These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
557 related articles for article (PubMed ID: 31137846)
1. Inhibition of Hedgehog Signaling in Fibroblasts, Pancreatic, and Lung Tumor Cells by Oxy186, an Oxysterol Analogue with Drug-Like Properties. Wang F; Stappenbeck F; Parhami F Cells; 2019 May; 8(5):. PubMed ID: 31137846 [TBL] [Abstract][Full Text] [Related]
2. Inhibition of Pancreatic Cancer Cell-Induced Paracrine Hedgehog Signaling by Liver X Receptor Agonists and Oxy16, a Naturally Occurring Oxysterol. Wang F; Stappenbeck F; Matsui W; Parhami F J Cell Biochem; 2017 Mar; 118(3):499-509. PubMed ID: 27490478 [TBL] [Abstract][Full Text] [Related]
3. DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance. Gruber W; Hutzinger M; Elmer DP; Parigger T; Sternberg C; Cegielkowski L; Zaja M; Leban J; Michel S; Hamm S; Vitt D; Aberger F Oncotarget; 2016 Feb; 7(6):7134-48. PubMed ID: 26784250 [TBL] [Abstract][Full Text] [Related]
4. In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors. Benvenuto M; Masuelli L; De Smaele E; Fantini M; Mattera R; Cucchi D; Bonanno E; Di Stefano E; Frajese GV; Orlandi A; Screpanti I; Gulino A; Modesti A; Bei R Oncotarget; 2016 Feb; 7(8):9250-70. PubMed ID: 26843616 [TBL] [Abstract][Full Text] [Related]
5. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro. You M; Varona-Santos J; Singh S; Robbins DJ; Savaraj N; Nguyen DM J Thorac Cardiovasc Surg; 2014 Jan; 147(1):508-16. PubMed ID: 24094913 [TBL] [Abstract][Full Text] [Related]
6. Adenovirus vector-mediated Gli1 siRNA induces growth inhibition and apoptosis in human pancreatic cancer with Smo-dependent or Smo-independent Hh pathway activation in vitro and in vivo. Guo J; Gao J; Li Z; Gong Y; Man X; Jin J; Wu H Cancer Lett; 2013 Oct; 339(2):185-94. PubMed ID: 23791879 [TBL] [Abstract][Full Text] [Related]
7. Novel-smoothened inhibitors for therapeutic targeting of naïve and drug-resistant hedgehog pathway-driven cancers. Li QR; Zhao H; Zhang XS; Lang H; Yu K Acta Pharmacol Sin; 2019 Feb; 40(2):257-267. PubMed ID: 29777201 [TBL] [Abstract][Full Text] [Related]
8. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury. Grzelak CA; Martelotto LG; Sigglekow ND; Patkunanathan B; Ajami K; Calabro SR; Dwyer BJ; Tirnitz-Parker JE; Watkins DN; Warner FJ; Shackel NA; McCaughan GW J Hepatol; 2014 Jan; 60(1):143-51. PubMed ID: 23978713 [TBL] [Abstract][Full Text] [Related]
9. Targeting class I histone deacetylases by the novel small molecule inhibitor 4SC-202 blocks oncogenic hedgehog-GLI signaling and overcomes smoothened inhibitor resistance. Gruber W; Peer E; Elmer DP; Sternberg C; Tesanovic S; Del Burgo P; Coni S; Canettieri G; Neureiter D; Bartz R; Kohlhof H; Vitt D; Aberger F Int J Cancer; 2018 Mar; 142(5):968-975. PubMed ID: 29055107 [TBL] [Abstract][Full Text] [Related]
10. Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma. Pietrobono S; Gaudio E; Gagliardi S; Zitani M; Carrassa L; Migliorini F; Petricci E; Manetti F; Makukhin N; Bond AG; Paradise BD; Ciulli A; Fernandez-Zapico ME; Bertoni F; Stecca B Oncogene; 2021 Jun; 40(22):3799-3814. PubMed ID: 33958721 [TBL] [Abstract][Full Text] [Related]
11. CDK7 inhibition suppresses aberrant hedgehog pathway and overcomes resistance to smoothened antagonists. Liu F; Jiang W; Sui Y; Meng W; Hou L; Li T; Li M; Zhang L; Mo J; Wang J; Zhao Y; Zhang L; Ma J; Tang Y Proc Natl Acad Sci U S A; 2019 Jun; 116(26):12986-12995. PubMed ID: 31182587 [TBL] [Abstract][Full Text] [Related]
12. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers. Long J; Li B; Rodriguez-Blanco J; Pastori C; Volmar CH; Wahlestedt C; Capobianco A; Bai F; Pei XH; Ayad NG; Robbins DJ J Biol Chem; 2014 Dec; 289(51):35494-502. PubMed ID: 25355313 [TBL] [Abstract][Full Text] [Related]
13. CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway. Chen J; Lv H; Hu J; Ji M; Xue N; Li C; Ma S; Zhou Q; Lin B; Li Y; Yu S; Chen X Cancer Lett; 2016 Oct; 381(2):391-403. PubMed ID: 27495899 [TBL] [Abstract][Full Text] [Related]
14. Targeting the Hedgehog pathway with novel Gli1 hydrophobic tagging degraders. Li X; Sun R; Wu H; Zheng C; Long YQ Bioorg Chem; 2023 Sep; 138():106649. PubMed ID: 37307715 [TBL] [Abstract][Full Text] [Related]
15. Hedgehog Signaling and Truncated GLI1 in Cancer. Doheny D; Manore SG; Wong GL; Lo HW Cells; 2020 Sep; 9(9):. PubMed ID: 32957513 [TBL] [Abstract][Full Text] [Related]
16. Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway. Beauchamp EM; Ringer L; Bulut G; Sajwan KP; Hall MD; Lee YC; Peaceman D; Ozdemirli M; Rodriguez O; Macdonald TJ; Albanese C; Toretsky JA; Uren A J Clin Invest; 2011 Jan; 121(1):148-60. PubMed ID: 21183792 [TBL] [Abstract][Full Text] [Related]
17. Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer. Onishi H; Kai M; Odate S; Iwasaki H; Morifuji Y; Ogino T; Morisaki T; Nakashima Y; Katano M Cancer Sci; 2011 Jun; 102(6):1144-50. PubMed ID: 21338440 [TBL] [Abstract][Full Text] [Related]
18. Pyrvinium attenuates Hedgehog signaling downstream of smoothened. Li B; Fei DL; Flaveny CA; Dahmane N; Baubet V; Wang Z; Bai F; Pei XH; Rodriguez-Blanco J; Hang B; Orton D; Han L; Wang B; Capobianco AJ; Lee E; Robbins DJ Cancer Res; 2014 Sep; 74(17):4811-21. PubMed ID: 24994715 [TBL] [Abstract][Full Text] [Related]
19. Overexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancer-associated fibroblasts. Walter K; Omura N; Hong SM; Griffith M; Vincent A; Borges M; Goggins M Clin Cancer Res; 2010 Mar; 16(6):1781-9. PubMed ID: 20215540 [TBL] [Abstract][Full Text] [Related]
20. Resveratrol Activated Sonic Hedgehog Signaling to Enhance Viability of NIH3T3 Cells in Vitro via Regulation of Sirt1. Guo S; Liao H; Liu J; Liu J; Tang F; He Z; Li Y; Yang Q Cell Physiol Biochem; 2018; 50(4):1346-1360. PubMed ID: 30355933 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]