BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

287 related articles for article (PubMed ID: 31174569)

  • 1. NEO212 induces mitochondrial apoptosis and impairs autophagy flux in ovarian cancer.
    Song X; Liu L; Chang M; Geng X; Wang X; Wang W; Chen TC; Xie L; Song X
    J Exp Clin Cancer Res; 2019 Jun; 38(1):239. PubMed ID: 31174569
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel temozolomide analog, NEO212, with enhanced activity against MGMT-positive melanoma in vitro and in vivo.
    Chen TC; Cho HY; Wang W; Nguyen J; Jhaveri N; Rosenstein-Sisson R; Hofman FM; Schönthal AH
    Cancer Lett; 2015 Mar; 358(2):144-151. PubMed ID: 25524552
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NEO212, temozolomide conjugated to perillyl alcohol, is a novel drug for effective treatment of a broad range of temozolomide-resistant gliomas.
    Cho HY; Wang W; Jhaveri N; Lee DJ; Sharma N; Dubeau L; Schönthal AH; Hofman FM; Chen TC
    Mol Cancer Ther; 2014 Aug; 13(8):2004-17. PubMed ID: 24994771
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Temozolomide-Perillyl alcohol conjugate impairs Mitophagy flux by inducing lysosomal dysfunction in non-small cell lung Cancer cells and sensitizes them to irradiation.
    Chang M; Song X; Geng X; Wang X; Wang W; Chen TC; Xie L; Song X
    J Exp Clin Cancer Res; 2018 Oct; 37(1):250. PubMed ID: 30326943
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Advanced glycation end-products suppress autophagic flux in podocytes by activating mammalian target of rapamycin and inhibiting nuclear translocation of transcription factor EB.
    Zhao X; Chen Y; Tan X; Zhang L; Zhang H; Li Z; Liu S; Li R; Lin T; Liao R; Zhang Q; Dong W; Shi W; Liang X
    J Pathol; 2018 Jun; 245(2):235-248. PubMed ID: 29570219
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Docetaxel enhances lysosomal function through TFEB activation.
    Zhang J; Wang J; Wong YK; Sun X; Chen Y; Wang L; Yang L; Lu L; Shen HM; Huang D
    Cell Death Dis; 2018 May; 9(6):614. PubMed ID: 29795139
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel drug conjugate, NEO212, targeting proneural and mesenchymal subtypes of patient-derived glioma cancer stem cells.
    Jhaveri N; Agasse F; Armstrong D; Peng L; Commins D; Wang W; Rosenstein-Sisson R; Vaikari VP; Santiago SV; Santos T; Chen L; Schönthal AH; Chen TC; Hofman FM
    Cancer Lett; 2016 Feb; 371(2):240-50. PubMed ID: 26683773
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chemotherapeutic effect of a novel temozolomide analog on nasopharyngeal carcinoma in vitro and in vivo.
    Chen TC; Cho HY; Wang W; Wetzel SJ; Singh A; Nguyen J; Hofman FM; Schönthal AH
    J Biomed Sci; 2015 Aug; 22(1):71. PubMed ID: 26282951
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Therapeutic effect of TMZ-POH on human nasopharyngeal carcinoma depends on reactive oxygen species accumulation.
    Xie L; Song X; Guo W; Wang X; Wei L; Li Y; Lv L; Wang W; Chen TC; Song X
    Oncotarget; 2016 Jan; 7(2):1651-62. PubMed ID: 26625208
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation.
    Pan H; Wang Y; Na K; Wang Y; Wang L; Li Z; Guo C; Guo D; Wang X
    Cell Death Dis; 2019 Jun; 10(6):456. PubMed ID: 31186406
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 6-Hydroxydopamine induces autophagic flux dysfunction by impairing transcription factor EB activation and lysosomal function in dopaminergic neurons and SH-SY5Y cells.
    He X; Yuan W; Li Z; Hou Y; Liu F; Feng J
    Toxicol Lett; 2018 Feb; 283():58-68. PubMed ID: 29170033
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Temozolomide-perillyl alcohol conjugate induced reactive oxygen species accumulation contributes to its cytotoxicity against non-small cell lung cancer.
    Song X; Xie L; Wang X; Zeng Q; Chen TC; Wang W; Song X
    Sci Rep; 2016 Mar; 6():22762. PubMed ID: 26949038
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oblongifolin C suppresses lysosomal function independently of TFEB nuclear translocation.
    Wu M; Lao YZ; Tan HS; Lu G; Ren Y; Zheng ZQ; Yi J; Fu WW; Shen HM; Xu HX
    Acta Pharmacol Sin; 2019 Jul; 40(7):929-937. PubMed ID: 30333555
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of mitochondria- and endoplasmic reticulum stress-mediated autophagy augments temozolomide-induced apoptosis in glioma cells.
    Lin CJ; Lee CC; Shih YL; Lin CH; Wang SH; Chen TH; Shih CM
    PLoS One; 2012; 7(6):e38706. PubMed ID: 22745676
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxidative Stress by Monoamine Oxidase-A Impairs Transcription Factor EB Activation and Autophagosome Clearance, Leading to Cardiomyocyte Necrosis and Heart Failure.
    Santin Y; Sicard P; Vigneron F; Guilbeau-Frugier C; Dutaur M; Lairez O; Couderc B; Manni D; Korolchuk VI; Lezoualc'h F; Parini A; Mialet-Perez J
    Antioxid Redox Signal; 2016 Jul; 25(1):10-27. PubMed ID: 26959532
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer.
    Zhang L; Qiang P; Yu J; Miao Y; Chen Z; Qu J; Zhao Q; Chen Z; Liu Y; Yao X; Liu B; Cui L; Jing H; Sun G
    Autophagy; 2019 Mar; 15(3):391-406. PubMed ID: 30145925
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Critical Role of TFEB-Mediated Lysosomal Biogenesis in Alcohol-Induced Pancreatitis in Mice and Humans.
    Wang S; Ni HM; Chao X; Ma X; Kolodecik T; De Lisle R; Ballabio A; Pacher P; Ding WX
    Cell Mol Gastroenterol Hepatol; 2020; 10(1):59-81. PubMed ID: 31987928
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
    Viola G; Cecconet L; Leszl A; Basso G; Brun P; Salvador A; Dall'Acqua F; Diana P; Barraja P; Cirrincione G
    Cancer Chemother Pharmacol; 2009 Nov; 64(6):1235-51. PubMed ID: 19363609
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery in mouse neuroblastoma cells.
    Li M; Pi H; Yang Z; Reiter RJ; Xu S; Chen X; Chen C; Zhang L; Yang M; Li Y; Guo P; Li G; Tu M; Tian L; Xie J; He M; Lu Y; Zhong M; Zhang Y; Yu Z; Zhou Z
    J Pineal Res; 2016 Oct; 61(3):353-69. PubMed ID: 27396692
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Morusin induces paraptosis-like cell death through mitochondrial calcium overload and dysfunction in epithelial ovarian cancer.
    Xue J; Li R; Zhao X; Ma C; Lv X; Liu L; Liu P
    Chem Biol Interact; 2018 Mar; 283():59-74. PubMed ID: 29421517
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.