These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 31180118)

  • 1. P-Glycoprotein-Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium.
    Arnold SLM; Choi R; Hulverson MA; Whitman GR; Mccloskey MC; Dorr CS; Vidadala RSR; Khatod M; Morada M; Barrett LK; Maly DJ; Yarlett N; Van Voorhis WC
    J Infect Dis; 2019 Aug; 220(7):1188-1198. PubMed ID: 31180118
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Therapeutic Efficacy of Bumped Kinase Inhibitor 1369 in a Pig Model of Acute Diarrhea Caused by Cryptosporidium hominis.
    Lee S; Ginese M; Beamer G; Danz HR; Girouard DJ; Chapman-Bonofiglio SP; Lee M; Hulverson MA; Choi R; Whitman GR; Ojo KK; Arnold SLM; Van Voorhis WC; Tzipori S
    Antimicrob Agents Chemother; 2018 Jul; 62(7):. PubMed ID: 29661877
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection.
    Arnold SLM; Choi R; Hulverson MA; Schaefer DA; Vinayak S; Vidadala RSR; McCloskey MC; Whitman GR; Huang W; Barrett LK; Ojo KK; Fan E; Maly DJ; Riggs MW; Striepen B; Van Voorhis WC
    J Infect Dis; 2017 Jul; 216(1):55-63. PubMed ID: 28541457
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis.
    Manjunatha UH; Vinayak S; Zambriski JA; Chao AT; Sy T; Noble CG; Bonamy GMC; Kondreddi RR; Zou B; Gedeck P; Brooks CF; Herbert GT; Sateriale A; Tandel J; Noh S; Lakshminarayana SB; Lim SH; Goodman LB; Bodenreider C; Feng G; Zhang L; Blasco F; Wagner J; Leong FJ; Striepen B; Diagana TT
    Nature; 2017 Jun; 546(7658):376-380. PubMed ID: 28562588
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Predicting P-glycoprotein effects on oral absorption: correlation of transport in Caco-2 with drug pharmacokinetics in wild-type and mdr1a(-/-) mice in vivo.
    Collett A; Tanianis-Hughes J; Hallifax D; Warhurst G
    Pharm Res; 2004 May; 21(5):819-26. PubMed ID: 15180340
    [TBL] [Abstract][Full Text] [Related]  

  • 6. New Tools for Cryptosporidium Lead to New Hope for Cryptosporidiosis.
    Ward HD
    Trends Parasitol; 2017 Sep; 33(9):662-664. PubMed ID: 28750950
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Efficacy of chitosan, a natural polysaccharide, against Cryptosporidium parvum in vitro and in vivo in neonatal mice.
    Mammeri M; Chevillot A; Thomas M; Polack B; Julien C; Marden JP; Auclair E; Vallée I; Adjou KT
    Exp Parasitol; 2018 Nov; 194():1-8. PubMed ID: 30237052
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of 5-Aminopyrazole-4-carboxamide-based Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy.
    Huang W; Hulverson MA; Choi R; Arnold SLM; Zhang Z; McCloskey MC; Whitman GR; Hackman RC; Rivas KL; Barrett LK; Ojo KK; Van Voorhis WC; Fan E
    J Med Chem; 2019 Mar; 62(6):3135-3146. PubMed ID: 30830766
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cryptosporidiosis Drug Discovery: Opportunities and Challenges.
    Manjunatha UH; Chao AT; Leong FJ; Diagana TT
    ACS Infect Dis; 2016 Aug; 2(8):530-7. PubMed ID: 27626293
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.
    Yu XY; Lin SG; Zhou ZW; Chen X; Liang J; Liu PQ; Duan W; Chowbay B; Wen JY; Li CG; Zhou SF
    Curr Drug Metab; 2007 May; 8(4):325-40. PubMed ID: 17504222
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analysis of intestinal epithelial cell responses to Cryptosporidium highlights the temporal effects of IFN-γ on parasite restriction.
    Pardy RD; Walzer KA; Wallbank BA; Byerly JH; O'Dea KM; Cohn IS; Haskins BE; Roncaioli JL; Smith EJ; Buenconsejo GY; Striepen B; Hunter CA
    PLoS Pathog; 2024 May; 20(5):e1011820. PubMed ID: 38718306
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Zinc finger nuclease-mediated gene knockout results in loss of transport activity for P-glycoprotein, BCRP, and MRP2 in Caco-2 cells.
    Sampson KE; Brinker A; Pratt J; Venkatraman N; Xiao Y; Blasberg J; Steiner T; Bourner M; Thompson DC
    Drug Metab Dispos; 2015 Feb; 43(2):199-207. PubMed ID: 25388687
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Lin X; Skolnik S; Chen X; Wang J
    Drug Metab Dispos; 2011 Feb; 39(2):265-74. PubMed ID: 21051535
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacokinetics and Pharmacodynamics of Clofazimine for Treatment of Cryptosporidiosis.
    Zhang CX; Love MS; McNamara CW; Chi V; Woods AK; Joseph S; Schaefer DA; Betzer DP; Riggs MW; Iroh Tam PY; Van Voorhis WC; Arnold SLM
    Antimicrob Agents Chemother; 2022 Jan; 66(1):e0156021. PubMed ID: 34748385
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of P-glycoprotein-mediated secretion in absorptive drug permeability: An approach using passive membrane permeability and affinity to P-glycoprotein.
    Döppenschmitt S; Spahn-Langguth H; Regårdh CG; Langguth P
    J Pharm Sci; 1999 Oct; 88(10):1067-72. PubMed ID: 10514357
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phenotypic screening techniques for
    Love MS; McNamara CW
    Expert Opin Drug Discov; 2021 Jan; 16(1):59-74. PubMed ID: 32892652
    [No Abstract]   [Full Text] [Related]  

  • 17. P-glycoprotein and breast cancer resistance protein affect disposition of tandutinib, a tyrosine kinase inhibitor.
    Yang JJ; Milton MN; Yu S; Liao M; Liu N; Wu JT; Gan L; Balani SK; Lee FW; Prakash S; Xia CQ
    Drug Metab Lett; 2010 Dec; 4(4):201-12. PubMed ID: 20670210
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Mathematical simulation to explain the coordinated functions of efflux and metabolism limiting the transport of anti-HIV agents across Caco-2 cells.
    Patel J; Hussain A; Pal D; Mitra AK
    Am J Ther; 2004; 11(2):114-23. PubMed ID: 14999363
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis.
    Love MS; Beasley FC; Jumani RS; Wright TM; Chatterjee AK; Huston CD; Schultz PG; McNamara CW
    PLoS Negl Trop Dis; 2017 Feb; 11(2):e0005373. PubMed ID: 28158186
    [TBL] [Abstract][Full Text] [Related]  

  • 20. P-glycoprotein (ABCB1) is involved in vitamin K efflux.
    Margier M; Le May C; Antoine T; Halimi C; Nowicki M; Lespine A; Reboul E
    Food Chem; 2021 May; 343():128510. PubMed ID: 33172753
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.