245 related articles for article (PubMed ID: 31138104)
21. Prospective validation of a comprehensive in silico hERG model and its applications to commercial compound and drug databases.
Doddareddy MR; Klaasse EC; Shagufta ; Ijzerman AP; Bender A
ChemMedChem; 2010 May; 5(5):716-29. PubMed ID: 20349498
[TBL] [Abstract][Full Text] [Related]
22. Combined receptor and ligand-based approach to the universal pharmacophore model development for studies of drug blockade to the hERG1 pore domain.
Durdagi S; Duff HJ; Noskov SY
J Chem Inf Model; 2011 Feb; 51(2):463-74. PubMed ID: 21241063
[TBL] [Abstract][Full Text] [Related]
23. hERG channel trafficking: novel targets in drug-induced long QT syndrome.
Dennis A; Wang L; Wan X; Ficker E
Biochem Soc Trans; 2007 Nov; 35(Pt 5):1060-3. PubMed ID: 17956279
[TBL] [Abstract][Full Text] [Related]
24. Molecular dynamics of hERG channel: insights into understanding the binding of small molecules for detuning cardiotoxicity.
Koulgi S; Jani V; Nair V; Saini JS; Phukan S; Sonavane U; Joshi R; Kamboj R; Palle V
J Biomol Struct Dyn; 2022 Aug; 40(13):5996-6012. PubMed ID: 33494645
[TBL] [Abstract][Full Text] [Related]
25. BayeshERG: a robust, reliable and interpretable deep learning model for predicting hERG channel blockers.
Kim H; Park M; Lee I; Nam H
Brief Bioinform; 2022 Jul; 23(4):. PubMed ID: 35709752
[TBL] [Abstract][Full Text] [Related]
26. In silico prediction of the chemical block of human ether-a-go-go-related gene (hERG) K+ current.
Inanobe A; Kamiya N; Murakami S; Fukunishi Y; Nakamura H; Kurachi Y
J Physiol Sci; 2008 Dec; 58(7):459-70. PubMed ID: 19032804
[TBL] [Abstract][Full Text] [Related]
27. ADMET evaluation in drug discovery. 12. Development of binary classification models for prediction of hERG potassium channel blockage.
Wang S; Li Y; Wang J; Chen L; Zhang L; Yu H; Hou T
Mol Pharm; 2012 Apr; 9(4):996-1010. PubMed ID: 22380484
[TBL] [Abstract][Full Text] [Related]
28. Development of Safe Drugs: The hERG Challenge.
Kalyaanamoorthy S; Barakat KH
Med Res Rev; 2018 Mar; 38(2):525-555. PubMed ID: 28467598
[TBL] [Abstract][Full Text] [Related]
29. hERG agonists pose challenges to web-based machine learning methods for prediction of drug-hERG channel interaction.
El Harchi A; Hancox JC
J Pharmacol Toxicol Methods; 2023; 123():107293. PubMed ID: 37468081
[TBL] [Abstract][Full Text] [Related]
30. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
Davie C; Pierre-Valentin J; Pollard C; Standen N; Mitcheson J; Alexander P; Thong B
J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182
[TBL] [Abstract][Full Text] [Related]
31. In silico prediction of hERG blockers using machine learning and deep learning approaches.
Chen Y; Yu X; Li W; Tang Y; Liu G
J Appl Toxicol; 2023 Oct; 43(10):1462-1475. PubMed ID: 37093028
[TBL] [Abstract][Full Text] [Related]
32. [HERG K+ channel, the target of anti-arrhythmias drugs].
Guan FY; Yang SJ
Yao Xue Xue Bao; 2007 Jul; 42(7):687-91. PubMed ID: 17882949
[TBL] [Abstract][Full Text] [Related]
33. In silico binary classification QSAR models based on 4D-fingerprints and MOE descriptors for prediction of hERG blockage.
Su BH; Shen MY; Esposito EX; Hopfinger AJ; Tseng YJ
J Chem Inf Model; 2010 Jul; 50(7):1304-18. PubMed ID: 20565102
[TBL] [Abstract][Full Text] [Related]
34. A risk assessment of human ether-a-go-go-related gene potassium channel inhibition by using lipophilicity and basicity for drug discovery.
Kawai Y; Tsukamoto S; Ito J; Akimoto K; Takahashi M
Chem Pharm Bull (Tokyo); 2011; 59(9):1110-6. PubMed ID: 21881254
[TBL] [Abstract][Full Text] [Related]
35. Development and evaluation of an in silico model for hERG binding.
Song M; Clark M
J Chem Inf Model; 2006; 46(1):392-400. PubMed ID: 16426073
[TBL] [Abstract][Full Text] [Related]
36. Cardiac glycosides as novel inhibitors of human ether-a-go-go-related gene channel trafficking.
Wang L; Wible BA; Wan X; Ficker E
J Pharmacol Exp Ther; 2007 Feb; 320(2):525-34. PubMed ID: 17095614
[TBL] [Abstract][Full Text] [Related]
37. Induction of autoimmune response to the extracellular loop of the HERG channel pore induces QTc prolongation in guinea-pigs.
Fabris F; Yue Y; Qu Y; Chahine M; Sobie E; Lee P; Wieczorek R; Jiang XC; Capecchi PL; Laghi-Pasini F; Lazzerini PE; Boutjdir M
J Physiol; 2016 Nov; 594(21):6175-6187. PubMed ID: 27296897
[TBL] [Abstract][Full Text] [Related]
38. Novel Bayesian classification models for predicting compounds blocking hERG potassium channels.
Liu LL; Lu J; Lu Y; Zheng MY; Luo XM; Zhu WL; Jiang HL; Chen KX
Acta Pharmacol Sin; 2014 Aug; 35(8):1093-102. PubMed ID: 24976154
[TBL] [Abstract][Full Text] [Related]
39. Regulation of the human ether-a-go-go-related gene (hERG) potassium channel by Nedd4 family interacting proteins (Ndfips).
Kang Y; Guo J; Yang T; Li W; Zhang S
Biochem J; 2015 Nov; 472(1):71-82. PubMed ID: 26363003
[TBL] [Abstract][Full Text] [Related]
40. A binary QSAR model for classification of hERG potassium channel blockers.
Thai KM; Ecker GF
Bioorg Med Chem; 2008 Apr; 16(7):4107-19. PubMed ID: 18243713
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
