105 related articles for article (PubMed ID: 3112774)
1. Analysis of the role of cysteine residues in isopenicillin N synthetase activity by site-directed mutagenesis.
Samson SM; Chapman JL; Belagaje R; Queener SW; Ingolia TD
Proc Natl Acad Sci U S A; 1987 Aug; 84(16):5705-9. PubMed ID: 3112774
[TBL] [Abstract][Full Text] [Related]
2. The functional role of cysteines in isopenicillin N synthase. Correlation of cysteine reactivities toward sulfhydryl reagents with kinetic properties of cysteine mutants.
Kriauciunas A; Frolik CA; Hassell TC; Skatrud PL; Johnson MG; Holbrook NL; Chen VJ
J Biol Chem; 1991 Jun; 266(18):11779-88. PubMed ID: 2050677
[TBL] [Abstract][Full Text] [Related]
3. Thiolate ligation of the active site Fe2+ of isopenicillin N synthase derives from substrate rather than endogenous cysteine: spectroscopic studies of site-specific Cys----Ser mutated enzymes.
Orville AM; Chen VJ; Kriauciunas A; Harpel MR; Fox BG; Münck E; Lipscomb JD
Biochemistry; 1992 May; 31(19):4602-12. PubMed ID: 1316153
[TBL] [Abstract][Full Text] [Related]
4. Characterization of a loss-of-function mutation in the isopenicillin N synthetase gene of Acremonium chrysogenum.
Ramsden M; McQuade BA; Saunders K; Turner MK; Harford S
Gene; 1989 Dec; 85(1):267-73. PubMed ID: 2620834
[TBL] [Abstract][Full Text] [Related]
5. Cloning and expression of the isopenicillin N synthetase gene from Penicillium chrysogenum.
Carr LG; Skatrud PL; Scheetz ME; Queener SW; Ingolia TD
Gene; 1986; 48(2-3):257-66. PubMed ID: 3104145
[TBL] [Abstract][Full Text] [Related]
6. Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerus.
Leskiw BK; Aharonowitz Y; Mevarech M; Wolfe S; Vining LC; Westlake DW; Jensen SE
Gene; 1988; 62(2):187-96. PubMed ID: 3130293
[TBL] [Abstract][Full Text] [Related]
7. Functional analysis of conserved histidine residues in Cephalosporium acremonium isopenicillin N synthase by site-directed mutagenesis.
Tan DS; Sim TS
J Biol Chem; 1996 Jan; 271(2):889-94. PubMed ID: 8557701
[TBL] [Abstract][Full Text] [Related]
8. Purification of isopenicillin N synthetase.
Pang CP; Chakravarti B; Adlington RM; Ting HH; White RL; Jayatilake GS; Baldwin JE; Abraham EP
Biochem J; 1984 Sep; 222(3):789-95. PubMed ID: 6435606
[TBL] [Abstract][Full Text] [Related]
9. Mutational evidence for the role of serine-283 in Cephalosporium acremonium isopenicillin N synthase.
Loke P; Sim TS
FEMS Microbiol Lett; 1998 Aug; 165(2):353-6. PubMed ID: 9841222
[TBL] [Abstract][Full Text] [Related]
10. Analysis of glutamines in catalysis in Cephalosporium acremonium isopenicillin N synthase by site-directed mutagenesis.
Loke P; Sim TS
Biochem Biophys Res Commun; 1998 Nov; 252(2):472-5. PubMed ID: 9826554
[TBL] [Abstract][Full Text] [Related]
11. Replacement of tyrosine-197 and the corresponding tyrosine-195 to isoleucine in Cephalosporium acremonium and Streptomyces clavuligerus isopenicillin N synthase.
Loke P; Sim TS
Z Naturforsch C J Biosci; 2001; 56(9-10):806-9. PubMed ID: 11724386
[TBL] [Abstract][Full Text] [Related]
12. Mutational analysis of conserved glycines 42 and 256 in Cephalosporium acremonium isopenicillin N synthase.
Loke P; Sim TS
Can J Microbiol; 2001 Oct; 47(10):961-4. PubMed ID: 11718551
[TBL] [Abstract][Full Text] [Related]
13. Site-directed mutagenesis of arginine-89 supports the role of its guanidino side-chain in substrate binding by Cephalosporium acremonium isopenicillin N synthase.
Loke P; Sim T
FEMS Microbiol Lett; 1999 Oct; 179(2):423-9. PubMed ID: 10518746
[TBL] [Abstract][Full Text] [Related]
14. Site-directed mutagenesis of proline-285 to leucine in Cephalosporium acremonium isopenicillin-N-synthase affects catalysis and increases soluble expression at higher temperatures.
Loke P; Sim TS
Z Naturforsch C J Biosci; 2001; 56(5-6):413-5. PubMed ID: 11421458
[TBL] [Abstract][Full Text] [Related]
15. Sequences of isopenicillin N synthetase genes suggest horizontal gene transfer from prokaryotes to eukaryotes.
Peñalva MA; Moya A; Dopazo J; Ramón D
Proc Biol Sci; 1990 Sep; 241(1302):164-9. PubMed ID: 1979440
[TBL] [Abstract][Full Text] [Related]
16. N-terminal amino acid sequence and some properties of isopenicillin-N synthetase from Cephalosporium acremonium.
Baldwin JE; Gagnon J; Ting H
FEBS Lett; 1985 Sep; 188(2):253-6. PubMed ID: 3839755
[TBL] [Abstract][Full Text] [Related]
17. Cloning, sequence analysis and transcriptional study of the isopenicillin N synthase of Penicillium chrysogenum AS-P-78.
Barredo JL; Cantoral JM; Alvarez E; Díez B; Martín JF
Mol Gen Genet; 1989 Mar; 216(1):91-8. PubMed ID: 2499766
[TBL] [Abstract][Full Text] [Related]
18. Cloning and expression in Escherichia coli of isopenicillin N synthetase genes from Streptomyces lipmanii and Aspergillus nidulans.
Weigel BJ; Burgett SG; Chen VJ; Skatrud PL; Frolik CA; Queener SW; Ingolia TD
J Bacteriol; 1988 Sep; 170(9):3817-26. PubMed ID: 3045077
[TBL] [Abstract][Full Text] [Related]
19. Mutational analysis of tyrosine-191 in the catalysis of Cephalosporium acremonium isopenicillin N synthase.
Loke P; Sim TS
J Biochem; 2000 Apr; 127(4):585-9. PubMed ID: 10739949
[TBL] [Abstract][Full Text] [Related]
20. Oxygen utilisation by isopenicillin N synthase from Penicillium chrysogenum.
Bainbridge ZA; Scott RI; Perry D
J Chem Technol Biotechnol; 1992; 55(3):233-8. PubMed ID: 1369045
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
