210 related articles for article (PubMed ID: 31161793)
1. Novel 2,6-diketopiperazine-derived acetohydroxamic acids as promising anti-
Fytas G; Zoidis G; Taylor MC; Kelly JM; Tsatsaroni A; Tsotinis A
Future Med Chem; 2019 Jun; 11(11):1259-1266. PubMed ID: 31161793
[No Abstract] [Full Text] [Related]
2. Lipophilic conformationally constrained spiro carbocyclic 2,6-diketopiperazine-1-acetohydroxamic acid analogues as trypanocidal and leishmanicidal agents: An extended SAR study.
Zoidis G; Tsotinis A; Tsatsaroni A; Taylor MC; Kelly JM; Efstathiou A; Smirlis D; Fytas G
Chem Biol Drug Des; 2018 Feb; 91(2):408-421. PubMed ID: 28834291
[TBL] [Abstract][Full Text] [Related]
3. Novel lipophilic acetohydroxamic acid derivatives based on conformationally constrained spiro carbocyclic 2,6-diketopiperazine scaffolds with potent trypanocidal activity.
Fytas C; Zoidis G; Tzoutzas N; Taylor MC; Fytas G; Kelly JM
J Med Chem; 2011 Jul; 54(14):5250-4. PubMed ID: 21542562
[TBL] [Abstract][Full Text] [Related]
4. Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei.
Kelly JM; Taylor MC; Horn D; Loza E; Kalvinsh I; Björkling F
Bioorg Med Chem Lett; 2012 Mar; 22(5):1886-90. PubMed ID: 22326398
[TBL] [Abstract][Full Text] [Related]
5. Anti-trypanosomal activity of doubly modified salinomycin derivatives.
Antoszczak M; Steverding D; Sulik M; Janczak J; Huczyński A
Eur J Med Chem; 2019 Jul; 173():90-98. PubMed ID: 30986574
[TBL] [Abstract][Full Text] [Related]
6. 9- and 11-Substituted 4-azapaullones are potent and selective inhibitors of African trypanosoma.
Maiwald F; Benítez D; Charquero D; Dar MA; Erdmann H; Preu L; Koch O; Hölscher C; Loaëc N; Meijer L; Comini MA; Kunick C
Eur J Med Chem; 2014 Aug; 83():274-83. PubMed ID: 24973661
[TBL] [Abstract][Full Text] [Related]
7. 3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis.
Ferrins L; Rahmani R; Sykes ML; Jones AJ; Avery VM; Teston E; Almohaywi B; Yin J; Smith J; Hyland C; White KL; Ryan E; Campbell M; Charman SA; Kaiser M; Baell JB
Eur J Med Chem; 2013 Aug; 66():450-65. PubMed ID: 23831695
[TBL] [Abstract][Full Text] [Related]
8. Assessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi.
Watts KR; Ratnam J; Ang KH; Tenney K; Compton JE; McKerrow J; Crews P
Bioorg Med Chem; 2010 Apr; 18(7):2566-74. PubMed ID: 20303767
[TBL] [Abstract][Full Text] [Related]
9. Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro.
Ferrigno F; Biancofiore I; Malancona S; Ponzi S; Paonessa G; Graziani R; Bresciani A; Gennari N; Di Marco A; Kaiser M; Summa V; Harper S; Ontoria JM
Bioorg Med Chem Lett; 2018 Dec; 28(23-24):3689-3692. PubMed ID: 30482621
[TBL] [Abstract][Full Text] [Related]
10. Potent Antitrypanosomal Activities of 3-Aminosteroids against African Trypanosomes: Investigation of Cellular Effects and of Cross-Resistance with Existing Drugs.
Nnadi CO; Ebiloma GU; Black JA; Nwodo NJ; Lemgruber L; Schmidt TJ; de Koning HP
Molecules; 2019 Jan; 24(2):. PubMed ID: 30642032
[TBL] [Abstract][Full Text] [Related]
11. Chalcone-benzoxaborole hybrid molecules as potent antitrypanosomal agents.
Qiao Z; Wang Q; Zhang F; Wang Z; Bowling T; Nare B; Jacobs RT; Zhang J; Ding D; Liu Y; Zhou H
J Med Chem; 2012 Apr; 55(7):3553-7. PubMed ID: 22360533
[TBL] [Abstract][Full Text] [Related]
12. In vitro antitrypanosomal activity of 12 low-molecular-weight antibiotics and observations of structure/activity relationships.
Iwatsuki M; Otoguro K; Ishiyama A; Namatame M; Nishihara-Tukashima A; Hashida J; Nakashima T; Masuma R; Takahashi Y; Yamada H; Omura S
J Antibiot (Tokyo); 2010 Oct; 63(10):619-22. PubMed ID: 20717119
[No Abstract] [Full Text] [Related]
13. Discovery of halo-nitrobenzamides with potential application against human African trypanosomiasis.
Hwang JY; Smithson D; Connelly M; Maier J; Zhu F; Guy KR
Bioorg Med Chem Lett; 2010 Jan; 20(1):149-52. PubMed ID: 19963377
[TBL] [Abstract][Full Text] [Related]
14. Novel pyrrolobenzoxaboroles: design, synthesis, and biological evaluation against Trypanosoma brucei.
Wu P; Zhang J; Meng Q; Nare B; Jacobs RT; Zhou H
Eur J Med Chem; 2014 Jun; 81():59-75. PubMed ID: 24826816
[TBL] [Abstract][Full Text] [Related]
15. Optimization of physicochemical properties for 4-anilinoquinazoline inhibitors of trypanosome proliferation.
Woodring JL; Bachovchin KA; Brady KG; Gallerstein MF; Erath J; Tanghe S; Leed SE; Rodriguez A; Mensa-Wilmot K; Sciotti RJ; Pollastri MP
Eur J Med Chem; 2017 Dec; 141():446-459. PubMed ID: 29049963
[TBL] [Abstract][Full Text] [Related]
16. Spiroarsoranes of second generation: evaluation of trypanocidal properties against Trypanosoma brucei brucei.
Loiseau PM; Wolf JG; Gayral P
Trop Med Parasitol; 1993 Mar; 44(1):32-6. PubMed ID: 8516630
[TBL] [Abstract][Full Text] [Related]
17. Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness.
Urbaniak MD; Tabudravu JN; Msaki A; Matera KM; Brenk R; Jaspars M; Ferguson MA
Bioorg Med Chem Lett; 2006 Nov; 16(22):5744-7. PubMed ID: 16962325
[TBL] [Abstract][Full Text] [Related]
18. Singly and doubly modified analogues of C20-epi-salinomycin: A new group of antiparasitic agents against Trypanosoma brucei.
Czerwonka D; Barcelos Y; Steverding D; Cioch A; Huczyński A; Antoszczak M
Eur J Med Chem; 2021 Jan; 209():112900. PubMed ID: 33071053
[TBL] [Abstract][Full Text] [Related]
19. Synthesis of pyrazoline-thiazolidinone hybrids with trypanocidal activity.
Havrylyuk D; Zimenkovsky B; Karpenko O; Grellier P; Lesyk R
Eur J Med Chem; 2014 Oct; 85():245-54. PubMed ID: 25089808
[TBL] [Abstract][Full Text] [Related]
20. Indirubin Analogues Inhibit
Efstathiou A; Gaboriaud-Kolar N; Myrianthopoulos V; Vougogiannopoulou K; Subota I; Aicher S; Mikros E; Bastin P; Skaltsounis AL; Soteriadou K; Smirlis D
Antimicrob Agents Chemother; 2019 Jun; 63(6):. PubMed ID: 30910902
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
