These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

266 related articles for article (PubMed ID: 31176671)

  • 1. Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates.
    Cunningham CN; Williams JM; Knupp J; Arunagiri A; Arvan P; Tsai B
    Mol Cell; 2019 Aug; 75(3):442-456.e4. PubMed ID: 31176671
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones.
    Chen YJ; Knupp J; Arunagiri A; Haataja L; Arvan P; Tsai B
    Nat Commun; 2021 Oct; 12(1):5991. PubMed ID: 34645803
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chaperone-Driven Degradation of a Misfolded Proinsulin Mutant in Parallel With Restoration of Wild-Type Insulin Secretion.
    Cunningham CN; He K; Arunagiri A; Paton AW; Paton JC; Arvan P; Tsai B
    Diabetes; 2017 Mar; 66(3):741-753. PubMed ID: 28028074
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Endoplasmic reticulum tubules limit the size of misfolded protein condensates.
    Parashar S; Chidambaram R; Chen S; Liem CR; Griffis E; Lambert GG; Shaner NC; Wortham M; Hay JC; Ferro-Novick S
    Elife; 2021 Sep; 10():. PubMed ID: 34467852
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The ER transmembrane protein PGRMC1 recruits misfolded proteins for reticulophagic clearance.
    Knupp J; Chen YJ; Arunagiri A; Haataja L; Arvan P; Tsai B
    Autophagy; 2022 Jan; 18(1):228-230. PubMed ID: 34779709
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.
    Arunagiri A; Haataja L; Cunningham CN; Shrestha N; Tsai B; Qi L; Liu M; Arvan P
    Ann N Y Acad Sci; 2018 Apr; 1418(1):5-19. PubMed ID: 29377149
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PDI reductase acts on Akita mutant proinsulin to initiate retrotranslocation along the Hrd1/Sel1L-p97 axis.
    He K; Cunningham CN; Manickam N; Liu M; Arvan P; Tsai B
    Mol Biol Cell; 2015 Oct; 26(19):3413-23. PubMed ID: 26269577
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reticulon protects the integrity of the ER membrane during ER escape of large macromolecular protein complexes.
    Chen YJ; Williams JM; Arvan P; Tsai B
    J Cell Biol; 2020 Feb; 219(2):. PubMed ID: 31895406
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutant INS-gene induced diabetes of youth: proinsulin cysteine residues impose dominant-negative inhibition on wild-type proinsulin transport.
    Liu M; Haataja L; Wright J; Wickramasinghe NP; Hua QX; Phillips NF; Barbetti F; Weiss MA; Arvan P
    PLoS One; 2010 Oct; 5(10):e13333. PubMed ID: 20948967
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress.
    Wright J; Birk J; Haataja L; Liu M; Ramming T; Weiss MA; Appenzeller-Herzog C; Arvan P
    J Biol Chem; 2013 Oct; 288(43):31010-8. PubMed ID: 24022479
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disulfide Mispairing During Proinsulin Folding in the Endoplasmic Reticulum.
    Haataja L; Manickam N; Soliman A; Tsai B; Liu M; Arvan P
    Diabetes; 2016 Apr; 65(4):1050-60. PubMed ID: 26822090
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biological behaviors of mutant proinsulin contribute to the phenotypic spectrum of diabetes associated with insulin gene mutations.
    Wang H; Saint-Martin C; Xu J; Ding L; Wang R; Feng W; Liu M; Shu H; Fan Z; Haataja L; Arvan P; Bellanné-Chantelot C; Cui J; Huang Y
    Mol Cell Endocrinol; 2020 Dec; 518():111025. PubMed ID: 32916194
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biosynthesis, structure, and folding of the insulin precursor protein.
    Liu M; Weiss MA; Arunagiri A; Yong J; Rege N; Sun J; Haataja L; Kaufman RJ; Arvan P
    Diabetes Obes Metab; 2018 Sep; 20 Suppl 2(Suppl 2):28-50. PubMed ID: 30230185
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quality Control in the ER: Misfolded Prohormones Get a Checkup.
    Sprunger ML; Jackrel ME
    Mol Cell; 2019 Aug; 75(3):415-416. PubMed ID: 31398319
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinct states of proinsulin misfolding in MIDY.
    Haataja L; Arunagiri A; Hassan A; Regan K; Tsai B; Dhayalan B; Weiss MA; Liu M; Arvan P
    Cell Mol Life Sci; 2021 Aug; 78(16):6017-6031. PubMed ID: 34245311
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.
    Sun J; Cui J; He Q; Chen Z; Arvan P; Liu M
    Mol Aspects Med; 2015 Apr; 42():105-18. PubMed ID: 25579745
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes.
    Balboa D; Saarimäki-Vire J; Borshagovski D; Survila M; Lindholm P; Galli E; Eurola S; Ustinov J; Grym H; Huopio H; Partanen J; Wartiovaara K; Otonkoski T
    Elife; 2018 Nov; 7():. PubMed ID: 30412052
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Misfolded proinsulin impairs processing of precursor of insulin receptor and insulin signaling in β cells.
    Liu S; Li X; Yang J; Zhu R; Fan Z; Xu X; Feng W; Cui J; Sun J; Liu M
    FASEB J; 2019 Oct; 33(10):11338-11348. PubMed ID: 31311313
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proinsulin entry and transit through the endoplasmic reticulum in pancreatic beta cells.
    Liu M; Wright J; Guo H; Xiong Y; Arvan P
    Vitam Horm; 2014; 95():35-62. PubMed ID: 24559913
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Impaired cleavage of preproinsulin signal peptide linked to autosomal-dominant diabetes.
    Liu M; Lara-Lemus R; Shan SO; Wright J; Haataja L; Barbetti F; Guo H; Larkin D; Arvan P
    Diabetes; 2012 Apr; 61(4):828-37. PubMed ID: 22357960
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.