These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 31173720)

  • 1. Methylation of Histone H3K79 by Dot1L Requires Multiple Contacts with the Ubiquitinated Nucleosome.
    Zhang Y; Kutateladze TG
    Mol Cell; 2019 Jun; 74(5):862-863. PubMed ID: 31173720
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase.
    Jang S; Kang C; Yang HS; Jung T; Hebert H; Chung KY; Kim SJ; Hohng S; Song JJ
    Genes Dev; 2019 Jun; 33(11-12):620-625. PubMed ID: 30923167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase.
    Anderson CJ; Baird MR; Hsu A; Barbour EH; Koyama Y; Borgnia MJ; McGinty RK
    Cell Rep; 2019 Feb; 26(7):1681-1690.e5. PubMed ID: 30759380
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
    Worden EJ; Hoffmann NA; Hicks CW; Wolberger C
    Cell; 2019 Mar; 176(6):1490-1501.e12. PubMed ID: 30765112
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination.
    Valencia-Sánchez MI; De Ioannes P; Wang M; Vasilyev N; Chen R; Nudler E; Armache JP; Armache KJ
    Mol Cell; 2019 Jun; 74(5):1010-1019.e6. PubMed ID: 30981630
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B.
    McGinty RK; Köhn M; Chatterjee C; Chiang KP; Pratt MR; Muir TW
    ACS Chem Biol; 2009 Nov; 4(11):958-68. PubMed ID: 19799466
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation and regulation of H2B-Ubiquitin-dependent histone methyltransferases.
    Worden EJ; Wolberger C
    Curr Opin Struct Biol; 2019 Dec; 59():98-106. PubMed ID: 31229920
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DOT1L activity in leukemia cells requires interaction with ubiquitylated H2B that promotes productive nucleosome binding.
    Spangler CJ; Yadav SP; Li D; Geil CN; Smith CB; Wang GG; Lee TH; McGinty RK
    Cell Rep; 2022 Feb; 38(7):110369. PubMed ID: 35172132
    [TBL] [Abstract][Full Text] [Related]  

  • 9. H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
    Ai H; Sun M; Liu A; Sun Z; Liu T; Cao L; Liang L; Qu Q; Li Z; Deng Z; Tong Z; Chu G; Tian X; Deng H; Zhao S; Li JB; Lou Z; Liu L
    Nat Chem Biol; 2022 Sep; 18(9):972-980. PubMed ID: 35739357
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The upstreams and downstreams of H3K79 methylation by DOT1L.
    Vlaming H; van Leeuwen F
    Chromosoma; 2016 Sep; 125(4):593-605. PubMed ID: 26728620
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Histone monoubiquitylation position determines specificity and direction of enzymatic cross-talk with histone methyltransferases Dot1L and PRC2.
    Whitcomb SJ; Fierz B; McGinty RK; Holt M; Ito T; Muir TW; Allis CD
    J Biol Chem; 2012 Jul; 287(28):23718-25. PubMed ID: 22619169
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dot1L mediated histone H3 lysine79 methylation is essential to meiosis progression in mouse oocytes.
    Wang X; Gao W; Ma X; Wang X; Song C; Huang X; Liu H
    Neuro Endocrinol Lett; 2014; 35(6):523-30. PubMed ID: 25433842
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The engagement of histone lysine methyltransferases with nucleosomes: structural basis, regulatory mechanisms, and therapeutic implications.
    Li Y; Ge K; Li T; Cai R; Chen Y
    Protein Cell; 2023 Apr; 14(3):165-179. PubMed ID: 37051671
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo.
    Vlaming H; van Welsem T; de Graaf EL; Ontoso D; Altelaar AF; San-Segundo PA; Heck AJ; van Leeuwen F
    EMBO Rep; 2014 Oct; 15(10):1077-84. PubMed ID: 25141862
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histone H2B ubiquitination and beyond: Regulation of nucleosome stability, chromatin dynamics and the trans-histone H3 methylation.
    Chandrasekharan MB; Huang F; Sun ZW
    Epigenetics; 2010 Aug; 5(6):460-8. PubMed ID: 20523115
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deficiency of H3K79 histone methyltransferase Dot1-like protein (DOT1L) inhibits cell proliferation.
    Kim W; Kim R; Park G; Park JW; Kim JE
    J Biol Chem; 2012 Feb; 287(8):5588-99. PubMed ID: 22190683
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evidence that ubiquitylated H2B corrals hDot1L on the nucleosomal surface to induce H3K79 methylation.
    Zhou L; Holt MT; Ohashi N; Zhao A; Müller MM; Wang B; Muir TW
    Nat Commun; 2016 Feb; 7():10589. PubMed ID: 26830124
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation.
    McGinty RK; Kim J; Chatterjee C; Roeder RG; Muir TW
    Nature; 2008 Jun; 453(7196):812-6. PubMed ID: 18449190
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
    Chen S; Yang Z; Wilkinson AW; Deshpande AJ; Sidoli S; Krajewski K; Strahl BD; Garcia BA; Armstrong SA; Patel DJ; Gozani O
    Mol Cell; 2015 Oct; 60(2):319-27. PubMed ID: 26439302
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Trypanosome H2Bv replaces H2B in nucleosomes enriched for H3 K4 and K76 trimethylation.
    Mandava V; Janzen CJ; Cross GA
    Biochem Biophys Res Commun; 2008 Apr; 368(4):846-51. PubMed ID: 18261990
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.