127 related articles for article (PubMed ID: 31195171)
1. Evaluating the effects of fluorine on biological properties and metabolic stability of some antitubulin 3-substituted 7-phenyl-pyrroloquinolinones.
Bortolozzi R; Carta D; Prà MD; Antoniazzi G; Mattiuzzo E; Sturlese M; Di Paolo V; Calderan L; Moro S; Hamel E; Quintieri L; Ronca R; Viola G; Ferlin MG
Eur J Med Chem; 2019 Sep; 178():297-314. PubMed ID: 31195171
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents.
Carta D; Bortolozzi R; Sturlese M; Salmaso V; Hamel E; Basso G; Calderan L; Quintieri L; Moro S; Viola G; Ferlin MG
Eur J Med Chem; 2017 Feb; 127():643-660. PubMed ID: 27823884
[TBL] [Abstract][Full Text] [Related]
3. Targeting tubulin polymerization by novel 7-aryl-pyrroloquinolinones: Synthesis, biological activity and SARs.
Bortolozzi R; Mattiuzzo E; Dal Pra M; Sturlese M; Moro S; Hamel E; Carta D; Viola G; Ferlin MG
Eur J Med Chem; 2018 Jan; 143():244-258. PubMed ID: 29197729
[TBL] [Abstract][Full Text] [Related]
4. A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation.
Naret T; Bignon J; Bernadat G; Benchekroun M; Levaique H; Lenoir C; Dubois J; Pruvost A; Saller F; Borgel D; Manoury B; Leblais V; Darrigrand R; Apcher S; Brion JD; Schmitt E; Leroux FR; Alami M; Hamze A
Eur J Med Chem; 2018 Jan; 143():473-490. PubMed ID: 29202409
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
Wang G; Li C; He L; Lei K; Wang F; Pu Y; Yang Z; Cao D; Ma L; Chen J; Sang Y; Liang X; Xiang M; Peng A; Wei Y; Chen L
Bioorg Med Chem; 2014 Apr; 22(7):2060-79. PubMed ID: 24629450
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
Penthala NR; Zong H; Ketkar A; Madadi NR; Janganati V; Eoff RL; Guzman ML; Crooks PA
Eur J Med Chem; 2015 Mar; 92():212-20. PubMed ID: 25557492
[TBL] [Abstract][Full Text] [Related]
7. (E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction.
Wang G; Peng Z; Peng S; Qiu J; Li Y; Lan Y
Bioorg Med Chem Lett; 2018 Nov; 28(20):3350-3355. PubMed ID: 30197030
[TBL] [Abstract][Full Text] [Related]
8. Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors.
Řehulka J; Vychodilová K; Krejčí P; Gurská S; Hradil P; Hajdúch M; Džubák P; Hlaváč J
Eur J Med Chem; 2020 Apr; 192():112176. PubMed ID: 32120327
[TBL] [Abstract][Full Text] [Related]
9. Anticancer properties of indole derivatives as IsoCombretastatin A-4 analogues.
Pecnard S; Hamze A; Bignon J; Prost B; Deroussent A; Gallego-Yerga L; Peláez R; Paik JY; Diederich M; Alami M; Provot O
Eur J Med Chem; 2021 Nov; 223():113656. PubMed ID: 34171660
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological evaluation of 1,2,3-triazole linked aminocombretastatin conjugates as mitochondrial mediated apoptosis inducers.
Kamal A; Shaik B; Nayak VL; Nagaraju B; Kapure JS; Shaheer Malik M; Shaik TB; Prasad B
Bioorg Med Chem; 2014 Oct; 22(19):5155-67. PubMed ID: 25192811
[TBL] [Abstract][Full Text] [Related]
11. Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.
Romagnoli R; Preti D; Hamel E; Bortolozzi R; Viola G; Brancale A; Ferla S; Morciano G; Pinton P
Bioorg Chem; 2021 Jul; 112():104919. PubMed ID: 33957538
[TBL] [Abstract][Full Text] [Related]
12. Sulfamic acid promoted one-pot synthesis of phenanthrene fused-dihydrodibenzo-quinolinones: Anticancer activity, tubulin polymerization inhibition and apoptosis inducing studies.
Kumar NP; Thatikonda S; Tokala R; Kumari SS; Lakshmi UJ; Godugu C; Shankaraiah N; Kamal A
Bioorg Med Chem; 2018 May; 26(8):1996-2008. PubMed ID: 29525336
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
Liu Y; Wei D; Zhao Y; Cheng W; Lu Y; Ma Y; Li X; Han C; Wei Y; Cao H; Zhao C
Bioorg Med Chem; 2012 Nov; 20(21):6285-95. PubMed ID: 23022053
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
Romagnoli R; Baraldi PG; Pavani MG; Tabrizi MA; Preti D; Fruttarolo F; Piccagli L; Jung MK; Hamel E; Borgatti M; Gambari R
J Med Chem; 2006 Jun; 49(13):3906-15. PubMed ID: 16789746
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
[TBL] [Abstract][Full Text] [Related]
16. Antitumor Agents. 211. Fluorinated 2-phenyl-4-quinolone derivatives as antimitotic antitumor agents.
Xia Y; Yang ZY; Xia P; Hackl T; Hamel E; Mauger A; Wu JH; Lee KH
J Med Chem; 2001 Nov; 44(23):3932-6. PubMed ID: 11689079
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and bioevaluation of antitubulin agents carrying diaryl-5,5-fused-heterocycle scaffold.
Xu Q; Sun M; Bai Z; Wang Y; Wu Y; Tian H; Zuo D; Guan Q; Bao K; Wu Y; Zhang W
Eur J Med Chem; 2017 Oct; 139():242-249. PubMed ID: 28802124
[TBL] [Abstract][Full Text] [Related]
18. YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo.
Cai D; Qiu Z; Yao W; Liu Y; Huang H; Liao S; Luo Q; Xie L; Lin Z
Cancer Chemother Pharmacol; 2016 Jun; 77(6):1217-29. PubMed ID: 27107592
[TBL] [Abstract][Full Text] [Related]
19. Synthesis, biological evaluation, and molecular docking studies of 2,6-dinitro-4-(trifluoromethyl)phenoxysalicylaldoxime derivatives as novel antitubulin agents.
Zhao TT; Lu X; Yang XH; Wang LM; Li X; Wang ZC; Gong HB; Zhu HL
Bioorg Med Chem; 2012 May; 20(10):3233-41. PubMed ID: 22512906
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors.
Kazan F; Yagci ZB; Bai R; Ozkirimli E; Hamel E; Ozkirimli S
Comput Biol Chem; 2019 Jun; 80():512-523. PubMed ID: 31185422
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
