BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 31171721)

  • 1. Peroxynitrite supports a metabolic reprogramming in merlin-deficient Schwann cells and promotes cell survival.
    Pestoni JC; Klingeman Plati S; Valdivia Camacho OD; Fuse MA; Onatunde M; Sparrow NA; Karajannis MA; Fernández-Valle C; Franco MC
    J Biol Chem; 2019 Jul; 294(30):11354-11368. PubMed ID: 31171721
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Generation and Use of Merlin-Deficient Human Schwann Cells for a High-Throughput Chemical Genomics Screening Assay.
    Petrilli AM; Fernández-Valle C
    Methods Mol Biol; 2018; 1739():161-173. PubMed ID: 29546707
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cells.
    Petrilli AM; Garcia J; Bott M; Klingeman Plati S; Dinh CT; Bracho OR; Yan D; Zou B; Mittal R; Telischi FF; Liu XZ; Chang LS; Welling DB; Copik AJ; Fernández-Valle C
    Oncotarget; 2017 May; 8(19):31666-31681. PubMed ID: 28427224
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2).
    Hawley E; Gehlhausen J; Karchugina S; Chow HY; Araiza-Olivera D; Radu M; Smith A; Burks C; Jiang L; Li X; Bessler W; Masters A; Edwards D; Burgin C; Jones D; Yates C; Clapp DW; Chernoff J; Park SJ
    Hum Mol Genet; 2021 Aug; 30(17):1607-1617. PubMed ID: 34075397
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis.
    Petrilli A; Bott M; Fernández-Valle C
    Oncotarget; 2013 Dec; 4(12):2354-65. PubMed ID: 24259290
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of the NF2 gene and merlin occur by the tumorlet stage of schwannoma development in neurofibromatosis 2.
    Stemmer-Rachamimov AO; Ino Y; Lim ZY; Jacoby LB; MacCollin M; Gusella JF; Ramesh V; Louis DN
    J Neuropathol Exp Neurol; 1998 Dec; 57(12):1164-7. PubMed ID: 9862639
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LIM domain kinases as potential therapeutic targets for neurofibromatosis type 2.
    Petrilli A; Copik A; Posadas M; Chang LS; Welling DB; Giovannini M; Fernández-Valle C
    Oncogene; 2014 Jul; 33(27):3571-82. PubMed ID: 23934191
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2-associated schwannomas reveals differences in efficacy and drug resistance development.
    Fuse MA; Dinh CT; Vitte J; Kirkpatrick J; Mindos T; Plati SK; Young JI; Huang J; Carlstedt A; Franco MC; Brnjos K; Nagamoto J; Petrilli AM; Copik AJ; Soulakova JN; Bracho O; Yan D; Mittal R; Shen R; Telischi FF; Morrison H; Giovannini M; Liu XZ; Chang LS; Fernandez-Valle C
    Neuro Oncol; 2019 Mar; 21(4):486-497. PubMed ID: 30615146
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Merlin knockdown in human Schwann cells: clues to vestibular schwannoma tumorigenesis.
    Ahmad Z; Brown CM; Patel AK; Ryan AF; Ongkeko R; Doherty JK
    Otol Neurotol; 2010 Apr; 31(3):460-6. PubMed ID: 20195187
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cellular mechanisms of heterogeneity in NF2-mutant schwannoma.
    Chiasson-MacKenzie C; Vitte J; Liu CH; Wright EA; Flynn EA; Stott SL; Giovannini M; McClatchey AI
    Nat Commun; 2023 Mar; 14(1):1559. PubMed ID: 36944680
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interaction between two isoforms of the NF2 tumor suppressor protein, merlin, and between merlin and ezrin, suggests modulation of ERM proteins by merlin.
    Meng JJ; Lowrie DJ; Sun H; Dorsey E; Pelton PD; Bashour AM; Groden J; Ratner N; Ip W
    J Neurosci Res; 2000 Nov; 62(4):491-502. PubMed ID: 11070492
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential gene expression between human schwannoma and control Schwann cells.
    Hanemann CO; Bartelt-Kirbach B; Diebold R; Kämpchen K; Langmesser S; Utermark T
    Neuropathol Appl Neurobiol; 2006 Dec; 32(6):605-14. PubMed ID: 17083475
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combination Therapy with c-Met and Src Inhibitors Induces Caspase-Dependent Apoptosis of Merlin-Deficient Schwann Cells and Suppresses Growth of Schwannoma Cells.
    Fuse MA; Plati SK; Burns SS; Dinh CT; Bracho O; Yan D; Mittal R; Shen R; Soulakova JN; Copik AJ; Liu XZ; Telischi FF; Chang LS; Franco MC; Fernandez-Valle C
    Mol Cancer Ther; 2017 Nov; 16(11):2387-2398. PubMed ID: 28775147
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Neurofibromatosis type 2 (NF2)].
    Araki N; Takeshima H; Saya H
    Gan To Kagaku Ryoho; 1997 Sep; 24(11):1427-31. PubMed ID: 9309136
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduced apoptosis rates in human schwannomas.
    Utermark T; Kaempchen K; Antoniadis G; Hanemann CO
    Brain Pathol; 2005 Jan; 15(1):17-22. PubMed ID: 15779232
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Merlin status regulates p75(NTR) expression and apoptotic signaling in Schwann cells following nerve injury.
    Ahmad I; Fernando A; Gurgel R; Jason Clark J; Xu L; Hansen MR
    Neurobiol Dis; 2015 Oct; 82():114-122. PubMed ID: 26057084
    [TBL] [Abstract][Full Text] [Related]  

  • 17. mTORC1 inhibition delays growth of neurofibromatosis type 2 schwannoma.
    Giovannini M; Bonne NX; Vitte J; Chareyre F; Tanaka K; Adams R; Fisher LM; Valeyrie-Allanore L; Wolkenstein P; Goutagny S; Kalamarides M
    Neuro Oncol; 2014 Apr; 16(4):493-504. PubMed ID: 24414536
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NF2: the wizardry of merlin.
    Xiao GH; Chernoff J; Testa JR
    Genes Chromosomes Cancer; 2003 Dec; 38(4):389-99. PubMed ID: 14566860
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2.
    Prabhakar S; Beauchamp RL; Cheah PS; Yoshinaga A; Haidar EA; Lule S; Mani G; Maalouf K; Stemmer-Rachamimov A; Jung DH; Welling DB; Giovannini M; Plotkin SR; Maguire CA; Ramesh V; Breakefield XO
    Mol Ther Methods Clin Dev; 2022 Sep; 26():169-180. PubMed ID: 35846573
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Point mutation in the NF2 gene of HEI-193 human schwannoma cells results in the expression of a merlin isoform with attenuated growth suppressive activity.
    Lepont P; Stickney JT; Foster LA; Meng JJ; Hennigan RF; Ip W
    Mutat Res; 2008 Jan; 637(1-2):142-51. PubMed ID: 17868749
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.