362 related articles for article (PubMed ID: 31165654)
1. Developments with multi-target drugs for Alzheimer's disease: an overview of the current discovery approaches.
González JF; Alcántara AR; Doadrio AL; Sánchez-Montero JM
Expert Opin Drug Discov; 2019 Sep; 14(9):879-891. PubMed ID: 31165654
[No Abstract] [Full Text] [Related]
2. Multi-Target Drug Candidates for Multifactorial Alzheimer's Disease: AChE and NMDAR as Molecular Targets.
Uddin MS; Al Mamun A; Kabir MT; Ashraf GM; Bin-Jumah MN; Abdel-Daim MM
Mol Neurobiol; 2021 Jan; 58(1):281-303. PubMed ID: 32935230
[TBL] [Abstract][Full Text] [Related]
3. Chromones: privileged scaffolds for the production of multi-target-directed-ligand agents for the treatment of Alzheimer's disease.
Silva CFM; Pinto DCGA; Silva AMS
Expert Opin Drug Discov; 2018 Dec; 13(12):1141-1151. PubMed ID: 30430870
[No Abstract] [Full Text] [Related]
4. Topical Discoveries on Multi-Target Approach to Manage Alzheimer's Disease.
Batool A; Kamal MA; Rizvi SMD; Rashid S
Curr Drug Metab; 2018; 19(8):704-713. PubMed ID: 29512457
[TBL] [Abstract][Full Text] [Related]
5. A molecular approach in drug development for Alzheimer's disease.
Agatonovic-Kustrin S; Kettle C; Morton DW
Biomed Pharmacother; 2018 Oct; 106():553-565. PubMed ID: 29990843
[TBL] [Abstract][Full Text] [Related]
6. Have there been improvements in Alzheimer's disease drug discovery over the past 5 years?
Cacabelos R
Expert Opin Drug Discov; 2018 Jun; 13(6):523-538. PubMed ID: 29607687
[TBL] [Abstract][Full Text] [Related]
7. Changing Paradigm from one Target one Ligand Towards Multi-target Directed Ligand Design for Key Drug Targets of Alzheimer Disease: An Important Role of In Silico Methods in Multi-target Directed Ligands Design.
Kumar A; Tiwari A; Sharma A
Curr Neuropharmacol; 2018; 16(6):726-739. PubMed ID: 29542413
[TBL] [Abstract][Full Text] [Related]
8. Target Enzyme in Alzheimer's Disease: Acetylcholinesterase Inhibitors.
Saxena M; Dubey R
Curr Top Med Chem; 2019; 19(4):264-275. PubMed ID: 30706815
[TBL] [Abstract][Full Text] [Related]
9. In silico Structure-based Identification of Novel Acetylcholinesterase Inhibitors Against Alzheimer's Disease.
Iman K; Mirza MU; Mazhar N; Vanmeert M; Irshad I; Kamal MA
CNS Neurol Disord Drug Targets; 2018 Apr; 17(1):54-68. PubMed ID: 29336270
[TBL] [Abstract][Full Text] [Related]
10. Alzheimer's Disease, the "One-Molecule, One-Target" Paradigm, and the Multitarget Directed Ligand Approach.
Oset-Gasque MJ; Marco-Contelles J
ACS Chem Neurosci; 2018 Mar; 9(3):401-403. PubMed ID: 29465220
[TBL] [Abstract][Full Text] [Related]
11. Anti-cholinesterase hybrids as multi-target-directed ligands against Alzheimer's disease (1998-2018).
Mishra P; Kumar A; Panda G
Bioorg Med Chem; 2019 Mar; 27(6):895-930. PubMed ID: 30744931
[TBL] [Abstract][Full Text] [Related]
12. Multi-potent Natural Scaffolds Targeting Amyloid Cascade: In Search of Alzheimer's Disease Therapeutics.
Chakraborty S
Curr Top Med Chem; 2017; 17(31):3336-3348. PubMed ID: 29345580
[TBL] [Abstract][Full Text] [Related]
13. Acetylcholinesterase inhibitors for the treatment of Alzheimer's disease - a patent review (2016-present).
Bortolami M; Rocco D; Messore A; Di Santo R; Costi R; Madia VN; Scipione L; Pandolfi F
Expert Opin Ther Pat; 2021 May; 31(5):399-420. PubMed ID: 33428491
[No Abstract] [Full Text] [Related]
14. Designing Second Generation Anti-Alzheimer Compounds as Inhibitors of Human Acetylcholinesterase: Computational Screening of Synthetic Molecules and Dietary Phytochemicals.
Amat-Ur-Rasool H; Ahmed M
PLoS One; 2015; 10(9):e0136509. PubMed ID: 26325402
[TBL] [Abstract][Full Text] [Related]
15. Old and new acetylcholinesterase inhibitors for Alzheimer's disease.
Galimberti D; Scarpini E
Expert Opin Investig Drugs; 2016 Oct; 25(10):1181-7. PubMed ID: 27459153
[TBL] [Abstract][Full Text] [Related]
16. Recent advances in acetylcholinesterase Inhibitors and Reactivators: an update on the patent literature (2012-2015).
McHardy SF; Wang HL; McCowen SV; Valdez MC
Expert Opin Ther Pat; 2017 Apr; 27(4):455-476. PubMed ID: 27967267
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
Dias Viegas FP; de Freitas Silva M; Divino da Rocha M; Castelli MR; Riquiel MM; Machado RP; Vaz SM; Simões de Lima LM; Mancini KC; Marques de Oliveira PC; Morais ÉP; Gontijo VS; da Silva FMR; D'Alincourt da Fonseca Peçanha D; Castro NG; Neves GA; Giusti-Paiva A; Vilela FC; Orlandi L; Camps I; Veloso MP; Leomil Coelho LF; Ionta M; Ferreira-Silva GÁ; Pereira RM; Dardenne LE; Guedes IA; de Oliveira Carneiro Junior W; Quaglio Bellozi PM; Pinheiro de Oliveira AC; Ferreira FF; Pruccoli L; Tarozzi A; Viegas C
Eur J Med Chem; 2018 Mar; 147():48-65. PubMed ID: 29421570
[TBL] [Abstract][Full Text] [Related]
18. Tea polyphenols as multi-target therapeutics for Alzheimer's disease: An in silico study.
Mazumder MK; Choudhury S
Med Hypotheses; 2019 Apr; 125():94-99. PubMed ID: 30902161
[TBL] [Abstract][Full Text] [Related]
19. Discovery of anti-Alzheimer agents: current ligand-based approaches toward the design of acetylcholinesterase inhibitors.
Speck-Planche A; Luan F; Cordeiro MN
Mini Rev Med Chem; 2012 Jun; 12(6):583-91. PubMed ID: 22587771
[TBL] [Abstract][Full Text] [Related]
20. [Design of acetylcholinesterase inhibitor for Alzheimer's disease therapy: from multi-binding site inhibitors to multi-target directed ligands].
Yang WC; Sun Q; Yu NX; Zhu XL; Yang GF
Yao Xue Xue Bao; 2012 Mar; 47(3):313-21. PubMed ID: 22645754
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
