249 related articles for article (PubMed ID: 31142783)
1. Berberine alleviates hyperglycemia by targeting hepatic glucokinase in diabetic db/db mice.
Li M; Dang Y; Li Q; Zhou W; Zuo J; Yao Z; Zhang L; Ji G
Sci Rep; 2019 May; 9(1):8003. PubMed ID: 31142783
[TBL] [Abstract][Full Text] [Related]
2. Recent Updates on Glucokinase Activators and Glucokinase Regulatory Protein Disrupters for the Treatment of Type 2 Diabetes Mellitus.
Kaushik A; Kaushik M
Curr Diabetes Rev; 2019; 15(3):205-212. PubMed ID: 30039763
[TBL] [Abstract][Full Text] [Related]
3. Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors.
Lloyd DJ; St Jean DJ; Kurzeja RJ; Wahl RC; Michelsen K; Cupples R; Chen M; Wu J; Sivits G; Helmering J; Komorowski R; Ashton KS; Pennington LD; Fotsch C; Vazir M; Chen K; Chmait S; Zhang J; Liu L; Norman MH; Andrews KL; Bartberger MD; Van G; Galbreath EJ; Vonderfecht SL; Wang M; Jordan SR; Véniant MM; Hale C
Nature; 2013 Dec; 504(7480):437-40. PubMed ID: 24226772
[TBL] [Abstract][Full Text] [Related]
4. Glucose toxicity is responsible for the development of impaired regulation of endogenous glucose production and hepatic glucokinase in Zucker diabetic fatty rats.
Fujimoto Y; Torres TP; Donahue EP; Shiota M
Diabetes; 2006 Sep; 55(9):2479-90. PubMed ID: 16936196
[TBL] [Abstract][Full Text] [Related]
5. Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation.
Farrelly D; Brown KS; Tieman A; Ren J; Lira SA; Hagan D; Gregg R; Mookhtiar KA; Hariharan N
Proc Natl Acad Sci U S A; 1999 Dec; 96(25):14511-6. PubMed ID: 10588736
[TBL] [Abstract][Full Text] [Related]
6. Acetylation of glucokinase regulatory protein decreases glucose metabolism by suppressing glucokinase activity.
Park JM; Kim TH; Jo SH; Kim MY; Ahn YH
Sci Rep; 2015 Dec; 5():17395. PubMed ID: 26620281
[TBL] [Abstract][Full Text] [Related]
7. Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis.
Xia X; Yan J; Shen Y; Tang K; Yin J; Zhang Y; Yang D; Liang H; Ye J; Weng J
PLoS One; 2011 Feb; 6(2):e16556. PubMed ID: 21304897
[TBL] [Abstract][Full Text] [Related]
8. Glucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity.
Ueta K; O'Brien TP; McCoy GA; Kim K; Healey EC; Farmer TD; Donahue EP; Condren AB; Printz RL; Shiota M
Am J Physiol Endocrinol Metab; 2014 Jun; 306(11):E1225-38. PubMed ID: 24714398
[TBL] [Abstract][Full Text] [Related]
9. Treatment of type 2 diabetes by adenoviral-mediated overexpression of the glucokinase regulatory protein.
Slosberg ED; Desai UJ; Fanelli B; St Denny I; Connelly S; Kaleko M; Boettcher BR; Caplan SL
Diabetes; 2001 Aug; 50(8):1813-20. PubMed ID: 11473043
[TBL] [Abstract][Full Text] [Related]
10. An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism.
Futamura M; Hosaka H; Kadotani A; Shimazaki H; Sasaki K; Ohyama S; Nishimura T; Eiki J; Nagata Y
J Biol Chem; 2006 Dec; 281(49):37668-74. PubMed ID: 17028192
[TBL] [Abstract][Full Text] [Related]
11. Glucosamine-induced inhibition of liver glucokinase impairs the ability of hyperglycemia to suppress endogenous glucose production.
Barzilai N; Hawkins M; Angelov I; Hu M; Rossetti L
Diabetes; 1996 Oct; 45(10):1329-35. PubMed ID: 8826967
[TBL] [Abstract][Full Text] [Related]
12. Berberine ameliorates glucocorticoid-induced hyperglycemia: an in vitro and in vivo study.
Gupta M; Rumman M; Singh B; Mahdi AA; Pandey S
Naunyn Schmiedebergs Arch Pharmacol; 2024 Mar; 397(3):1647-1658. PubMed ID: 37704773
[TBL] [Abstract][Full Text] [Related]
13. Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression.
Zhang H; Wei J; Xue R; Wu JD; Zhao W; Wang ZZ; Wang SK; Zhou ZX; Song DQ; Wang YM; Pan HN; Kong WJ; Jiang JD
Metabolism; 2010 Feb; 59(2):285-92. PubMed ID: 19800084
[TBL] [Abstract][Full Text] [Related]
14. Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression.
Kong WJ; Zhang H; Song DQ; Xue R; Zhao W; Wei J; Wang YM; Shan N; Zhou ZX; Yang P; You XF; Li ZR; Si SY; Zhao LX; Pan HN; Jiang JD
Metabolism; 2009 Jan; 58(1):109-19. PubMed ID: 19059538
[TBL] [Abstract][Full Text] [Related]
15. [Effect of berberine on insulin secretion and glucokinase activity of NIT-1 cells].
Wang ZS; Lu FE; Chen G; Xu LJ; Wang KF; Zou X
Yao Xue Xue Bao; 2007 Oct; 42(10):1045-9. PubMed ID: 18229609
[TBL] [Abstract][Full Text] [Related]
16. In silico network pharmacology and in vivo analysis of berberine-related mechanisms against type 2 diabetes mellitus and its complications.
Di S; Han L; An X; Kong R; Gao Z; Yang Y; Wang X; Zhang P; Ding Q; Wu H; Wang H; Zhao L; Tong X
J Ethnopharmacol; 2021 Aug; 276():114180. PubMed ID: 33957209
[TBL] [Abstract][Full Text] [Related]
17. Insulin-receptor substrate-2 (irs-2) is required for maintaining glucokinase and glucokinase regulatory protein expression in mouse liver.
Roncero I; Alvarez E; Acosta C; Sanz C; Barrio P; Hurtado-Carneiro V; Burks D; Blázquez E
PLoS One; 2013; 8(4):e58797. PubMed ID: 23560040
[TBL] [Abstract][Full Text] [Related]
18. Amorphous solid dispersion of Berberine mitigates apoptosis via iPLA
Li J; Du H; Zhang M; Zhang Z; Teng F; Zhao Y; Zhang W; Yu Y; Feng L; Cui X; Zhang M; Lu T; Guan F; Chen L
Int J Biol Sci; 2019; 15(7):1533-1545. PubMed ID: 31337982
[No Abstract] [Full Text] [Related]
19. TMG-123, a novel glucokinase activator, exerts durable effects on hyperglycemia without increasing triglyceride in diabetic animal models.
Tsumura Y; Tsushima Y; Tamura A; Hasebe M; Kanou M; Kato H; Kobayashi T
PLoS One; 2017; 12(2):e0172252. PubMed ID: 28207836
[TBL] [Abstract][Full Text] [Related]
20. Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice.
Xue M; Zhang L; Yang MX; Zhang W; Li XM; Ou ZM; Li ZP; Liu SH; Li XJ; Yang SY
Int J Nanomedicine; 2015; 10():5049-57. PubMed ID: 26346310
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]