180 related articles for article (PubMed ID: 31163697)
21. Synthesis and activity of largazole analogues with linker and macrocycle modification.
Ying Y; Liu Y; Byeon SR; Kim H; Luesch H; Hong J
Org Lett; 2008 Sep; 10(18):4021-4. PubMed ID: 18707106
[TBL] [Abstract][Full Text] [Related]
22. Synthesis and biological characterization of the histone deacetylase inhibitor largazole and C7- modified analogues.
Souto JA; Vaz E; Lepore I; Pöppler AC; Franci G; Alvarez R; Altucci L; de Lera AR
J Med Chem; 2010 Jun; 53(12):4654-67. PubMed ID: 20491440
[TBL] [Abstract][Full Text] [Related]
23. Comparative pharmacokinetic properties and antitumor activity of the marine HDACi Largazole and Largazole peptide isostere.
Pilon JL; Clausen DJ; Hansen RJ; Lunghofer PJ; Charles B; Rose BJ; Thamm DH; Gustafson DL; Bradner JE; Williams RM
Cancer Chemother Pharmacol; 2015 Apr; 75(4):671-82. PubMed ID: 25616967
[TBL] [Abstract][Full Text] [Related]
24. Largazole: from discovery to broad-spectrum therapy.
Hong J; Luesch H
Nat Prod Rep; 2012 Apr; 29(4):449-56. PubMed ID: 22334030
[TBL] [Abstract][Full Text] [Related]
25. Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.
Liu Y; Salvador LA; Byeon S; Ying Y; Kwan JC; Law BK; Hong J; Luesch H
J Pharmacol Exp Ther; 2010 Nov; 335(2):351-61. PubMed ID: 20739454
[TBL] [Abstract][Full Text] [Related]
26. Total syntheses of the histone deacetylase inhibitors largazole and 2-epi-largazole: application of N-heterocyclic carbene mediated acylations in complex molecule synthesis.
Wang B; Huang PH; Chen CS; Forsyth CJ
J Org Chem; 2011 Feb; 76(4):1140-50. PubMed ID: 21244075
[TBL] [Abstract][Full Text] [Related]
27. Synthesis, biological evaluation and molecular modeling studies of psammaplin A and its analogs as potent histone deacetylases inhibitors and cytotoxic agents.
Wen J; Bao Y; Niu Q; Liu J; Yang J; Wang W; Jiang T; Fan Y; Li K; Wang J; Zhao L; Liu D
Bioorg Med Chem Lett; 2016 Sep; 26(17):4372-6. PubMed ID: 27460171
[TBL] [Abstract][Full Text] [Related]
28. Highly ligand efficient and selective N-2-(Thioethyl)picolinamide histone deacetylase inhibitors inspired by the natural product psammaplin A.
Baud MG; Haus P; Leiser T; Meyer-Almes FJ; Fuchter MJ
ChemMedChem; 2013 Jan; 8(1):149-56. PubMed ID: 23184734
[TBL] [Abstract][Full Text] [Related]
29. Comprehensive analysis for histone acetylation of human colon cancer cells treated with a novel HDAC inhibitor.
Zhao Y; Fang X; Wang Y; Zhang J; Jiang S; Liu Z; Ma Z; Xu L; Li E; Zhang K
Curr Pharm Des; 2014; 20(11):1866-73. PubMed ID: 23888955
[TBL] [Abstract][Full Text] [Related]
30. A fluorine scan on the Zn
Zhang B; Liu J; Gao D; Yu X; Wang J; Lei X
Eur J Med Chem; 2019 Nov; 182():111672. PubMed ID: 31505452
[TBL] [Abstract][Full Text] [Related]
31. Synthesis and biological evaluation of c7-demethyl largazole analogues.
Chen F; Gao AH; Li J; Nan FJ
ChemMedChem; 2009 Aug; 4(8):1269-72. PubMed ID: 19431162
[No Abstract] [Full Text] [Related]
32. Total synthesis of the bicyclic depsipeptide HDAC inhibitors spiruchostatins A and B, 5''-epi-spiruchostatin B, FK228 (FR901228) and preliminary evaluation of their biological activity.
Narita K; Kikuchi T; Watanabe K; Takizawa T; Oguchi T; Kudo K; Matsuhara K; Abe H; Yamori T; Yoshida M; Katoh T
Chemistry; 2009 Oct; 15(42):11174-86. PubMed ID: 19760730
[TBL] [Abstract][Full Text] [Related]
33. Total synthesis and biological evaluation of largazole and derivatives with promising selectivity for cancers cells.
Zeng X; Yin B; Hu Z; Liao C; Liu J; Li S; Li Z; Nicklaus MC; Zhou G; Jiang S
Org Lett; 2010 Mar; 12(6):1368-71. PubMed ID: 20184338
[TBL] [Abstract][Full Text] [Related]
34. Total Synthesis of Thailandepsin B, a Potent HDAC Inhibitor Isolated from a Microorganism.
Narita K; Katoh T
Chem Pharm Bull (Tokyo); 2016; 64(7):913-7. PubMed ID: 27373645
[TBL] [Abstract][Full Text] [Related]
35. Enantioselective total synthesis of (+)-largazole, a potent inhibitor of histone deacetylase.
Ghosh AK; Kulkarni S
Org Lett; 2008 Sep; 10(17):3907-9. PubMed ID: 18662003
[TBL] [Abstract][Full Text] [Related]
36. Fluorescent analogs of the marine natural product psammaplin A: synthesis and biological activity.
Hentschel F; Sasse F; Lindel T
Org Biomol Chem; 2012 Sep; 10(35):7120-33. PubMed ID: 22872318
[TBL] [Abstract][Full Text] [Related]
37. Synthesis of the thiazole-thiazoline fragment of largazole analogues.
Diness F; Nielsen DS; Fairlie DP
J Org Chem; 2011 Dec; 76(23):9845-51. PubMed ID: 22032297
[TBL] [Abstract][Full Text] [Related]
38. Marine-Derived Natural Lead Compound Disulfide-Linked Dimer Psammaplin A: Biological Activity and Structural Modification.
Jing Q; Hu X; Ma Y; Mu J; Liu W; Xu F; Li Z; Bai J; Hua H; Li D
Mar Drugs; 2019 Jun; 17(7):. PubMed ID: 31252563
[TBL] [Abstract][Full Text] [Related]
39. Structure and activity of largazole, a potent antiproliferative agent from the Floridian marine cyanobacterium Symploca sp.
Taori K; Paul VJ; Luesch H
J Am Chem Soc; 2008 Feb; 130(6):1806-7. PubMed ID: 18205365
[No Abstract] [Full Text] [Related]
40. Total synthesis and stereochemical assignment of burkholdac B, a depsipeptide HDAC inhibitor.
Benelkebir H; Donlevy AM; Packham G; Ganesan A
Org Lett; 2011 Dec; 13(24):6334-7. PubMed ID: 22091906
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
