These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

323 related articles for article (PubMed ID: 31184302)

  • 1. Proinsulin misfolding is an early event in the progression to type 2 diabetes.
    Arunagiri A; Haataja L; Pottekat A; Pamenan F; Kim S; Zeltser LM; Paton AW; Paton JC; Tsai B; Itkin-Ansari P; Kaufman RJ; Liu M; Arvan P
    Elife; 2019 Jun; 8():. PubMed ID: 31184302
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disulfide Mispairing During Proinsulin Folding in the Endoplasmic Reticulum.
    Haataja L; Manickam N; Soliman A; Tsai B; Liu M; Arvan P
    Diabetes; 2016 Apr; 65(4):1050-60. PubMed ID: 26822090
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Distinct states of proinsulin misfolding in MIDY.
    Haataja L; Arunagiri A; Hassan A; Regan K; Tsai B; Dhayalan B; Weiss MA; Liu M; Arvan P
    Cell Mol Life Sci; 2021 Aug; 78(16):6017-6031. PubMed ID: 34245311
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.
    Sun J; Cui J; He Q; Chen Z; Arvan P; Liu M
    Mol Aspects Med; 2015 Apr; 42():105-18. PubMed ID: 25579745
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.
    Arunagiri A; Haataja L; Cunningham CN; Shrestha N; Tsai B; Qi L; Liu M; Arvan P
    Ann N Y Acad Sci; 2018 Apr; 1418(1):5-19. PubMed ID: 29377149
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
    Arunagiri A; Alam M; Haataja L; Draz H; Alasad B; Samy P; Sadique N; Tong Y; Cai Y; Shakeri H; Fantuzzi F; Ibrahim H; Jang I; Sidarala V; Soleimanpour SA; Satin LS; Otonkoski T; Cnop M; Itkin-Ansari P; Kaufman RJ; Liu M; Arvan P
    Protein Sci; 2024 Apr; 33(4):e4949. PubMed ID: 38511500
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biological behaviors of mutant proinsulin contribute to the phenotypic spectrum of diabetes associated with insulin gene mutations.
    Wang H; Saint-Martin C; Xu J; Ding L; Wang R; Feng W; Liu M; Shu H; Fan Z; Haataja L; Arvan P; Bellanné-Chantelot C; Cui J; Huang Y
    Mol Cell Endocrinol; 2020 Dec; 518():111025. PubMed ID: 32916194
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proinsulin disulfide maturation and misfolding in the endoplasmic reticulum.
    Liu M; Li Y; Cavener D; Arvan P
    J Biol Chem; 2005 Apr; 280(14):13209-12. PubMed ID: 15705595
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.
    Jang I; Pottekat A; Poothong J; Yong J; Lagunas-Acosta J; Charbono A; Chen Z; Scheuner DL; Liu M; Itkin-Ansari P; Arvan P; Kaufman RJ
    Elife; 2019 Jun; 8():. PubMed ID: 31184304
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress.
    Wright J; Birk J; Haataja L; Liu M; Ramming T; Weiss MA; Appenzeller-Herzog C; Arvan P
    J Biol Chem; 2013 Oct; 288(43):31010-8. PubMed ID: 24022479
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biosynthesis, structure, and folding of the insulin precursor protein.
    Liu M; Weiss MA; Arunagiri A; Yong J; Rege N; Sun J; Haataja L; Kaufman RJ; Arvan P
    Diabetes Obes Metab; 2018 Sep; 20 Suppl 2(Suppl 2):28-50. PubMed ID: 30230185
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The inducible β5i proteasome subunit contributes to proinsulin degradation in GRP94-deficient β-cells and is overexpressed in type 2 diabetes pancreatic islets.
    Khilji MS; Bresson SE; Verstappen D; Pihl C; Andersen PAK; Agergaard JB; Dahlby T; Bryde TH; Klindt K; Nielsen CK; Walentinsson A; Zivkovic D; Bousquet MP; Tyrberg B; Richardson SJ; Morgan NG; Mandrup-Poulsen T; Marzec MT
    Am J Physiol Endocrinol Metab; 2020 Jun; 318(6):E892-E900. PubMed ID: 32255680
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Defective endoplasmic reticulum export causes proinsulin misfolding in pancreatic β cells.
    Zhu R; Li X; Xu J; Barrabi C; Kekulandara D; Woods J; Chen X; Liu M
    Mol Cell Endocrinol; 2019 Aug; 493():110470. PubMed ID: 31158417
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of deletion and shift of the A20-B19 disulfide bond on the structure, activity, and refolding of proinsulin.
    Wang ZH; Liu Y; Ji JG; Tang JG
    J Biochem; 2004 Jan; 135(1):25-31. PubMed ID: 14999006
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proinsulin entry and transit through the endoplasmic reticulum in pancreatic beta cells.
    Liu M; Wright J; Guo H; Xiong Y; Arvan P
    Vitam Horm; 2014; 95():35-62. PubMed ID: 24559913
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Control of precursor maturation and disposal is an early regulative mechanism in the normal insulin production of pancreatic β-cells.
    Wang J; Chen Y; Yuan Q; Tang W; Zhang X; Osei K
    PLoS One; 2011 Apr; 6(4):e19446. PubMed ID: 21559376
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse.
    Izumi T; Yokota-Hashimoto H; Zhao S; Wang J; Halban PA; Takeuchi T
    Diabetes; 2003 Feb; 52(2):409-16. PubMed ID: 12540615
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Intracellular transport of proinsulin in pancreatic beta-cells. Structural maturation probed by disulfide accessibility.
    Huang XF; Arvan P
    J Biol Chem; 1995 Sep; 270(35):20417-23. PubMed ID: 7657617
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells.
    Iida H; Kono T; Lee CC; Krishnan P; Arvin MC; Weaver SA; Jarvela TS; Branco RCS; McLaughlin MR; Bone RN; Tong X; Arvan P; Lindberg I; Evans-Molina C
    Diabetologia; 2023 Nov; 66(11):2042-2061. PubMed ID: 37537395
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Diabetes-Associated Mutations in Proinsulin Provide a "Molecular Rheostat" of Nascent Foldability.
    Dhayalan B; Weiss MA
    Curr Diab Rep; 2022 Feb; 22(2):85-94. PubMed ID: 35119630
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.