These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
440 related articles for article (PubMed ID: 31165955)
1. Identification of novel and potent small-molecule inhibitors of tubulin with antitumor activities by virtual screening and biological evaluations. Liu G; Jiao Y; Huang C; Chang P J Comput Aided Mol Des; 2019 Jul; 33(7):659-664. PubMed ID: 31165955 [TBL] [Abstract][Full Text] [Related]
2. Ligand- and structural-based discovery of potential small molecules that target the colchicine site of tubulin for cancer treatment. Guo Q; Zhang H; Deng Y; Zhai S; Jiang Z; Zhu D; Wang L Eur J Med Chem; 2020 Jun; 196():112328. PubMed ID: 32320841 [TBL] [Abstract][Full Text] [Related]
3. Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes. Majcher U; Urbaniak A; Maj E; Moshari M; Delgado M; Wietrzyk J; Bartl F; Chambers TC; Tuszynski JA; Huczyński A Bioorg Chem; 2018 Dec; 81():553-566. PubMed ID: 30248507 [TBL] [Abstract][Full Text] [Related]
4. The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site. Boichuk S; Galembikova A; Syuzov K; Dunaev P; Bikinieva F; Aukhadieva A; Zykova S; Igidov N; Gankova K; Novikova M; Kopnin P Molecules; 2021 Sep; 26(19):. PubMed ID: 34641324 [TBL] [Abstract][Full Text] [Related]
5. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition. Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790 [TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors. Liu R; Zhang S; Huang M; Guo Z; Li L; Li M; Wu L; Guan Q; Zhang W Bioorg Chem; 2021 Oct; 115():105220. PubMed ID: 34352709 [TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors. Behbahani FS; Tabeshpour J; Mirzaei S; Golmakaniyoon S; Tayarani-Najaran Z; Ghasemi A; Ghodsi R Arch Pharm (Weinheim); 2019 Jun; 352(6):e1800307. PubMed ID: 31012156 [TBL] [Abstract][Full Text] [Related]
8. New indole-based chalconoids as tubulin-targeting antiproliferative agents. Mirzaei H; Shokrzadeh M; Modanloo M; Ziar A; Riazi GH; Emami S Bioorg Chem; 2017 Dec; 75():86-98. PubMed ID: 28922629 [TBL] [Abstract][Full Text] [Related]
9. Tubulin inhibitor identification by bioactive conformation alignment pharmacophore-guided virtual screening. Nagarajan S; Choi MJ; Cho YS; Min SJ; Keum G; Kim SJ; Lee CS; Pae AN Chem Biol Drug Des; 2015 Nov; 86(5):998-1016. PubMed ID: 25845798 [TBL] [Abstract][Full Text] [Related]
10. Structure-based virtual screening of novel tubulin inhibitors and their characterization as anti-mitotic agents. Kim ND; Park ES; Kim YH; Moon SK; Lee SS; Ahn SK; Yu DY; No KT; Kim KH Bioorg Med Chem; 2010 Oct; 18(19):7092-100. PubMed ID: 20810285 [TBL] [Abstract][Full Text] [Related]
11. Discovery of novel N-benzylbenzamide derivatives as tubulin polymerization inhibitors with potent antitumor activities. Zhu H; Li W; Shuai W; Liu Y; Yang L; Tan Y; Zheng T; Yao H; Xu J; Zhu Z; Yang DH; Chen ZS; Xu S Eur J Med Chem; 2021 Apr; 216():113316. PubMed ID: 33676300 [TBL] [Abstract][Full Text] [Related]
12. Quinolin-6-Yloxyacetamides Are Microtubule Destabilizing Agents That Bind to the Colchicine Site of Tubulin. Sharma A; Sáez-Calvo G; Olieric N; de Asís Balaguer F; Barasoain I; Lamberth C; Díaz JF; Steinmetz MO Int J Mol Sci; 2017 Jun; 18(7):. PubMed ID: 28640209 [TBL] [Abstract][Full Text] [Related]
13. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo. Cui YJ; Ma CC; Zhang CM; Tang LQ; Liu ZP Eur J Med Chem; 2020 Feb; 187():111968. PubMed ID: 31865012 [TBL] [Abstract][Full Text] [Related]
14. Discovery of potent microtubule-destabilizing agents targeting for colchicine site by virtual screening, biological evaluation, and molecular dynamics simulation. Zhang H; Luo QQ; Hu ML; Wang N; Qi HZ; Zhang HR; Ding L Eur J Pharm Sci; 2023 Jan; 180():106340. PubMed ID: 36435355 [TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site. Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162 [TBL] [Abstract][Full Text] [Related]
16. Discovery of microtubule stabilizers with novel scaffold structures based on virtual screening, biological evaluation, and molecular dynamics simulation. Mao J; Luo QQ; Zhang HR; Zheng XH; Shen C; Qi HZ; Hu ML; Zhang H Chem Biol Interact; 2022 Jan; 352():109784. PubMed ID: 34932952 [TBL] [Abstract][Full Text] [Related]
17. Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway. Song J; Wang SH; Song CH; Zhang WX; Zhu JX; Tian XY; Fu XJ; Xu Y; Jin CY; Zhang SY Eur J Med Chem; 2022 Oct; 240():114583. PubMed ID: 35834904 [TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors. Qin YJ; Li YJ; Jiang AQ; Yang MR; Zhu QZ; Dong H; Zhu HL Eur J Med Chem; 2015 Apr; 94():447-57. PubMed ID: 25828827 [TBL] [Abstract][Full Text] [Related]
19. Design and synthesis of novel 5-(4-chlorophenyl)furan derivatives with inhibitory activity on tubulin polymerization. Moussa SA; A Osman EE; Eid NM; Abou-Seri SM; El Moghazy SM Future Med Chem; 2018 Aug; 10(16):1907-1924. PubMed ID: 29966433 [TBL] [Abstract][Full Text] [Related]
20. Novel Benzo[B]Furans with Anti-Microtubule Activity Upregulate Expression of Apoptotic Genes and Arrest Leukemia Cells in G2/M Phase. Królewska-Golińska K; Cieślak MJ; Sobczak M; Dolot R; Radzikowska-Cieciura E; Napiórkowska M; Wybrańska I; Nawrot B Anticancer Agents Med Chem; 2019; 19(3):375-388. PubMed ID: 30465514 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]