193 related articles for article (PubMed ID: 31113867)
1. Mitochondrially targeted cytochrome P450 2D6 is involved in monomethylamine-induced neuronal damage in mouse models.
Chattopadhyay M; Chowdhury AR; Feng T; Assenmacher CA; Radaelli E; Guengerich FP; Avadhani NG
J Biol Chem; 2019 Jun; 294(26):10336-10348. PubMed ID: 31113867
[TBL] [Abstract][Full Text] [Related]
2. Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease.
Bajpai P; Sangar MC; Singh S; Tang W; Bansal S; Chowdhury G; Cheng Q; Fang JK; Martin MV; Guengerich FP; Avadhani NG
J Biol Chem; 2013 Feb; 288(6):4436-51. PubMed ID: 23258538
[TBL] [Abstract][Full Text] [Related]
3. Cytochrome P450 2D6 enzyme neuroprotects against 1-methyl-4-phenylpyridinium toxicity in SH-SY5Y neuronal cells.
Mann A; Tyndale RF
Eur J Neurosci; 2010 Apr; 31(7):1185-93. PubMed ID: 20345925
[TBL] [Abstract][Full Text] [Related]
4. Comparative aromatic hydroxylation and N-demethylation of MPTP neurotoxin and its analogs, N-methylated beta-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6.
Herraiz T; Guillén H; Arán VJ; Idle JR; Gonzalez FJ
Toxicol Appl Pharmacol; 2006 Nov; 216(3):387-98. PubMed ID: 16870220
[TBL] [Abstract][Full Text] [Related]
5. The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.
Singh S; Singh K; Patel DK; Singh C; Nath C; Singh VK; Singh RK; Singh MP
Rejuvenation Res; 2009 Jun; 12(3):185-97. PubMed ID: 19594327
[TBL] [Abstract][Full Text] [Related]
6. Modulation of mitochondrial phenotypes by endurance exercise contributes to neuroprotection against a MPTP-induced animal model of PD.
Jang Y; Kwon I; Song W; Cosio-Lima LM; Taylor S; Lee Y
Life Sci; 2018 Sep; 209():455-465. PubMed ID: 30144449
[TBL] [Abstract][Full Text] [Related]
7. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is N-demethylated by cytochromes P450 2D6, 1A2 and 3A4--implications for susceptibility to Parkinson's disease.
Coleman T; Ellis SW; Martin IJ; Lennard MS; Tucker GT
J Pharmacol Exp Ther; 1996 May; 277(2):685-90. PubMed ID: 8627546
[TBL] [Abstract][Full Text] [Related]
8. [Metabolic activation of azaheterocyclics induced dopaminergic toxicity: possible candidate neurotoxins underlying idiopathic Parkinson's disease].
Matsubara K
Nihon Hoigaku Zasshi; 1998 Oct; 52(5):301-5. PubMed ID: 10077975
[TBL] [Abstract][Full Text] [Related]
9. Neuroprotective effects of 5-(4-hydroxy-3-dimethoxybenzylidene)-thiazolidinone in MPTP induced Parkinsonism model in mice.
Ren Z; Yang N; Ji C; Zheng J; Wang T; Liu Y; Zuo P
Neuropharmacology; 2015 Jun; 93():209-18. PubMed ID: 25680233
[TBL] [Abstract][Full Text] [Related]
10. Overexpression of TFAM, NRF-1 and myr-AKT protects the MPP(+)-induced mitochondrial dysfunctions in neuronal cells.
Piao Y; Kim HG; Oh MS; Pak YK
Biochim Biophys Acta; 2012 May; 1820(5):577-85. PubMed ID: 21856379
[TBL] [Abstract][Full Text] [Related]
11. Ganoderma lucidum extract ameliorates MPTP-induced parkinsonism and protects dopaminergic neurons from oxidative stress via regulating mitochondrial function, autophagy, and apoptosis.
Ren ZL; Wang CD; Wang T; Ding H; Zhou M; Yang N; Liu YY; Chan P
Acta Pharmacol Sin; 2019 Apr; 40(4):441-450. PubMed ID: 29991712
[TBL] [Abstract][Full Text] [Related]
12. The Essential Role of Drp1 and Its Regulation by S-Nitrosylation of Parkin in Dopaminergic Neurodegeneration: Implications for Parkinson's Disease.
Zhang Z; Liu L; Jiang X; Zhai S; Xing D
Antioxid Redox Signal; 2016 Oct; 25(11):609-622. PubMed ID: 27267045
[TBL] [Abstract][Full Text] [Related]
13. G protein-coupled estrogen receptor is involved in the neuroprotective effect of IGF-1 against MPTP/MPP
Yuan LJ; Wang XW; Wang HT; Zhang M; Sun JW; Chen WF
J Steroid Biochem Mol Biol; 2019 Sep; 192():105384. PubMed ID: 31175966
[TBL] [Abstract][Full Text] [Related]
14. Anti-apoptotic effect of modified Chunsimyeolda-tang, a traditional Korean herbal formula, on MPTP-induced neuronal cell death in a Parkinson's disease mouse model.
Li H; Park G; Bae N; Kim J; Oh MS; Yang HO
J Ethnopharmacol; 2015 Dec; 176():336-44. PubMed ID: 26593210
[TBL] [Abstract][Full Text] [Related]
15. Early signs of neuronal apoptosis in the substantia nigra pars compacta of the progressive neurodegenerative mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model of Parkinson's disease.
Novikova L; Garris BL; Garris DR; Lau YS
Neuroscience; 2006 Jun; 140(1):67-76. PubMed ID: 16533572
[TBL] [Abstract][Full Text] [Related]
16. Metabolism of MPTP by cytochrome P4502D6 and the demonstration of 2D6 mRNA in human foetal and adult brain by in situ hybridization.
Gilham DE; Cairns W; Paine MJ; Modi S; Poulsom R; Roberts GC; Wolf CR
Xenobiotica; 1997 Jan; 27(1):111-25. PubMed ID: 9041683
[TBL] [Abstract][Full Text] [Related]
17. Tristetraprolin destabilizes NOX2 mRNA and protects dopaminergic neurons from oxidative damage in Parkinson's disease.
Sun X; Zhang H; Xie L; Qian C; Ye Y; Mao H; Wang B; Zhang H; Zhang Y; He X; Zhang S
FASEB J; 2020 Nov; 34(11):15047-15061. PubMed ID: 32954540
[TBL] [Abstract][Full Text] [Related]
18. 5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole (DDO-7263), a novel Nrf2 activator targeting brain tissue, protects against MPTP-induced subacute Parkinson's disease in mice by inhibiting the NLRP3 inflammasome and protects PC12 cells against oxidative stress.
Xu LL; Wu YF; Yan F; Li CC; Dai Z; You QD; Jiang ZY; Di B
Free Radic Biol Med; 2019 Apr; 134():288-303. PubMed ID: 30615919
[TBL] [Abstract][Full Text] [Related]
19. Neurotoxin-induced pathway perturbation in human neuroblastoma SH-EP cells.
Do JH
Mol Cells; 2014 Sep; 37(9):672-84. PubMed ID: 25234470
[TBL] [Abstract][Full Text] [Related]
20. BMAL1 regulation of microglia-mediated neuroinflammation in MPTP-induced Parkinson's disease mouse model.
Liu WW; Wei SZ; Huang GD; Liu LB; Gu C; Shen Y; Wang XH; Xia ST; Xie AM; Hu LF; Wang F; Liu CF
FASEB J; 2020 May; 34(5):6570-6581. PubMed ID: 32246801
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
