BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

324 related articles for article (PubMed ID: 31134006)

  • 1. Alpha-Herpesvirus Thymidine Kinase Genes Mediate Viral Virulence and Are Potential Therapeutic Targets.
    Xie Y; Wu L; Wang M; Cheng A; Yang Q; Wu Y; Jia R; Zhu D; Zhao X; Chen S; Liu M; Zhang S; Wang Y; Xu Z; Chen Z; Zhu L; Luo Q; Liu Y; Yu Y; Zhang L; Chen X
    Front Microbiol; 2019; 10():941. PubMed ID: 31134006
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Thymidine Kinase-Negative Herpes Simplex Virus 1 Can Efficiently Establish Persistent Infection in Neural Tissues of Nude Mice.
    Huang CY; Yao HW; Wang LC; Shen FH; Hsu SM; Chen SH
    J Virol; 2017 Feb; 91(4):. PubMed ID: 27974554
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective abolishment of pyrimidine nucleoside kinase activity of herpes simplex virus type 1 thymidine kinase by mutation of alanine-167 to tyrosine.
    Degrève B; Esnouf R; De Clercq E; Balzarini J
    Mol Pharmacol; 2000 Dec; 58(6):1326-32. PubMed ID: 11093770
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo.
    Jacobs A; Tjuvajev JG; Dubrovin M; Akhurst T; Balatoni J; Beattie B; Joshi R; Finn R; Larson SM; Herrlinger U; Pechan PA; Chiocca EA; Breakefield XO; Blasberg RG
    Cancer Res; 2001 Apr; 61(7):2983-95. PubMed ID: 11306477
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinetic studies with N2-phenylguanines and with L-thymidine indicate that herpes simplex virus type-1 thymidine kinase and thymidylate kinase share a common active site.
    Maga G; Focher F; Wright GE; Capobianco M; Garbesi A; Bendiscioli A; Spadari S
    Biochem J; 1994 Aug; 302 ( Pt 1)(Pt 1):279-82. PubMed ID: 8068016
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Improved safety of a replication-competent poxvirus-based HIV vaccine with the introduction of the HSV-TK/GCV suicide gene system.
    Zhang Q; Liu Z; Hou J; Wang S; Liu C; Wei M; Liu Y; Shao Y
    Vaccine; 2016 Jun; 34(30):3447-53. PubMed ID: 27195760
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Improved herpes simplex virus type 1 amplicon vectors for proportional coexpression of positron emission tomography marker and therapeutic genes.
    Jacobs AH; Winkeler A; Hartung M; Slack M; Dittmar C; Kummer C; Knoess C; Galldiks N; Vollmar S; Wienhard K; Heiss WD
    Hum Gene Ther; 2003 Feb; 14(3):277-97. PubMed ID: 12639307
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of the E1B 55 kDa gene product in oncolytic adenoviral vectors expressing herpes simplex virus-tk: assessment of antitumor efficacy and toxicity.
    Wildner O; Morris JC
    Cancer Res; 2000 Aug; 60(15):4167-74. PubMed ID: 10945625
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Herpesvirus saimiri pathogenicity enhanced by thymidine kinase of herpes simplex virus.
    Hiller C; Tamgüney G; Stolte N; Mätz-Rensing K; Lorenzen D; Hör S; Thurau M; Wittmann S; Slavin S; Fickenscher H
    Virology; 2000 Dec; 278(2):445-55. PubMed ID: 11118367
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase.
    Degrève B; Esnouf R; De Clercq E; Balzarini J
    Mol Pharmacol; 2001 Feb; 59(2):285-93. PubMed ID: 11160865
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced tumor cell killing in the presence of ganciclovir by herpes simplex virus type 1 vector-directed coexpression of human tumor necrosis factor-alpha and herpes simplex virus thymidine kinase.
    Moriuchi S; Oligino T; Krisky D; Marconi P; Fink D; Cohen J; Glorioso JC
    Cancer Res; 1998 Dec; 58(24):5731-7. PubMed ID: 9865731
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reactivation of thymidine kinase-defective herpes simplex virus is enhanced by nucleoside.
    Tenser RB; Gaydos A; Hay KA
    J Virol; 1996 Feb; 70(2):1271-6. PubMed ID: 8551594
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Utility of ultra-deep sequencing for detection of varicella-zoster virus antiviral resistance mutations.
    Mercier-Darty M; Boutolleau D; Lepeule R; Rodriguez C; Burrel S
    Antiviral Res; 2018 Mar; 151():20-23. PubMed ID: 29337163
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Adenovirus-mediated gene transfer of enhanced Herpes simplex virus thymidine kinase mutants improves prodrug-mediated tumor cell killing.
    Wiewrodt R; Amin K; Kiefer M; Jovanovic VP; Kapoor V; Force S; Chang M; Lanuti M; Black ME; Kaiser LR; Albelda SM
    Cancer Gene Ther; 2003 May; 10(5):353-64. PubMed ID: 12719705
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substrate specificity of feline and canine herpesvirus thymidine kinase.
    Solaroli N; Johansson M; Persoons L; Balzarini J; Karlsson A
    Antiviral Res; 2008 Aug; 79(2):128-32. PubMed ID: 18455811
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The A167Y mutation converts the herpes simplex virus type 1 thymidine kinase into a guanosine analogue kinase.
    Balzarini J; Liekens S; Esnouf R; De Clercq E
    Biochemistry; 2002 May; 41(20):6517-24. PubMed ID: 12009916
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rapid size dependent deletion of foreign gene sequences inserted into attenuated HIV-1 upon infection in vivo: implications for vaccine development.
    Brooks DG; Cohen MD; Jamieson BD; Poon B; Kitchen SG; Chow SA; Chen IS; Zack JA; Koka PS
    Curr HIV Res; 2005 Oct; 3(4):377-92. PubMed ID: 16250884
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Establishment and use of a cell line expressing HSV-1 thymidine kinase to characterize viral thymidine kinase-dependent drug-resistance.
    Kim JH; Park JB; Bae PK; Kim HS; Kim DW; Ahn JK; Lee CK
    Antiviral Res; 2002 Jun; 54(3):163-74. PubMed ID: 12062389
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Epstein-Barr virus thymidine kinase does not phosphorylate ganciclovir or acyclovir and demonstrates a narrow substrate specificity compared to the herpes simplex virus type 1 thymidine kinase.
    Gustafson EA; Chillemi AC; Sage DR; Fingeroth JD
    Antimicrob Agents Chemother; 1998 Nov; 42(11):2923-31. PubMed ID: 9797227
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytotoxicity and cellular uptake of pyrimidine nucleosides for imaging herpes simplex type-1 thymidine kinase (HSV-1 TK) expression in mammalian cells.
    Morin KW; Duan W; Xu L; Zhou A; Moharram S; Knaus EE; McEwan AJ; Wiebe LI
    Nucl Med Biol; 2004 Jul; 31(5):623-30. PubMed ID: 15219281
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.