BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 31137743)

  • 1. POLQ Overexpression Is Associated with an Increased Somatic Mutation Load and PLK4 Overexpression in Lung Adenocarcinoma.
    Shinmura K; Kato H; Kawanishi Y; Yoshimura K; Tsuchiya K; Takahara Y; Hosokawa S; Kawase A; Funai K; Sugimura H
    Cancers (Basel); 2019 May; 11(5):. PubMed ID: 31137743
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Knockdown of POLQ interferes the development and progression of hepatocellular carcinoma through regulating cell proliferation, apoptosis and migration.
    Pan Q; Wang L; Liu Y; Li M; Zhang Y; Peng W; Deng T; Peng ML; Jiang JQ; Tang J; Wang J; Duan HX; Fan SS
    Cancer Cell Int; 2021 Sep; 21(1):482. PubMed ID: 34517891
    [TBL] [Abstract][Full Text] [Related]  

  • 3. WDR62 overexpression is associated with a poor prognosis in patients with lung adenocarcinoma.
    Shinmura K; Kato H; Kawanishi Y; Igarashi H; Inoue Y; Yoshimura K; Nakamura S; Fujita H; Funai K; Tanahashi M; Niwa H; Ogawa H; Sugimura H
    Mol Carcinog; 2017 Aug; 56(8):1984-1991. PubMed ID: 28277612
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Defining the mutation signatures of DNA polymerase θ in cancer genomes.
    Hwang T; Reh S; Dunbayev Y; Zhong Y; Takata Y; Shen J; McBride KM; Murnane JP; Bhak J; Lee S; Wood RD; Takata KI
    NAR Cancer; 2020 Sep; 2(3):zcaa017. PubMed ID: 32885167
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct roles of RAD52 and POLQ in chromosomal break repair and replication stress response.
    Kelso AA; Lopezcolorado FW; Bhargava R; Stark JM
    PLoS Genet; 2019 Aug; 15(8):e1008319. PubMed ID: 31381562
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Co-inhibition of pol θ and HR genes efficiently synergize with cisplatin to suppress cisplatin-resistant lung cancer cells survival.
    Dai CH; Chen P; Li J; Lan T; Chen YC; Qian H; Chen K; Li MY
    Oncotarget; 2016 Oct; 7(40):65157-65170. PubMed ID: 27533083
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Absence of DNA polymerase theta results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes.
    Masuda K; Ouchida R; Hikida M; Nakayama M; Ohara O; Kurosaki T; O-Wang J
    DNA Repair (Amst); 2006 Nov; 5(11):1384-91. PubMed ID: 16890500
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PLK4 overexpression and its effect on centrosome regulation and chromosome stability in human gastric cancer.
    Shinmura K; Kurabe N; Goto M; Yamada H; Natsume H; Konno H; Sugimura H
    Mol Biol Rep; 2014 Oct; 41(10):6635-44. PubMed ID: 24981932
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development.
    Thyme SB; Schier AF
    Cell Rep; 2016 Apr; 15(4):707-714. PubMed ID: 27149851
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Excess Polθ functions in response to replicative stress in homologous recombination-proficient cancer cells.
    Goullet de Rugy T; Bashkurov M; Datti A; Betous R; Guitton-Sert L; Cazaux C; Durocher D; Hoffmann JS
    Biol Open; 2016 Oct; 5(10):1485-1492. PubMed ID: 27612511
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage.
    Yoshimura M; Kohzaki M; Nakamura J; Asagoshi K; Sonoda E; Hou E; Prasad R; Wilson SH; Tano K; Yasui A; Lan L; Seki M; Wood RD; Arakawa H; Buerstedde JM; Hochegger H; Okada T; Hiraoka M; Takeda S
    Mol Cell; 2006 Oct; 24(1):115-25. PubMed ID: 17018297
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reduced expression of the DNA glycosylase gene MUTYH is associated with an increased number of somatic mutations via a reduction in the DNA repair capacity in prostate adenocarcinoma.
    Shinmura K; Kato H; Kawanishi Y; Yoshimura K; Igarashi H; Goto M; Tao H; Inoue Y; Sugiyama T; Furuse H; Ozono S; Sugimura H
    Mol Carcinog; 2017 Feb; 56(2):781-788. PubMed ID: 27253753
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of two POLQ mutants reveals that a polymerase-inactive POLQ retains significant function in tolerance to etoposide and γ-irradiation in mouse B cells.
    Li Y; Gao X; Wang JY
    Genes Cells; 2011 Sep; 16(9):973-83. PubMed ID: 21883722
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Depletion of DNA Polymerase Theta Inhibits Tumor Growth and Promotes Genome Instability through the cGAS-STING-ISG Pathway in Esophageal Squamous Cell Carcinoma.
    Li J; Ko JM; Dai W; Yu VZ; Ng HY; Hoffmann JS; Lung ML
    Cancers (Basel); 2021 Jun; 13(13):. PubMed ID: 34206946
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
    Higgins GS; Harris AL; Prevo R; Helleday T; McKenna WG; Buffa FM
    Oncotarget; 2010 Jul; 1(3):175-84. PubMed ID: 20700469
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analyses of expressions and prognostic values of Polo-like kinases in non-small cell lung cancer.
    Zeng Y; Li N; Liu W; Zeng M; Cheng J; Huang J
    J Cancer Res Clin Oncol; 2020 Oct; 146(10):2447-2460. PubMed ID: 32627077
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A DNA repair variant in POLQ (c.-1060A > G) is associated to hereditary breast cancer patients: a case-control study.
    Brandalize AP; Schüler-Faccini L; Hoffmann JS; Caleffi M; Cazaux C; Ashton-Prolla P
    BMC Cancer; 2014 Nov; 14():850. PubMed ID: 25409685
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm.
    Shima N; Munroe RJ; Schimenti JC
    Mol Cell Biol; 2004 Dec; 24(23):10381-9. PubMed ID: 15542845
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aberrant expression and mutation-inducing activity of AID in human lung cancer.
    Shinmura K; Igarashi H; Goto M; Tao H; Yamada H; Matsuura S; Tajima M; Matsuda T; Yamane A; Funai K; Tanahashi M; Niwa H; Ogawa H; Sugimura H
    Ann Surg Oncol; 2011 Jul; 18(7):2084-92. PubMed ID: 21290192
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The SCF/Slimb ubiquitin ligase limits centrosome amplification through degradation of SAK/PLK4.
    Cunha-Ferreira I; Rodrigues-Martins A; Bento I; Riparbelli M; Zhang W; Laue E; Callaini G; Glover DM; Bettencourt-Dias M
    Curr Biol; 2009 Jan; 19(1):43-9. PubMed ID: 19084407
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.