305 related articles for article (PubMed ID: 31127417)
1. Understanding the Role of Preferential Exclusion of Sugars and Polyols from Native State IgG1 Monoclonal Antibodies and its Effect on Aggregation and Reversible Self-Association.
Sudrik CM; Cloutier T; Mody N; Sathish HA; Trout BL
Pharm Res; 2019 May; 36(8):109. PubMed ID: 31127417
[TBL] [Abstract][Full Text] [Related]
2. Molecular Computations of Preferential Interaction Coefficients of IgG1 Monoclonal Antibodies with Sorbitol, Sucrose, and Trehalose and the Impact of These Excipients on Aggregation and Viscosity.
Cloutier T; Sudrik C; Mody N; Sathish HA; Trout BL
Mol Pharm; 2019 Aug; 16(8):3657-3664. PubMed ID: 31276620
[TBL] [Abstract][Full Text] [Related]
3. Preferential interactions of trehalose, L-arginine.HCl and sodium chloride with therapeutically relevant IgG1 monoclonal antibodies.
Sudrik C; Cloutier T; Pham P; Samra HS; Trout BL
MAbs; 2017 Oct; 9(7):1155-1168. PubMed ID: 28758834
[TBL] [Abstract][Full Text] [Related]
4. Effect of polyol sugars on the stabilization of monoclonal antibodies.
Nicoud L; Cohrs N; Arosio P; Norrant E; Morbidelli M
Biophys Chem; 2015 Feb; 197():40-6. PubMed ID: 25645712
[TBL] [Abstract][Full Text] [Related]
5. Characterization of antibody-polyol interactions by static light scattering: implications for physical stability of protein formulations.
Abbas SA; Sharma VK; Patapoff TW; Kalonia DS
Int J Pharm; 2013 May; 448(2):382-9. PubMed ID: 23583711
[TBL] [Abstract][Full Text] [Related]
6. Excipients differentially influence the conformational stability and pretransition dynamics of two IgG1 monoclonal antibodies.
Thakkar SV; Joshi SB; Jones ME; Sathish HA; Bishop SM; Volkin DB; Middaugh CR
J Pharm Sci; 2012 Sep; 101(9):3062-77. PubMed ID: 22581714
[TBL] [Abstract][Full Text] [Related]
7. Osmolyte Effects on Monoclonal Antibody Stability and Concentration-Dependent Protein Interactions with Water and Common Osmolytes.
Barnett GV; Razinkov VI; Kerwin BA; Blake S; Qi W; Curtis RA; Roberts CJ
J Phys Chem B; 2016 Apr; 120(13):3318-30. PubMed ID: 27007711
[TBL] [Abstract][Full Text] [Related]
8. Studying Excipient Modulated Physical Stability and Viscosity of Monoclonal Antibody Formulations Using Small-Angle Scattering.
Xu AY; Castellanos MM; Mattison K; Krueger S; Curtis JE
Mol Pharm; 2019 Oct; 16(10):4319-4338. PubMed ID: 31487466
[TBL] [Abstract][Full Text] [Related]
9. A specific molar ratio of stabilizer to protein is required for storage stability of a lyophilized monoclonal antibody.
Cleland JL; Lam X; Kendrick B; Yang J; Yang TH; Overcashier D; Brooks D; Hsu C; Carpenter JF
J Pharm Sci; 2001 Mar; 90(3):310-21. PubMed ID: 11170024
[TBL] [Abstract][Full Text] [Related]
10. Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass spectrometry.
Manikwar P; Majumdar R; Hickey JM; Thakkar SV; Samra HS; Sathish HA; Bishop SM; Middaugh CR; Weis DD; Volkin DB
J Pharm Sci; 2013 Jul; 102(7):2136-51. PubMed ID: 23620222
[TBL] [Abstract][Full Text] [Related]
11. Computational Characterization of Antibody-Excipient Interactions for Rational Excipient Selection Using the Site Identification by Ligand Competitive Saturation-Biologics Approach.
Jo S; Xu A; Curtis JE; Somani S; MacKerell AD
Mol Pharm; 2020 Nov; 17(11):4323-4333. PubMed ID: 32965126
[TBL] [Abstract][Full Text] [Related]
12. Mechanism of protein stabilization by sugars during freeze-drying and storage: native structure preservation, specific interaction, and/or immobilization in a glassy matrix?
Chang L; Shepherd D; Sun J; Ouellette D; Grant KL; Tang XC; Pikal MJ
J Pharm Sci; 2005 Jul; 94(7):1427-44. PubMed ID: 15920775
[TBL] [Abstract][Full Text] [Related]
13. Application of disaccharides alone and in combination, for the improvement of stability and particle properties of spray-freeze dried IgG.
Daneshmand B; Faghihi H; Amini Pouya M; Aghababaie S; Darabi M; Vatanara A
Pharm Dev Technol; 2019 Apr; 24(4):439-447. PubMed ID: 30070161
[TBL] [Abstract][Full Text] [Related]
14. Bilateral Effects of Excipients on Protein Stability: Preferential Interaction Type of Excipient and Surface Aromatic Hydrophobicity of Protein.
Wen L; Zheng X; Wang X; Lan H; Yin Z
Pharm Res; 2017 Jul; 34(7):1378-1390. PubMed ID: 28401430
[TBL] [Abstract][Full Text] [Related]
15. Effect of Arginine on the Aggregation of Protein in Freeze-Dried Formulations Containing Sugars and Polyol: 1-Formulation Development.
Hackl E; Darkwah J; Smith G; Ermolina I
AAPS PharmSciTech; 2018 Feb; 19(2):896-911. PubMed ID: 29047017
[TBL] [Abstract][Full Text] [Related]
16. Molecular computations of preferential interactions of proline, arginine.HCl, and NaCl with IgG1 antibodies and their impact on aggregation and viscosity.
Cloutier TK; Sudrik C; Mody N; Hasige SA; Trout BL
MAbs; 2020; 12(1):1816312. PubMed ID: 32938318
[TBL] [Abstract][Full Text] [Related]
17. Sorbitol crystallization-induced aggregation in frozen mAb formulations.
Piedmonte DM; Hair A; Baker P; Brych L; Nagapudi K; Lin H; Cao W; Hershenson S; Ratnaswamy G
J Pharm Sci; 2015 Feb; 104(2):686-97. PubMed ID: 25219372
[TBL] [Abstract][Full Text] [Related]
18. Characterization of Excipient Effects on Reversible Self-Association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 1.
Hu Y; Arora J; Joshi SB; Esfandiary R; Middaugh CR; Weis DD; Volkin DB
J Pharm Sci; 2020 Jan; 109(1):340-352. PubMed ID: 31201906
[TBL] [Abstract][Full Text] [Related]
19. Characterization of Excipient Effects on Reversible Self-Association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 2.
Hu Y; Toth RT; Joshi SB; Esfandiary R; Middaugh CR; Volkin DB; Weis DD
J Pharm Sci; 2020 Jan; 109(1):353-363. PubMed ID: 31195015
[TBL] [Abstract][Full Text] [Related]
20. Stabilization of IgG1 in spray-dried powders for inhalation.
Schüle S; Schulz-Fademrecht T; Garidel P; Bechtold-Peters K; Frieb W
Eur J Pharm Biopharm; 2008 Aug; 69(3):793-807. PubMed ID: 18477504
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
