171 related articles for article (PubMed ID: 31161996)
1. Cyclic Tripeptide-based Potent and Selective Human SIRT5 Inhibitors.
Jiang Y; Zheng W
Med Chem; 2020; 16(3):358-367. PubMed ID: 31161996
[TBL] [Abstract][Full Text] [Related]
2. Cyclic tripeptide-based potent human SIRT7 inhibitors.
Li S; Wu B; Zheng W
Bioorg Med Chem Lett; 2019 Feb; 29(3):461-465. PubMed ID: 30578034
[TBL] [Abstract][Full Text] [Related]
3. A Selective Cyclic Peptidic Human SIRT5 Inhibitor.
Liu J; Huang Y; Zheng W
Molecules; 2016 Sep; 21(9):. PubMed ID: 27626398
[TBL] [Abstract][Full Text] [Related]
4. Cyclic peptide-based potent human SIRT6 inhibitors.
Liu J; Zheng W
Org Biomol Chem; 2016 Jul; 14(25):5928-35. PubMed ID: 27248480
[TBL] [Abstract][Full Text] [Related]
5. Discovery of new human Sirtuin 5 inhibitors by mimicking glutaryl-lysine substrates.
Yang F; Su H; Deng J; Mou L; Wang H; Li R; Dai QQ; Yan YH; Qian S; Wang Z; Li GB; Yang L
Eur J Med Chem; 2021 Dec; 225():113803. PubMed ID: 34461505
[TBL] [Abstract][Full Text] [Related]
6. A bicyclic pentapeptide-based highly potent and selective pan-SIRT1/2/3 inhibitor harboring N
Li R; Yan L; Sun X; Zheng W
Bioorg Med Chem; 2020 Apr; 28(7):115356. PubMed ID: 32067892
[TBL] [Abstract][Full Text] [Related]
7. A Novel Continuous Assay for the Deacylase Sirtuin 5 and Other Deacetylases.
Roessler C; Tüting C; Meleshin M; Steegborn C; Schutkowski M
J Med Chem; 2015 Sep; 58(18):7217-23. PubMed ID: 26308971
[TBL] [Abstract][Full Text] [Related]
8. Role of the Substrate Specificity-Defining Residues of Human SIRT5 in Modulating the Structural Stability and Inhibitory Features of the Enzyme.
Yu J; Haldar M; Mallik S; Srivastava DK
PLoS One; 2016; 11(3):e0152467. PubMed ID: 27023330
[TBL] [Abstract][Full Text] [Related]
9. The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5).
Zhou Y; Zhang H; He B; Du J; Lin H; Cerione RA; Hao Q
J Biol Chem; 2012 Aug; 287(34):28307-14. PubMed ID: 22767592
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of the human deacylase Sirtuin 5 by the indole GW5074.
Suenkel B; Fischer F; Steegborn C
Bioorg Med Chem Lett; 2013 Jan; 23(1):143-6. PubMed ID: 23195732
[TBL] [Abstract][Full Text] [Related]
11. Structure-based discovery of new selective small-molecule sirtuin 5 inhibitors.
Liu S; Ji S; Yu ZJ; Wang HL; Cheng X; Li WJ; Jing L; Yu Y; Chen Q; Yang LL; Li GB; Wu Y
Chem Biol Drug Des; 2018 Jan; 91(1):257-268. PubMed ID: 28756638
[TBL] [Abstract][Full Text] [Related]
12. Novel thiourea-based sirtuin inhibitory warheads.
Zang W; Hao Y; Wang Z; Zheng W
Bioorg Med Chem Lett; 2015 Aug; 25(16):3319-24. PubMed ID: 26081291
[TBL] [Abstract][Full Text] [Related]
13. Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5.
Fiorentino F; Castiello C; Mai A; Rotili D
J Med Chem; 2022 Jul; 65(14):9580-9606. PubMed ID: 35802779
[TBL] [Abstract][Full Text] [Related]
14. New ε-N-thioglutaryl-lysine derivatives as SIRT5 inhibitors: Chemical synthesis, kinetic and crystallographic studies.
Deng J; Liu ZM; Zhu KR; Cui GL; Liu LX; Yan YH; Ning XL; Yu ZJ; Li GB; Qi QR
Bioorg Chem; 2023 Jun; 135():106487. PubMed ID: 36996510
[TBL] [Abstract][Full Text] [Related]
15. Structural insights into the molecular mechanism underlying Sirt5-catalyzed desuccinylation of histone peptides.
Hang T; Chen W; Wu M; Zhan L; Wang C; Jia N; Zhang X; Zang J
Biochem J; 2019 Jan; 476(2):211-223. PubMed ID: 30523058
[TBL] [Abstract][Full Text] [Related]
16. Sirt5 deacylation activities show differential sensitivities to nicotinamide inhibition.
Fischer F; Gertz M; Suenkel B; Lakshminarasimhan M; Schutkowski M; Steegborn C
PLoS One; 2012; 7(9):e45098. PubMed ID: 23028781
[TBL] [Abstract][Full Text] [Related]
17. Simple N(ε)-thioacetyl-lysine-containing cyclic peptides exhibiting highly potent sirtuin inhibition.
Huang Y; Liu J; Yan L; Zheng W
Bioorg Med Chem Lett; 2016 Mar; 26(6):1612-1617. PubMed ID: 26874402
[TBL] [Abstract][Full Text] [Related]
18. Potent and Selective Inhibitors of Human Sirtuin 5.
Kalbas D; Liebscher S; Nowak T; Meleshin M; Pannek M; Popp C; Alhalabi Z; Bordusa F; Sippl W; Steegborn C; Schutkowski M
J Med Chem; 2018 Mar; 61(6):2460-2471. PubMed ID: 29494161
[TBL] [Abstract][Full Text] [Related]
19. Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight.
Rajabi N; Auth M; Troelsen KR; Pannek M; Bhatt DP; Fontenas M; Hirschey MD; Steegborn C; Madsen AS; Olsen CA
Angew Chem Int Ed Engl; 2017 Nov; 56(47):14836-14841. PubMed ID: 29044784
[TBL] [Abstract][Full Text] [Related]
20. Cyclic peptide-based potent and selective SIRT1/2 dual inhibitors harboring N
Chen D; Zheng W
Bioorg Med Chem Lett; 2016 Nov; 26(21):5234-5239. PubMed ID: 27707605
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
