433 related articles for article (PubMed ID: 31113487)
1. APOE genotype and sex affect microglial interactions with plaques in Alzheimer's disease mice.
Stephen TL; Cacciottolo M; Balu D; Morgan TE; LaDu MJ; Finch CE; Pike CJ
Acta Neuropathol Commun; 2019 May; 7(1):82. PubMed ID: 31113487
[TBL] [Abstract][Full Text] [Related]
2. Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice.
Fitz NF; Wolfe CM; Playso BE; Biedrzycki RJ; Lu Y; Nam KN; Lefterov I; Koldamova R
Mol Neurodegener; 2020 Jul; 15(1):41. PubMed ID: 32703241
[TBL] [Abstract][Full Text] [Related]
3. Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease.
Liu CC; Wang N; Chen Y; Inoue Y; Shue F; Ren Y; Wang M; Qiao W; Ikezu TC; Li Z; Zhao J; Martens Y; Doss SV; Rosenberg CL; Jeevaratnam S; Jia L; Raulin AC; Qi F; Zhu Y; Alnobani A; Knight J; Chen Y; Linares C; Kurti A; Fryer JD; Zhang B; Wu LJ; Kim BYS; Bu G
Nat Immunol; 2023 Nov; 24(11):1854-1866. PubMed ID: 37857825
[TBL] [Abstract][Full Text] [Related]
4. Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease.
Fitz NF; Nam KN; Wolfe CM; Letronne F; Playso BE; Iordanova BE; Kozai TDY; Biedrzycki RJ; Kagan VE; Tyurina YY; Han X; Lefterov I; Koldamova R
Nat Commun; 2021 Jun; 12(1):3416. PubMed ID: 34099706
[TBL] [Abstract][Full Text] [Related]
5. Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition.
Rodriguez GA; Tai LM; LaDu MJ; Rebeck GW
J Neuroinflammation; 2014 Jun; 11():111. PubMed ID: 24948358
[TBL] [Abstract][Full Text] [Related]
6. APOE genotype and biological sex regulate astroglial interactions with amyloid plaques in Alzheimer's disease mice.
Stephen TL; Breningstall B; Suresh S; McGill CJ; Pike CJ
J Neuroinflammation; 2022 Dec; 19(1):286. PubMed ID: 36457019
[TBL] [Abstract][Full Text] [Related]
7. Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis.
Mahan TE; Wang C; Bao X; Choudhury A; Ulrich JD; Holtzman DM
Mol Neurodegener; 2022 Feb; 17(1):13. PubMed ID: 35109920
[TBL] [Abstract][Full Text] [Related]
8. APOE4 genotype and aging impair injury-induced microglial behavior in brain slices, including toward Aβ, through P2RY12.
Sepulveda J; Kim JY; Binder J; Vicini S; Rebeck GW
Mol Neurodegener; 2024 Mar; 19(1):24. PubMed ID: 38468308
[TBL] [Abstract][Full Text] [Related]
9. Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Parhizkar S; Arzberger T; Brendel M; Kleinberger G; Deussing M; Focke C; Nuscher B; Xiong M; Ghasemigharagoz A; Katzmarski N; Krasemann S; Lichtenthaler SF; Müller SA; Colombo A; Monasor LS; Tahirovic S; Herms J; Willem M; Pettkus N; Butovsky O; Bartenstein P; Edbauer D; Rominger A; Ertürk A; Grathwohl SA; Neher JJ; Holtzman DM; Meyer-Luehmann M; Haass C
Nat Neurosci; 2019 Feb; 22(2):191-204. PubMed ID: 30617257
[TBL] [Abstract][Full Text] [Related]
10. The effect of amyloid on microglia-neuron interactions before plaque onset occurs independently of TREM2 in a mouse model of Alzheimer's disease.
von Saucken VE; Jay TR; Landreth GE
Neurobiol Dis; 2020 Nov; 145():105072. PubMed ID: 32890775
[TBL] [Abstract][Full Text] [Related]
11. Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
Meilandt WJ; Ngu H; Gogineni A; Lalehzadeh G; Lee SH; Srinivasan K; Imperio J; Wu T; Weber M; Kruse AJ; Stark KL; Chan P; Kwong M; Modrusan Z; Friedman BA; Elstrott J; Foreman O; Easton A; Sheng M; Hansen DV
J Neurosci; 2020 Feb; 40(9):1956-1974. PubMed ID: 31980586
[No Abstract] [Full Text] [Related]
12. APOE modulates the effect of estrogen therapy on Aβ accumulation EFAD-Tg mice.
Kunzler J; Youmans KL; Yu C; Ladu MJ; Tai LM
Neurosci Lett; 2014 Feb; 560():131-6. PubMed ID: 24368217
[TBL] [Abstract][Full Text] [Related]
13. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
Huang YA; Zhou B; Nabet AM; Wernig M; Südhof TC
J Neurosci; 2019 Sep; 39(37):7408-7427. PubMed ID: 31331998
[TBL] [Abstract][Full Text] [Related]
14. Human apolipoprotein E redistributes fibrillar amyloid deposition in Tg-SwDI mice.
Xu F; Vitek MP; Colton CA; Previti ML; Gharkholonarehe N; Davis J; Van Nostrand WE
J Neurosci; 2008 May; 28(20):5312-20. PubMed ID: 18480287
[TBL] [Abstract][Full Text] [Related]
15. Epidermal growth factor prevents APOE4 and amyloid-beta-induced cognitive and cerebrovascular deficits in female mice.
Thomas R; Zuchowska P; Morris AW; Marottoli FM; Sunny S; Deaton R; Gann PH; Tai LM
Acta Neuropathol Commun; 2016 Oct; 4(1):111. PubMed ID: 27788676
[TBL] [Abstract][Full Text] [Related]
16. Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.
Buttini M; Yu GQ; Shockley K; Huang Y; Jones B; Masliah E; Mallory M; Yeo T; Longo FM; Mucke L
J Neurosci; 2002 Dec; 22(24):10539-48. PubMed ID: 12486146
[TBL] [Abstract][Full Text] [Related]
17. Investigation of pathology, expression and proteomic profiles in human TREM2 variant postmortem brains with and without Alzheimer's disease.
Toomey CE; Heywood W; Benson BC; Packham G; Mills K; Lashley T
Brain Pathol; 2020 Jul; 30(4):794-810. PubMed ID: 32267026
[TBL] [Abstract][Full Text] [Related]
18. Different mechanisms of apolipoprotein E isoform-dependent modulation of prostaglandin E2 production and triggering receptor expressed on myeloid cells 2 (TREM2) expression after innate immune activation of microglia.
Li X; Montine KS; Keene CD; Montine TJ
FASEB J; 2015 May; 29(5):1754-62. PubMed ID: 25593125
[TBL] [Abstract][Full Text] [Related]
19. Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation.
Liao F; Li A; Xiong M; Bien-Ly N; Jiang H; Zhang Y; Finn MB; Hoyle R; Keyser J; Lefton KB; Robinson GO; Serrano JR; Silverman AP; Guo JL; Getz J; Henne K; Leyns CE; Gallardo G; Ulrich JD; Sullivan PM; Lerner EP; Hudry E; Sweeney ZK; Dennis MS; Hyman BT; Watts RJ; Holtzman DM
J Clin Invest; 2018 May; 128(5):2144-2155. PubMed ID: 29600961
[TBL] [Abstract][Full Text] [Related]
20. Obesity Accelerates Alzheimer-Related Pathology in
Moser VA; Pike CJ
eNeuro; 2017; 4(3):. PubMed ID: 28612048
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]