114 related articles for article (PubMed ID: 31160175)
1. 3H-Imidazo[4,5-b]pyridine-6-carboxylic acid derivatives as rexinoids with reduced teratogenicity.
Takamura Y; Takahashi M; Nishii M; Shibahara O; Watanabe M; Fujihara M; Kakuta H
Bioorg Med Chem Lett; 2019 Aug; 29(15):1891-1894. PubMed ID: 31160175
[TBL] [Abstract][Full Text] [Related]
2. Methods to Assess Activity and Potency of Rexinoids Using Rapid Luciferase-Based Assays: A Case Study with NEt-TMN.
Jurutka PW; Wagner CE
Methods Mol Biol; 2019; 2019():95-108. PubMed ID: 31359391
[TBL] [Abstract][Full Text] [Related]
3. Methods to Generate an Array of Novel Rexinoids by SAR on a Potent Retinoid X Receptor Agonist: A Case Study with NEt-TMN.
Wagner CE; Jurutka PW
Methods Mol Biol; 2019; 2019():109-121. PubMed ID: 31359392
[TBL] [Abstract][Full Text] [Related]
4. Rexinoids modulate steroid and xenobiotic receptor activity by increasing its protein turnover in a calpain-dependent manner.
Pettersson F; Hanna N; Lagodich M; Dupéré-Richer D; Couture MC; Choi C; Miller WH
J Biol Chem; 2008 Aug; 283(32):21945-52. PubMed ID: 18544536
[TBL] [Abstract][Full Text] [Related]
5. Retinoid X receptor agonist elevation of serum triglycerides in rats by potentiation of retinoic acid receptor agonist induction or by action as single agents.
Standeven AM; Thacher SM; Yuan YD; Escobar M; Vuligonda V; Beard RL; Chandraratna RA
Biochem Pharmacol; 2001 Dec; 62(11):1501-9. PubMed ID: 11728386
[TBL] [Abstract][Full Text] [Related]
6. A representative retinoid X receptor antagonist UVI3003 induced teratogenesis in zebrafish embryos.
Zheng L; Xu T; Li D; Zhou J
J Appl Toxicol; 2015 Mar; 35(3):280-6. PubMed ID: 25186191
[TBL] [Abstract][Full Text] [Related]
7. Mechanism of retinoid X receptor partial agonistic action of 1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1H-benzotriazole-5-carboxylic acid and structural development to increase potency.
Ohsawa F; Yamada S; Yakushiji N; Shinozaki R; Nakayama M; Kawata K; Hagaya M; Kobayashi T; Kohara K; Furusawa Y; Fujiwara C; Ohta Y; Makishima M; Naitou H; Tai A; Yoshikawa Y; Yasui H; Kakuta H
J Med Chem; 2013 Mar; 56(5):1865-77. PubMed ID: 23391145
[TBL] [Abstract][Full Text] [Related]
8. Modeling, Synthesis, and Biological Evaluation of Potential Retinoid-X-Receptor (RXR) Selective Agonists: Analogs of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahyro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(4-isobutoxy-3-isopropylphenyl)amino)nicotinic Acid (NEt-4IB).
Jurutka PW; di Martino O; Reshi S; Mallick S; Sabir ZL; Staniszewski LJP; Warda A; Maiorella EL; Minasian A; Davidson J; Ibrahim SJ; Raban S; Haddad D; Khamisi M; Suban SL; Dawson BJ; Candia R; Ziller JW; Lee MY; Liu C; Liu W; Marshall PA; Welch JS; Wagner CE
Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830251
[TBL] [Abstract][Full Text] [Related]
9. Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening.
Yamada S; Kawasaki M; Fujihara M; Watanabe M; Takamura Y; Takioku M; Nishioka H; Takeuchi Y; Makishima M; Motoyama T; Ito S; Tokiwa H; Nakano S; Kakuta H
J Med Chem; 2019 Oct; 62(19):8809-8818. PubMed ID: 31483660
[TBL] [Abstract][Full Text] [Related]
10. Modeling, synthesis and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene).
Wagner CE; Jurutka PW; Marshall PA; Groy TL; van der Vaart A; Ziller JW; Furmick JK; Graeber ME; Matro E; Miguel BV; Tran IT; Kwon J; Tedeschi JN; Moosavi S; Danishyar A; Philp JS; Khamees RO; Jackson JN; Grupe DK; Badshah SL; Hart JW
J Med Chem; 2009 Oct; 52(19):5950-66. PubMed ID: 19791803
[TBL] [Abstract][Full Text] [Related]
11. Rexinoids isolated from Sophora tonkinensis with a gene expression profile distinct from the synthetic rexinoid bexarotene.
Inoue M; Tanabe H; Nakashima K; Ishida Y; Kotani H
J Nat Prod; 2014 Jul; 77(7):1670-7. PubMed ID: 24959987
[TBL] [Abstract][Full Text] [Related]
12. Modulating retinoid X receptor with a series of (E)-3-[4-hydroxy-3-(3-alkoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenyl]acrylic acids and their 4-alkoxy isomers.
Pérez Santín E; Germain P; Quillard F; Khanwalkar H; Rodríguez-Barrios F; Gronemeyer H; de Lera AR; Bourguet W
J Med Chem; 2009 May; 52(10):3150-8. PubMed ID: 19408900
[TBL] [Abstract][Full Text] [Related]
13. A naturally occurring rexinoid, honokiol, can serve as a regulator of various retinoid x receptor heterodimers.
Kotani H; Tanabe H; Mizukami H; Amagaya S; Inoue M
Biol Pharm Bull; 2012; 35(1):1-9. PubMed ID: 22223330
[TBL] [Abstract][Full Text] [Related]
14. Natural and Structure-based RXR Ligand Scaffolds and Their Functions.
Dominguez M; Alvarez S; de Lera AR
Curr Top Med Chem; 2017; 17(6):631-662. PubMed ID: 27320335
[TBL] [Abstract][Full Text] [Related]
15. Synthesis of
Shibahara O; Watanabe M; Yamada S; Akehi M; Sasaki T; Akahoshi A; Hanada T; Hirano H; Nakatani S; Nishioka H; Takeuchi Y; Kakuta H
J Med Chem; 2017 Aug; 60(16):7139-7145. PubMed ID: 28753292
[TBL] [Abstract][Full Text] [Related]
16. Evaluating Novel RXR Agonists That Induce ApoE and Tyrosine Hydroxylase in Cultured Human Glioblastoma Cells.
Mallick S; Marshall PA; Wagner CE; Heck MC; Sabir ZL; Sabir MS; Dussik CM; Grozic A; Kaneko I; Jurutka PW
ACS Chem Neurosci; 2021 Mar; 12(5):857-871. PubMed ID: 33570383
[TBL] [Abstract][Full Text] [Related]
17. Modulation of RXR function through ligand design.
Pérez E; Bourguet W; Gronemeyer H; de Lera AR
Biochim Biophys Acta; 2012 Jan; 1821(1):57-69. PubMed ID: 21515403
[TBL] [Abstract][Full Text] [Related]
18. Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN).
Heck MC; Wagner CE; Shahani PH; MacNeill M; Grozic A; Darwaiz T; Shimabuku M; Deans DG; Robinson NM; Salama SH; Ziller JW; Ma N; van der Vaart A; Marshall PA; Jurutka PW
J Med Chem; 2016 Oct; 59(19):8924-8940. PubMed ID: 27592633
[TBL] [Abstract][Full Text] [Related]
19. RXR partial agonist produced by side chain repositioning of alkoxy RXR full agonist retains antitype 2 diabetes activity without the adverse effects.
Kawata K; Morishita K; Nakayama M; Yamada S; Kobayashi T; Furusawa Y; Arimoto-Kobayashi S; Oohashi T; Makishima M; Naitou H; Ishitsubo E; Tokiwa H; Tai A; Kakuta H
J Med Chem; 2015 Jan; 58(2):912-26. PubMed ID: 25486327
[TBL] [Abstract][Full Text] [Related]
20. Ligand Design for Modulation of RXR Functions.
Martínez C; Souto JA; de Lera AR
Methods Mol Biol; 2019; 2019():51-72. PubMed ID: 31359388
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
