426 related articles for article (PubMed ID: 31144442)
1. Mechanism of TRPM2 channel gating revealed by cryo-EM.
Xia S; Wang L; Fu TM; Wu H
FEBS J; 2019 Sep; 286(17):3333-3339. PubMed ID: 31144442
[TBL] [Abstract][Full Text] [Related]
2. Structures and gating mechanism of human TRPM2.
Wang L; Fu TM; Zhou Y; Xia S; Greka A; Wu H
Science; 2018 Dec; 362(6421):. PubMed ID: 30467180
[TBL] [Abstract][Full Text] [Related]
3. Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium.
Huang Y; Winkler PA; Sun W; Lü W; Du J
Nature; 2018 Oct; 562(7725):145-149. PubMed ID: 30250252
[TBL] [Abstract][Full Text] [Related]
4. Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.
Yin Y; Wu M; Hsu AL; Borschel WF; Borgnia MJ; Lander GC; Lee SY
Nat Commun; 2019 Aug; 10(1):3740. PubMed ID: 31431622
[TBL] [Abstract][Full Text] [Related]
5. Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel.
Huang Y; Roth B; Lü W; Du J
Elife; 2019 Sep; 8():. PubMed ID: 31513012
[TBL] [Abstract][Full Text] [Related]
6. Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.
Fliegert R; Watt JM; Schöbel A; Rozewitz MD; Moreau C; Kirchberger T; Thomas MP; Sick W; Araujo AC; Harneit A; Potter BVL; Guse AH
Biochem J; 2017 Jun; 474(13):2159-2175. PubMed ID: 28515263
[TBL] [Abstract][Full Text] [Related]
7. Four Ca2+ ions activate TRPM2 channels by binding in deep crevices near the pore but intracellularly of the gate.
Csanády L; Törocsik B
J Gen Physiol; 2009 Feb; 133(2):189-203. PubMed ID: 19171771
[TBL] [Abstract][Full Text] [Related]
8. TRPM2: a calcium influx pathway regulated by oxidative stress and the novel second messenger ADP-ribose.
Kühn FJ; Heiner I; Lückhoff A
Pflugers Arch; 2005 Oct; 451(1):212-9. PubMed ID: 15952035
[TBL] [Abstract][Full Text] [Related]
9. Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel.
Yu X; Xie Y; Zhang X; Ma C; Liu L; Zhen W; Xu L; Zhang J; Liang Y; Zhao L; Gao X; Yu P; Luo J; Jiang LH; Nie Y; Yang F; Guo J; Yang W
Cell Rep; 2021 Nov; 37(7):110025. PubMed ID: 34788616
[TBL] [Abstract][Full Text] [Related]
10. Intracellular calcium activates TRPM2 and its alternative spliced isoforms.
Du J; Xie J; Yue L
Proc Natl Acad Sci U S A; 2009 Apr; 106(17):7239-44. PubMed ID: 19372375
[TBL] [Abstract][Full Text] [Related]
11. Structure of a TRPM2 channel in complex with Ca
Zhang Z; Tóth B; Szollosi A; Chen J; Csanády L
Elife; 2018 May; 7():. PubMed ID: 29745897
[TBL] [Abstract][Full Text] [Related]
12. The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn
Sander S; Pick J; Gattkowski E; Fliegert R; Tidow H
Protein Sci; 2022 Jun; 31(6):e4320. PubMed ID: 35634784
[TBL] [Abstract][Full Text] [Related]
13. Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels.
Perraud AL; Takanishi CL; Shen B; Kang S; Smith MK; Schmitz C; Knowles HM; Ferraris D; Li W; Zhang J; Stoddard BL; Scharenberg AM
J Biol Chem; 2005 Feb; 280(7):6138-48. PubMed ID: 15561722
[TBL] [Abstract][Full Text] [Related]
14. TRPM2: a multifunctional ion channel for calcium signalling.
Sumoza-Toledo A; Penner R
J Physiol; 2011 Apr; 589(Pt 7):1515-25. PubMed ID: 21135052
[TBL] [Abstract][Full Text] [Related]
15. Selective profiling of N- and C-terminal nucleotide-binding sites in a TRPM2 channel.
Tóth B; Iordanov I; Csanády L
J Gen Physiol; 2020 May; 152(5):. PubMed ID: 32211872
[TBL] [Abstract][Full Text] [Related]
16. Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents.
Tóth B; Csanády L
Proc Natl Acad Sci U S A; 2012 Aug; 109(33):13440-5. PubMed ID: 22847436
[TBL] [Abstract][Full Text] [Related]
17. TRPM2 cation channels, oxidative stress and neurological diseases: where are we now?
Nazıroğlu M
Neurochem Res; 2011 Mar; 36(3):355-66. PubMed ID: 21140288
[TBL] [Abstract][Full Text] [Related]
18. Direct Gating of the TRPM2 Channel by cADPR via Specific Interactions with the ADPR Binding Pocket.
Yu P; Liu Z; Yu X; Ye P; Liu H; Xue X; Yang L; Li Z; Wu Y; Fang C; Zhao YJ; Yang F; Luo JH; Jiang LH; Zhang L; Zhang L; Yang W
Cell Rep; 2019 Jun; 27(12):3684-3695.e4. PubMed ID: 31216484
[TBL] [Abstract][Full Text] [Related]
19. TRPM2.
Faouzi M; Penner R
Handb Exp Pharmacol; 2014; 222():403-26. PubMed ID: 24756715
[TBL] [Abstract][Full Text] [Related]
20. The Role of TRPM2 in Endothelial Function and Dysfunction.
Zielińska W; Zabrzyński J; Gagat M; Grzanka A
Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34299254
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]