These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 31180641)

  • 61. Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation.
    Tambini MD; Norris KA; D'Adamio L
    Elife; 2020 Feb; 9():. PubMed ID: 32022689
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Familial Alzheimer's disease Osaka mutant (ΔE22) β-barrels suggest an explanation for the different Aβ1-40/42 preferred conformational states observed by experiment.
    Jang H; Arce FT; Ramachandran S; Kagan BL; Lal R; Nussinov R
    J Phys Chem B; 2013 Oct; 117(39):11518-29. PubMed ID: 24000923
    [TBL] [Abstract][Full Text] [Related]  

  • 63. beta-site specific intrabodies to decrease and prevent generation of Alzheimer's Abeta peptide.
    Paganetti P; Calanca V; Galli C; Stefani M; Molinari M
    J Cell Biol; 2005 Mar; 168(6):863-8. PubMed ID: 15767460
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta.
    Lopez Sanchez MIG; Waugh HS; Tsatsanis A; Wong BX; Crowston JG; Duce JA; Trounce IA
    Sci Rep; 2017 Aug; 7(1):9835. PubMed ID: 28852095
    [TBL] [Abstract][Full Text] [Related]  

  • 65. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein.
    De Strooper B; Saftig P; Craessaerts K; Vanderstichele H; Guhde G; Annaert W; Von Figura K; Van Leuven F
    Nature; 1998 Jan; 391(6665):387-90. PubMed ID: 9450754
    [TBL] [Abstract][Full Text] [Related]  

  • 66. What is the role of amyloid precursor protein dimerization?
    Khalifa NB; Van Hees J; Tasiaux B; Huysseune S; Smith SO; Constantinescu SN; Octave JN; Kienlen-Campard P
    Cell Adh Migr; 2010; 4(2):268-72. PubMed ID: 20400860
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Evaluation of the Expression of Amyloid Precursor Protein and the Ratio of Secreted Amyloid Beta 42 to Amyloid Beta 40 in SH-SY5Y Cells Stably Transfected with Wild-Type, Single-Mutant and Double-Mutant Forms of the APP Gene for the Study of Alzheimer's Disease Pathology.
    Pahrudin Arrozi A; Shukri SNS; Wan Ngah WZ; Mohd Yusof YA; Ahmad Damanhuri MH; Makpol S
    Appl Biochem Biotechnol; 2017 Nov; 183(3):853-866. PubMed ID: 28417423
    [TBL] [Abstract][Full Text] [Related]  

  • 68. The Protective A673T Mutation of Amyloid Precursor Protein (APP) in Alzheimer's Disease.
    Xia Q; Yang X; Shi J; Liu Z; Peng Y; Wang W; Li B; Zhao Y; Xiao J; Huang L; Wang D; Gao X
    Mol Neurobiol; 2021 Aug; 58(8):4038-4050. PubMed ID: 33914267
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Evidence from solid-state NMR for nonhelical conformations in the transmembrane domain of the amyloid precursor protein.
    Lu JX; Yau WM; Tycko R
    Biophys J; 2011 Feb; 100(3):711-719. PubMed ID: 21281586
    [TBL] [Abstract][Full Text] [Related]  

  • 70. An alternative secretase cleavage produces soluble Alzheimer amyloid precursor protein containing a potentially amyloidogenic sequence.
    Anderson JP; Chen Y; Kim KS; Robakis NK
    J Neurochem; 1992 Dec; 59(6):2328-31. PubMed ID: 1431910
    [TBL] [Abstract][Full Text] [Related]  

  • 71. An overview of APP processing enzymes and products.
    Chow VW; Mattson MP; Wong PC; Gleichmann M
    Neuromolecular Med; 2010 Mar; 12(1):1-12. PubMed ID: 20232515
    [TBL] [Abstract][Full Text] [Related]  

  • 72. Pharmacological characterization of the novel γ-secretase modulator AS2715348, a potential therapy for Alzheimer's disease, in rodents and nonhuman primates.
    Mitani Y; Akashiba H; Saita K; Yarimizu J; Uchino H; Okabe M; Asai M; Yamasaki S; Nozawa T; Ishikawa N; Shitaka Y; Ni K; Matsuoka N
    Neuropharmacology; 2014 Apr; 79():412-9. PubMed ID: 24373902
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Alzheimer disease: amyloidogenesis, the presenilins and animal models.
    Newman M; Musgrave IF; Lardelli M
    Biochim Biophys Acta; 2007 Mar; 1772(3):285-97. PubMed ID: 17208417
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Familial Alzheimer's disease mutations in presenilin 1 do not alter levels of the secreted amyloid-beta protein precursor generated by beta-secretase cleavage.
    Zhang C; Browne A; Kim DY; Tanzi RE
    Curr Alzheimer Res; 2010 Feb; 7(1):21-6. PubMed ID: 20205669
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Novel mutations introduced at the beta-site of amyloid beta protein precursor enhance the production of amyloid beta peptide by BACE1 in vitro and in cells.
    Shi XP; Tugusheva K; Bruce JE; Lucka A; Chen-Dodson E; Hu B; Wu GX; Price E; Register RB; Lineberger J; Miller R; Tang MJ; Espeseth A; Kahana J; Wolfe A; Crouthamel MC; Sankaranarayanan S; Simon A; Chen L; Lai MT; Pietrak B; DiMuzio J; Li Y; Xu M; Huang Q; Garsky V; Sardana MK; Hazuda DJ
    J Alzheimers Dis; 2005 Apr; 7(2):139-48; discussion 173-80. PubMed ID: 15851852
    [TBL] [Abstract][Full Text] [Related]  

  • 76. A mutation in APP protects against Alzheimer's disease and age-related cognitive decline.
    Jonsson T; Atwal JK; Steinberg S; Snaedal J; Jonsson PV; Bjornsson S; Stefansson H; Sulem P; Gudbjartsson D; Maloney J; Hoyte K; Gustafson A; Liu Y; Lu Y; Bhangale T; Graham RR; Huttenlocher J; Bjornsdottir G; Andreassen OA; Jönsson EG; Palotie A; Behrens TW; Magnusson OT; Kong A; Thorsteinsdottir U; Watts RJ; Stefansson K
    Nature; 2012 Aug; 488(7409):96-9. PubMed ID: 22801501
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.
    Weidemann A; Paliga K; Dürrwang U; Reinhard FB; Schuckert O; Evin G; Masters CL
    J Biol Chem; 1999 Feb; 274(9):5823-9. PubMed ID: 10026204
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Novel amyloid precursor protein mutation, Val669Leu ("Seoul APP"), in a Korean patient with early-onset Alzheimer's disease.
    Bagyinszky E; Kang MJ; Van Giau V; Shim K; Pyun JM; Suh J; An SSA; Kim S
    Neurobiol Aging; 2019 Dec; 84():236.e1-236.e7. PubMed ID: 31623876
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Structural Studies Providing Insights into Production and Conformational Behavior of Amyloid-β Peptide Associated with Alzheimer's Disease Development.
    Urban AS; Pavlov KV; Kamynina AV; Okhrimenko IS; Arseniev AS; Bocharov EV
    Molecules; 2021 May; 26(10):. PubMed ID: 34068293
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Structural and dynamic study of the transmembrane domain of the amyloid precursor protein.
    Nadezhdin KD; Bocharova OV; Bocharov EV; Arseniev AS
    Acta Naturae; 2011 Jan; 3(1):69-76. PubMed ID: 22649674
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.