232 related articles for article (PubMed ID: 31191531)
1. Disruption of Telomere Integrity and DNA Repair Machineries by KML001 Induces T Cell Senescence, Apoptosis, and Cellular Dysfunctions.
Cao D; Zhao J; Nguyan LN; Nguyen LNT; Khanal S; Dang X; Schank M; Chand Thakuri BK; Wu XY; Morrison ZD; El Gazzar M; Zou Y; Ning S; Wang L; Moorman JP; Yao ZQ
Front Immunol; 2019; 10():1152. PubMed ID: 31191531
[TBL] [Abstract][Full Text] [Related]
2. Telomeric injury by KML001 in human T cells induces mitochondrial dysfunction through the p53-PGC-1α pathway.
Schank M; Zhao J; Wang L; Li Z; Cao D; Nguyen LN; Dang X; Khanal S; Nguyen LNT; Thakuri BKC; Ogbu SC; Lu Z; Zhang J; Wu XY; Morrison ZD; El Gazzar M; Ning S; Moorman JP; Yao ZQ
Cell Death Dis; 2020 Dec; 11(12):1030. PubMed ID: 33268822
[TBL] [Abstract][Full Text] [Related]
3. KML001 cytotoxic activity is associated with its binding to telomeric sequences and telomere erosion in prostate cancer cells.
Phatak P; Dai F; Butler M; Nandakumar MP; Gutierrez PL; Edelman MJ; Hendriks H; Burger AM
Clin Cancer Res; 2008 Jul; 14(14):4593-602. PubMed ID: 18628474
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of TRF2 accelerates telomere attrition and DNA damage in naïve CD4 T cells during HCV infection.
Nguyen LN; Zhao J; Cao D; Dang X; Wang L; Lian J; Zhang Y; Jia Z; Wu XY; Morrison Z; Xie Q; Ji Y; Zhang Z; El Gazzar M; Ning S; Moorman JP; Yao ZQ
Cell Death Dis; 2018 Sep; 9(9):900. PubMed ID: 30185784
[TBL] [Abstract][Full Text] [Related]
5. Telomere and ATM Dynamics in CD4 T-Cell Depletion in Active and Virus-Suppressed HIV Infections.
Khanal S; Tang Q; Cao D; Zhao J; Nguyen LN; Oyedeji OS; Dang X; Nguyen LNT; Schank M; Thakuri BKC; Ogbu C; Morrison ZD; Wu XY; Zhang Z; He Q; El Gazzar M; Li Z; Ning S; Wang L; Moorman JP; Yao ZQ
J Virol; 2020 Oct; 94(22):. PubMed ID: 32907975
[TBL] [Abstract][Full Text] [Related]
6. ATM Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy.
Zhao J; Nguyen LNT; Nguyen LN; Dang X; Cao D; Khanal S; Schank M; Thakuri BKC; Ogbu SC; Morrison ZD; Wu XY; Li Z; Zou Y; El Gazzar M; Ning S; Wang L; Moorman JP; Yao ZQ
Front Immunol; 2019; 10():2531. PubMed ID: 31781094
[TBL] [Abstract][Full Text] [Related]
7. Anti-tumoral effect of arsenic compound, sodium metaarsenite (KML001), in non-Hodgkin's lymphoma: an in vitro and in vivo study.
Yoon JS; Hwang DW; Kim ES; Kim JS; Kim S; Chung HJ; Lee SK; Yi JH; Uhm J; Won YW; Park BB; Choi JH; Lee YY
Invest New Drugs; 2016 Feb; 34(1):1-14. PubMed ID: 26581399
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of topoisomerase IIA (Top2α) induces telomeric DNA damage and T cell dysfunction during chronic viral infection.
Dang X; Ogbu SC; Zhao J; Nguyen LNT; Cao D; Nguyen LN; Khanal S; Schank M; Thakuri BKC; Wu XY; Morrison ZD; Zhang J; Li Z; El Gazzar M; Ning S; Wang L; Wang Z; Moorman JP; Yao ZQ
Cell Death Dis; 2020 Mar; 11(3):196. PubMed ID: 32193368
[TBL] [Abstract][Full Text] [Related]
9. KML001, a telomere-targeting drug, sensitizes glioblastoma cells to temozolomide chemotherapy and radiotherapy through DNA damage and apoptosis.
Woo SR; Ham Y; Kang W; Yang H; Kim S; Jin J; Joo KM; Nam DH
Biomed Res Int; 2014; 2014():747415. PubMed ID: 25295271
[TBL] [Abstract][Full Text] [Related]
10. Immune Activation Induces Telomeric DNA Damage and Promotes Short-Lived Effector T Cell Differentiation in Chronic HCV Infection.
Nguyen LN; Nguyen LNT; Zhao J; Schank M; Dang X; Cao D; Khanal S; Thakuri BKC; Zhang J; Lu Z; Wu XY; El Gazzar M; Ning S; Wang L; Moorman JP; Yao ZQ
Hepatology; 2021 Nov; 74(5):2380-2394. PubMed ID: 34110660
[TBL] [Abstract][Full Text] [Related]
11. KML001 Induces Apoptosis and Autophagic Cell Death in Prostate Cancer Cells via Oxidative Stress Pathway.
You D; Kim Y; Jang MJ; Lee C; Jeong IG; Cho YM; Hwang JJ; Hong JH; Ahn H; Kim CS
PLoS One; 2015; 10(9):e0137589. PubMed ID: 26352139
[TBL] [Abstract][Full Text] [Related]
12. BIBR1532, a Selective Telomerase Inhibitor, Enhances Radiosensitivity of Non-Small Cell Lung Cancer Through Increasing Telomere Dysfunction and ATM/CHK1 Inhibition.
Ding X; Cheng J; Pang Q; Wei X; Zhang X; Wang P; Yuan Z; Qian D
Int J Radiat Oncol Biol Phys; 2019 Nov; 105(4):861-874. PubMed ID: 31419512
[TBL] [Abstract][Full Text] [Related]
13. Antitumoral effect of arsenic compound, sodium metaarsenite (KML001), on multiple myeloma cells.
Kim SJ; Kim ES; Kim S; Uhm J; Won YW; Park BB; Choi JH; Lee YY
Int J Oncol; 2017 Dec; 51(6):1739-1746. PubMed ID: 29039521
[TBL] [Abstract][Full Text] [Related]
14. TRF2 inhibition rather than telomerase disruption drives CD4T cell dysfunction during chronic viral infection.
Nguyen LNT; Nguyen LN; Zhao J; Schank M; Dang X; Cao D; Khanal S; Wu XY; Zhang Y; Zhang J; Ning S; Wang L; El Gazzar M; Moorman JP; Yao ZQ
J Cell Sci; 2022 Jul; 135(13):. PubMed ID: 35660868
[TBL] [Abstract][Full Text] [Related]
15. G-quadruplex ligands targeting telomeres do not inhibit HIV promoter activity and cooperate with latency reversing agents in killing latently infected cells.
Piekna-Przybylska D; Bambara RA; Maggirwar SB; Dewhurst S
Cell Cycle; 2020 Sep; 19(18):2298-2313. PubMed ID: 32807015
[TBL] [Abstract][Full Text] [Related]
16. KML001 displays vascular disrupting properties and irinotecan combined antitumor activities in a murine tumor model.
Moon CH; Lee SJ; Lee HY; Lee JC; Cha H; Cho WJ; Park JW; Park HJ; Seo J; Lee YH; Song HT; Min YJ
PLoS One; 2013; 8(1):e53900. PubMed ID: 23326531
[TBL] [Abstract][Full Text] [Related]
17. Topological DNA damage, telomere attrition and T cell senescence during chronic viral infections.
Ji Y; Dang X; Nguyen LNT; Nguyen LN; Zhao J; Cao D; Khanal S; Schank M; Wu XY; Morrison ZD; Zou Y; El Gazzar M; Ning S; Wang L; Moorman JP; Yao ZQ
Immun Ageing; 2019; 16():12. PubMed ID: 31285747
[TBL] [Abstract][Full Text] [Related]
18. Anti-Tumor Effects of Sodium Meta-Arsenite in Glioblastoma Cells with Higher Akt Activities.
Lee EJ; Sung JY; Koo KH; Park JB; Kim DH; Shim J; Lee CH; Park J; Kim YN
Int J Mol Sci; 2020 Nov; 21(23):. PubMed ID: 33256086
[TBL] [Abstract][Full Text] [Related]
19. KML001 and doxercalciferol induce synergistic antileukemic effect in acute lymphoid leukemia cells.
Liu Y; Shin DY; Oh S; Kim S; Koh Y; Kim I
Oncol Rep; 2017 Jul; 38(1):481-487. PubMed ID: 28586017
[TBL] [Abstract][Full Text] [Related]
20. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
Denchi EL; de Lange T
Nature; 2007 Aug; 448(7157):1068-71. PubMed ID: 17687332
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]