449 related articles for article (PubMed ID: 31179474)
1. Discovery, biological evaluation, structure-activity relationships and mechanism of action of pyrazolo[3,4-b]pyridin-6-one derivatives as a new class of anticancer agents.
Guo Q; Luo Y; Zhai S; Jiang Z; Zhao C; Xu J; Wang L
Org Biomol Chem; 2019 Jun; 17(25):6201-6214. PubMed ID: 31179474
[TBL] [Abstract][Full Text] [Related]
2. Ligand- and structural-based discovery of potential small molecules that target the colchicine site of tubulin for cancer treatment.
Guo Q; Zhang H; Deng Y; Zhai S; Jiang Z; Zhu D; Wang L
Eur J Med Chem; 2020 Jun; 196():112328. PubMed ID: 32320841
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and biological evaluation of 1, 4-dihydro indeno[1,2-c] pyrazole linked oxindole analogues as potential anticancer agents targeting tubulin and inducing p53 dependent apoptosis.
Khan I; Garikapati KR; Shaik AB; Makani VKK; Rahim A; Shareef MA; Reddy VG; Pal-Bhadra M; Kamal A; Kumar CG
Eur J Med Chem; 2018 Jan; 144():104-115. PubMed ID: 29268127
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
Wang YT; Shi TQ; Zhu HL; Liu CH
Bioorg Med Chem; 2019 Feb; 27(3):502-515. PubMed ID: 30606674
[TBL] [Abstract][Full Text] [Related]
6. (E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction.
Wang G; Peng Z; Peng S; Qiu J; Li Y; Lan Y
Bioorg Med Chem Lett; 2018 Nov; 28(20):3350-3355. PubMed ID: 30197030
[TBL] [Abstract][Full Text] [Related]
7. Synthesis, biological evaluation and molecular docking studies of a new series of chalcones containing naphthalene moiety as anticancer agents.
Wang G; Qiu J; Xiao X; Cao A; Zhou F
Bioorg Chem; 2018 Feb; 76():249-257. PubMed ID: 29197743
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
Qin YJ; Li YJ; Jiang AQ; Yang MR; Zhu QZ; Dong H; Zhu HL
Eur J Med Chem; 2015 Apr; 94():447-57. PubMed ID: 25828827
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
Behbahani FS; Tabeshpour J; Mirzaei S; Golmakaniyoon S; Tayarani-Najaran Z; Ghasemi A; Ghodsi R
Arch Pharm (Weinheim); 2019 Jun; 352(6):e1800307. PubMed ID: 31012156
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and bioevaluation of N-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-amines as tubulin polymerization inhibitors with anti-angiogenic effects.
Hao SY; Qi ZY; Wang S; Wang XR; Chen SW
Bioorg Med Chem; 2021 Feb; 31():115985. PubMed ID: 33421913
[TBL] [Abstract][Full Text] [Related]
11. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
Liu YN; Wang JJ; Ji YT; Zhao GD; Tang LQ; Zhang CM; Guo XL; Liu ZP
J Med Chem; 2016 Jun; 59(11):5341-55. PubMed ID: 27172319
[TBL] [Abstract][Full Text] [Related]
12. Discovery of a Series of Acridinones as Mechanism-Based Tubulin Assembly Inhibitors with Anticancer Activity.
Magalhaes LG; Marques FB; da Fonseca MB; Rogério KR; Graebin CS; Andricopulo AD
PLoS One; 2016; 11(8):e0160842. PubMed ID: 27508497
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
Li G; Wang Y; Li L; Ren Y; Deng X; Liu J; Wang W; Luo M; Liu S; Chen J
Eur J Med Chem; 2020 Sep; 202():112519. PubMed ID: 32650183
[TBL] [Abstract][Full Text] [Related]
14. Synthesis of benzo[d]imidazo[2,1-b]thiazole-chalcone conjugates as microtubule targeting and apoptosis inducing agents.
Sultana F; Reddy Bonam S; Reddy VG; Nayak VL; Akunuri R; Rani Routhu S; Alarifi A; Halmuthur MSK; Kamal A
Bioorg Chem; 2018 Feb; 76():1-12. PubMed ID: 29102724
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, Anticancer Activity and Molecular Modeling Studies of Novel Chalcone Derivatives Containing Indole and Naphthalene Moieties as Tubulin Polymerization Inhibitors.
Wang G; Peng Z; Li Y
Chem Pharm Bull (Tokyo); 2019 Jul; 67(7):725-728. PubMed ID: 30982797
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and structure-activity relationships of 5-phenyloxazole-2-carboxylic acid derivatives as novel inhibitors of tubulin polymerization.
Zhang R; Mo H; Ma YY; Zhao DG; Zhang K; Zhang T; Chen X; Zheng X
Bioorg Med Chem Lett; 2021 May; 40():127968. PubMed ID: 33753264
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and biological evaluation of a novel tubulin inhibitor SKLB0565 targeting the colchicine binding site.
Hu X; Li L; Zhang Q; Wang Q; Feng Z; Xu Y; Xia Y; Yu L
Bioorg Chem; 2020 Apr; 97():103695. PubMed ID: 32120073
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of structurally diverse 6-aryl-3-aroyl-indole analogues as inhibitors of tubulin polymerization.
Ren W; Deng Y; Ward JD; Vairin R; Bai R; Wanniarachchi HI; Hamal KB; Tankoano PE; Tamminga CS; Bueno LMA; Hamel E; Mason RP; Trawick ML; Pinney KG
Eur J Med Chem; 2024 Jan; 263():115794. PubMed ID: 37984295
[TBL] [Abstract][Full Text] [Related]
19. Anticancer activity of gallic acid template-based benzylidene indanone derivative as microtubule destabilizer.
Singh A; Fatima K; Srivastava A; Khwaja S; Priya D; Singh A; Mahajan G; Alam S; Saxena AK; Mondhe DM; Luqman S; Chanda D; Khan F; Negi AS
Chem Biol Drug Des; 2016 Nov; 88(5):625-634. PubMed ID: 27495835
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, biological evaluation and molecular docking studies of new chalcone derivatives containing diaryl ether moiety as potential anticancer agents and tubulin polymerization inhibitors.
Wang G; Liu W; Gong Z; Huang Y; Li Y; Peng Z
Bioorg Chem; 2020 Jan; 95():103565. PubMed ID: 31927336
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
