yang J; Yan X; Zhao H; Su L; Yang M; Gao C; Yao Y; Inoki K; Li D; Shao R; Wang S; Sahoo N; Kudo F; Eguchi T; Ruan B; Xu H
    PLoS Biol; 2019 May; 17(5):e3000252. PubMed ID: 31112550
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation.
    Wang W; Gao Q; Yang M; Zhang X; Yu L; Lawas M; Li X; Bryant-Genevier M; Southall NT; Marugan J; Ferrer M; Xu H
    Proc Natl Acad Sci U S A; 2015 Mar; 112(11):E1373-81. PubMed ID: 25733853
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sulforaphane Activates a lysosome-dependent transcriptional program to mitigate oxidative stress.
    Li D; Shao R; Wang N; Zhou N; Du K; Shi J; Wang Y; Zhao Z; Ye X; Zhang X; Xu H
    Autophagy; 2021 Apr; 17(4):872-887. PubMed ID: 32138578
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [The new target of Rapamycin: lysosomal calcium channel TRPML1].
    Li Q; Cai WJ; Ji YH; Feng XH
    Sheng Li Xue Bao; 2021 Feb; 73(1):137-142. PubMed ID: 33665668
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MCOLN1 is a ROS sensor in lysosomes that regulates autophagy.
    Zhang X; Cheng X; Yu L; Yang J; Calvo R; Patnaik S; Hu X; Gao Q; Yang M; Lawas M; Delling M; Marugan J; Ferrer M; Xu H
    Nat Commun; 2016 Jun; 7():12109. PubMed ID: 27357649
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis.
    Wang S; Ni HM; Chao X; Wang H; Bridges B; Kumer S; Schmitt T; Mareninova O; Gukovskaya A; De Lisle RC; Ballabio A; Pacher P; Ding WX
    Autophagy; 2019 Nov; 15(11):1954-1969. PubMed ID: 30894069
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The inhibition of TRPML1/TFEB leads to lysosomal biogenesis disorder, contributes to developmental fluoride neurotoxicity.
    Zhang J; Tang Y; Hu Z; Xu W; Ma Y; Xu P; Xing H; Niu Q
    Ecotoxicol Environ Saf; 2023 Jan; 250():114511. PubMed ID: 36608573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion.
    Zhou J; Tan SH; Nicolas V; Bauvy C; Yang ND; Zhang J; Xue Y; Codogno P; Shen HM
    Cell Res; 2013 Apr; 23(4):508-23. PubMed ID: 23337583
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
    Rusmini P; Cortese K; Crippa V; Cristofani R; Cicardi ME; Ferrari V; Vezzoli G; Tedesco B; Meroni M; Messi E; Piccolella M; Galbiati M; Garrè M; Morelli E; Vaccari T; Poletti A
    Autophagy; 2019 Apr; 15(4):631-651. PubMed ID: 30335591
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition.
    Song JX; Sun YR; Peluso I; Zeng Y; Yu X; Lu JH; Xu Z; Wang MZ; Liu LF; Huang YY; Chen LL; Durairajan SS; Zhang HJ; Zhou B; Zhang HQ; Lu A; Ballabio A; Medina DL; Guo Z; Li M
    Autophagy; 2016 Aug; 12(8):1372-89. PubMed ID: 27172265
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Curcumin targets the TFEB-lysosome pathway for induction of autophagy.
    Zhang J; Wang J; Xu J; Lu Y; Jiang J; Wang L; Shen HM; Xia D
    Oncotarget; 2016 Nov; 7(46):75659-75671. PubMed ID: 27689333
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis.
    Fernandez-Mosquera L; Yambire KF; Couto R; Pereyra L; Pabis K; Ponsford AH; Diogo CV; Stagi M; Milosevic I; Raimundo N
    Autophagy; 2019 Sep; 15(9):1572-1591. PubMed ID: 30917721
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Giant Cellular Vacuoles Induced by Rare Earth Oxide Nanoparticles are Abnormally Enlarged Endo/Lysosomes and Promote mTOR-Dependent TFEB Nucleus Translocation.
    Lin J; Shi SS; Zhang JQ; Zhang YJ; Zhang L; Liu Y; Jin PP; Wei PF; Shi RH; Zhou W; Wen LP
    Small; 2016 Nov; 12(41):5759-5768. PubMed ID: 27593892
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer's disease models.
    Guan XJ; Deng ZQ; Liu J; Su CF; Tong BC; Zhu Z; Sreenivasmurthy SG; Kan YX; Lu KJ; Chu CP; Pi RB; Cheung KH; Iyaswamy A; Song JX; Li M
    Acta Pharmacol Sin; 2024 May; 45(5):900-913. PubMed ID: 38225393
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TRPML1-/TFEB-Dependent Regulation of Lysosomal Exocytosis.
    Di Paola S; Medina DL
    Methods Mol Biol; 2019; 1925():143-144. PubMed ID: 30674023
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The mucolipidosis IV Ca2+ channel TRPML1 (MCOLN1) is regulated by the TOR kinase.
    Onyenwoke RU; Sexton JZ; Yan F; Díaz MC; Forsberg LJ; Major MB; Brenman JE
    Biochem J; 2015 Sep; 470(3):331-42. PubMed ID: 26195823
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB.
    Medina DL; Di Paola S; Peluso I; Armani A; De Stefani D; Venditti R; Montefusco S; Scotto-Rosato A; Prezioso C; Forrester A; Settembre C; Wang W; Gao Q; Xu H; Sandri M; Rizzuto R; De Matteis MA; Ballabio A
    Nat Cell Biol; 2015 Mar; 17(3):288-99. PubMed ID: 25720963
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance.
    Tedeschi V; Petrozziello T; Sisalli MJ; Boscia F; Canzoniero LMT; Secondo A
    Sci Rep; 2019 Jul; 9(1):10743. PubMed ID: 31341250
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cu(II) disrupts autophagy-mediated lysosomal degradation of oligomeric Aβ in microglia via mTOR-TFEB pathway.
    Tan X; Guan H; Yang Y; Luo S; Hou L; Chen H; Li J
    Toxicol Appl Pharmacol; 2020 Aug; 401():115090. PubMed ID: 32512069
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SMURF1 controls the PPP3/calcineurin complex and TFEB at a regulatory node for lysosomal biogenesis.
    Xia Q; Zheng H; Li Y; Xu W; Wu C; Xu J; Li S; Zhang L; Dong L
    Autophagy; 2024 Apr; 20(4):735-751. PubMed ID: 37909662
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.