These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

300 related articles for article (PubMed ID: 31148170)

  • 1. Leucine-rich repeat kinase 2 phosphorylation on synapsin I regulates glutamate release at pre-synaptic sites.
    Marte A; Russo I; Rebosio C; Valente P; Belluzzi E; Pischedda F; Montani C; Lavarello C; Petretto A; Fedele E; Baldelli P; Benfenati F; Piccoli G; Greggio E; Onofri F
    J Neurochem; 2019 Aug; 150(3):264-281. PubMed ID: 31148170
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The LRRK2 G2385R variant is a partial loss-of-function mutation that affects synaptic vesicle trafficking through altered protein interactions.
    Carrion MDP; Marsicano S; Daniele F; Marte A; Pischedda F; Di Cairano E; Piovesana E; von Zweydorf F; Kremmer E; Gloeckner CJ; Onofri F; Perego C; Piccoli G
    Sci Rep; 2017 Jul; 7(1):5377. PubMed ID: 28710481
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking in Ventral Midbrain Neurons.
    Pan PY; Li X; Wang J; Powell J; Wang Q; Zhang Y; Chen Z; Wicinski B; Hof P; Ryan TA; Yue Z
    J Neurosci; 2017 Nov; 37(47):11366-11376. PubMed ID: 29054882
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Leucine-rich repeat kinase 2 (LRRK2) inhibitors differentially modulate glutamate release and Serine935 LRRK2 phosphorylation in striatal and cerebrocortical synaptosomes.
    Mercatelli D; Bolognesi P; Frassineti M; Pisanò CA; Longo F; Shimshek DR; Morari M
    Pharmacol Res Perspect; 2019 Jun; 7(3):e00484. PubMed ID: 31149340
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dopamine D2 receptor activation potently inhibits striatal glutamatergic transmission in a G2019S LRRK2 genetic model of Parkinson's disease.
    Tozzi A; Durante V; Bastioli G; Mazzocchetti P; Novello S; Mechelli A; Morari M; Costa C; Mancini A; Di Filippo M; Calabresi P
    Neurobiol Dis; 2018 Oct; 118():1-8. PubMed ID: 29908325
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Huntingtin-associated protein-1 is a synapsin I-binding protein regulating synaptic vesicle exocytosis and synapsin I trafficking.
    Mackenzie KD; Lumsden AL; Guo F; Duffield MD; Chataway T; Lim Y; Zhou XF; Keating DJ
    J Neurochem; 2016 Sep; 138(5):710-21. PubMed ID: 27315547
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition.
    Kadgien CA; Kamesh A; Milnerwood AJ
    Mol Brain; 2021 Sep; 14(1):143. PubMed ID: 34530877
    [TBL] [Abstract][Full Text] [Related]  

  • 8. P62/SQSTM1 is a novel leucine-rich repeat kinase 2 (LRRK2) substrate that enhances neuronal toxicity.
    Kalogeropulou AF; Zhao J; Bolliger MF; Memou A; Narasimha S; Molitor TP; Wilson WH; Rideout HJ; Nichols RJ
    Biochem J; 2018 Apr; 475(7):1271-1293. PubMed ID: 29519959
    [TBL] [Abstract][Full Text] [Related]  

  • 9. LRRK2 impairs autophagy by mediating phosphorylation of leucyl-tRNA synthetase.
    Ho DH; Kim H; Nam D; Sim H; Kim J; Kim HG; Son I; Seol W
    Cell Biochem Funct; 2018 Dec; 36(8):431-442. PubMed ID: 30411383
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tyrosine phosphorylation of synapsin I by Src regulates synaptic-vesicle trafficking.
    Messa M; Congia S; Defranchi E; Valtorta F; Fassio A; Onofri F; Benfenati F
    J Cell Sci; 2010 Jul; 123(Pt 13):2256-65. PubMed ID: 20530578
    [TBL] [Abstract][Full Text] [Related]  

  • 11. G2019S LRRK2 enhances the neuronal transmission of tau in the mouse brain.
    Nguyen APT; Daniel G; Valdés P; Islam MS; Schneider BL; Moore DJ
    Hum Mol Genet; 2018 Jan; 27(1):120-134. PubMed ID: 29088368
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson's disease.
    Islam MS; Nolte H; Jacob W; Ziegler AB; Pütz S; Grosjean Y; Szczepanowska K; Trifunovic A; Braun T; Heumann H; Heumann R; Hovemann B; Moore DJ; Krüger M
    Hum Mol Genet; 2016 Dec; 25(24):5365-5382. PubMed ID: 27794539
    [TBL] [Abstract][Full Text] [Related]  

  • 13. LRRK2 at the pre-synaptic site: A 16-years perspective.
    Pischedda F; Piccoli G
    J Neurochem; 2021 Apr; 157(2):297-311. PubMed ID: 33206398
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain.
    Piccoli G; Onofri F; Cirnaru MD; Kaiser CJ; Jagtap P; Kastenmüller A; Pischedda F; Marte A; von Zweydorf F; Vogt A; Giesert F; Pan L; Antonucci F; Kiel C; Zhang M; Weinkauf S; Sattler M; Sala C; Matteoli M; Ueffing M; Gloeckner CJ
    Mol Cell Biol; 2014 Jun; 34(12):2147-61. PubMed ID: 24687852
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Altered Development of Synapse Structure and Function in Striatum Caused by Parkinson's Disease-Linked LRRK2-G2019S Mutation.
    Matikainen-Ankney BA; Kezunovic N; Mesias RE; Tian Y; Williams FM; Huntley GW; Benson DL
    J Neurosci; 2016 Jul; 36(27):7128-41. PubMed ID: 27383589
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Kinetic analysis of the phosphorylation-dependent interactions of synapsin I with rat brain synaptic vesicles.
    Stefani G; Onofri F; Valtorta F; Vaccaro P; Greengard P; Benfenati F
    J Physiol; 1997 Nov; 504 ( Pt 3)(Pt 3):501-15. PubMed ID: 9401959
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synapsin phosphorylation by SRC tyrosine kinase enhances SRC activity in synaptic vesicles.
    Onofri F; Messa M; Matafora V; Bonanno G; Corradi A; Bachi A; Valtorta F; Benfenati F
    J Biol Chem; 2007 May; 282(21):15754-67. PubMed ID: 17400547
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synapsins as mediators of BDNF-enhanced neurotransmitter release.
    Jovanovic JN; Czernik AJ; Fienberg AA; Greengard P; Sihra TS
    Nat Neurosci; 2000 Apr; 3(4):323-9. PubMed ID: 10725920
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphorylation of synapsin I by cyclin-dependent kinase-5 sets the ratio between the resting and recycling pools of synaptic vesicles at hippocampal synapses.
    Verstegen AM; Tagliatti E; Lignani G; Marte A; Stolero T; Atias M; Corradi A; Valtorta F; Gitler D; Onofri F; Fassio A; Benfenati F
    J Neurosci; 2014 May; 34(21):7266-80. PubMed ID: 24849359
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.
    Jovanovic JN; Sihra TS; Nairn AC; Hemmings HC; Greengard P; Czernik AJ
    J Neurosci; 2001 Oct; 21(20):7944-53. PubMed ID: 11588168
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.