BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

278 related articles for article (PubMed ID: 31155062)

  • 1. Computational structural enzymology methodologies for the study and engineering of fatty acid synthases, polyketide synthases and nonribosomal peptide synthetases.
    Schaub AJ; Moreno GO; Zhao S; Truong HV; Luo R; Tsai SC
    Methods Enzymol; 2019; 622():375-409. PubMed ID: 31155062
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The chemical biology of modular biosynthetic enzymes.
    Meier JL; Burkart MD
    Chem Soc Rev; 2009 Jul; 38(7):2012-45. PubMed ID: 19551180
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Structural Enzymology of Iterative Aromatic Polyketide Synthases: A Critical Comparison with Fatty Acid Synthases.
    Tsai SC
    Annu Rev Biochem; 2018 Jun; 87():503-531. PubMed ID: 29925265
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural enzymology of polyketide synthases.
    Tsai SC; Ames BD
    Methods Enzymol; 2009; 459():17-47. PubMed ID: 19362634
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Docking domain-mediated subunit interactions in natural product megasynth(et)ases.
    Smith HG; Beech MJ; Lewandowski JR; Challis GL; Jenner M
    J Ind Microbiol Biotechnol; 2021 Jun; 48(3-4):. PubMed ID: 33640957
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis for chain release from the enacyloxin polyketide synthase.
    Kosol S; Gallo A; Griffiths D; Valentic TR; Masschelein J; Jenner M; de Los Santos ELC; Manzi L; Sydor PK; Rea D; Zhou S; Fülöp V; Oldham NJ; Tsai SC; Challis GL; Lewandowski JR
    Nat Chem; 2019 Oct; 11(10):913-923. PubMed ID: 31548674
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Trapping interactions between catalytic domains and carrier proteins of modular biosynthetic enzymes with chemical probes.
    Gulick AM; Aldrich CC
    Nat Prod Rep; 2018 Nov; 35(11):1156-1184. PubMed ID: 30046790
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Carrier protein structure and recognition in polyketide and nonribosomal peptide biosynthesis.
    Lai JR; Koglin A; Walsh CT
    Biochemistry; 2006 Dec; 45(50):14869-79. PubMed ID: 17154525
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deep sequencing of non-ribosomal peptide synthetases and polyketide synthases from the microbiomes of Australian marine sponges.
    Woodhouse JN; Fan L; Brown MV; Thomas T; Neilan BA
    ISME J; 2013 Sep; 7(9):1842-51. PubMed ID: 23598791
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Profiling Nonribosomal Peptide Synthetase Activities Using Chemical Proteomic Probes for Adenylation Domains.
    Ishikawa F; Konno S; Suzuki T; Dohmae N; Kakeya H
    ACS Chem Biol; 2015 Sep; 10(9):1989-97. PubMed ID: 26038981
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Engineering polyketide synthases and nonribosomal peptide synthetases.
    Williams GJ
    Curr Opin Struct Biol; 2013 Aug; 23(4):603-12. PubMed ID: 23838175
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clearing the skies over modular polyketide synthases.
    Sherman DH; Smith JL
    ACS Chem Biol; 2006 Sep; 1(8):505-9. PubMed ID: 17168537
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Type I pyridoxal 5'-phosphate dependent enzymatic domains embedded within multimodular nonribosomal peptide synthetase and polyketide synthase assembly lines.
    Milano T; Paiardini A; Grgurina I; Pascarella S
    BMC Struct Biol; 2013 Oct; 13():26. PubMed ID: 24148833
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Assembly Line Enzymology of Polyketide Biosynthesis.
    Till M; Race PR
    Methods Mol Biol; 2016; 1401():31-49. PubMed ID: 26831699
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bioactive compounds synthesized by non-ribosomal peptide synthetases and type-I polyketide synthases discovered through genome-mining and metagenomics.
    Nikolouli K; Mossialos D
    Biotechnol Lett; 2012 Aug; 34(8):1393-403. PubMed ID: 22481301
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Unique features of the ketosynthase domain in a nonribosomal peptide synthetase-polyketide synthase hybrid enzyme, tenuazonic acid synthetase 1.
    Yun CS; Nishimoto K; Motoyama T; Shimizu T; Hino T; Dohmae N; Nagano S; Osada H
    J Biol Chem; 2020 Aug; 295(33):11602-11612. PubMed ID: 32565425
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Marine Microbial Secondary Metabolites: Pathways, Evolution and Physiological Roles.
    Giordano D; Coppola D; Russo R; Denaro R; Giuliano L; Lauro FM; di Prisco G; Verde C
    Adv Microb Physiol; 2015; 66():357-428. PubMed ID: 26210108
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Polyketide Synthase Modules Redefined.
    Keatinge-Clay AT
    Angew Chem Int Ed Engl; 2017 Apr; 56(17):4658-4660. PubMed ID: 28322495
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trapping the Complex Molecular Machinery of Polyketide and Fatty Acid Synthases with Tunable Silylcyanohydrin Crosslinkers.
    Konno S; La Clair JJ; Burkart MD
    Angew Chem Int Ed Engl; 2018 Dec; 57(52):17009-17013. PubMed ID: 30379389
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protein-protein interactions in polyketide synthase-nonribosomal peptide synthetase hybrid assembly lines.
    Miyanaga A; Kudo F; Eguchi T
    Nat Prod Rep; 2018 Nov; 35(11):1185-1209. PubMed ID: 30074030
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.