These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

342 related articles for article (PubMed ID: 31197246)

  • 1. Discovery and characterization of natural products as novel indoleamine 2,3-dioxygenase 1 inhibitors through high-throughput screening.
    Guo W; Yao S; Sun P; Yang TB; Tang CP; Zheng MY; Ye Y; Meng LH
    Acta Pharmacol Sin; 2020 Mar; 41(3):423-431. PubMed ID: 31197246
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery and Characterisation of Dual Inhibitors of Tryptophan 2,3-Dioxygenase (TDO2) and Indoleamine 2,3-Dioxygenase 1 (IDO1) Using Virtual Screening.
    Sari S; Tomek P; Leung E; Reynisson J
    Molecules; 2019 Nov; 24(23):. PubMed ID: 31795096
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation and comparison of the commonly used bioassays of human indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO).
    Zhang S; Guo L; Yang D; Xing Z; Li W; Kuang C; Yang Q
    Bioorg Chem; 2020 Nov; 104():104348. PubMed ID: 33142415
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of novel tryptanthrin derivatives as dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase.
    Li Y; Zhang S; Wang R; Cui M; Liu W; Yang Q; Kuang C
    Bioorg Med Chem Lett; 2020 Jun; 30(11):127159. PubMed ID: 32247733
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1).
    Fung SP; Wang H; Tomek P; Squire CJ; Flanagan JU; Palmer BD; Bridewell DJ; Tijono SM; Jamie JF; Ching LM
    Bioorg Med Chem; 2013 Dec; 21(24):7595-603. PubMed ID: 24262887
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of indole-2-carboxylic acid derivatives as IDO1/TDO dual inhibitors.
    Cui G; Lai F; Wang X; Chen X; Xu B
    Eur J Med Chem; 2020 Feb; 188():111985. PubMed ID: 31881488
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Novel High Throughput Virtual Screening Protocol to Discover New Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.
    Xu H; Song Y; Yang Q
    Chem Pharm Bull (Tokyo); 2017; 65(8):714-717. PubMed ID: 28768924
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Parallel discovery of selective and dual inhibitors of tryptophan dioxygenases IDO1 and TDO2 with a newly-modified enzymatic assay.
    Capochiani de Iudicibus R; Tomek P; Palmer BD; Tijono SM; Flanagan JU; Ching LM
    Bioorg Med Chem; 2021 Jun; 39():116160. PubMed ID: 33901770
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery and evaluation of inhibitors to the immunosuppressive enzyme indoleamine 2,3-dioxygenase 1 (IDO1): Probing the active site-inhibitor interactions.
    Tomek P; Palmer BD; Flanagan JU; Sun C; Raven EL; Ching LM
    Eur J Med Chem; 2017 Jan; 126():983-996. PubMed ID: 28011425
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 4,6-Substituted-1H-Indazoles as potent IDO1/TDO dual inhibitors.
    Yang L; Chen Y; He J; Njoya EM; Chen J; Liu S; Xie C; Huang W; Wang F; Wang Z; Li Y; Qian S
    Bioorg Med Chem; 2019 Mar; 27(6):1087-1098. PubMed ID: 30773421
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 4,5-Disubstituted 1,2,3-triazoles: Effective Inhibition of Indoleamine 2,3-Dioxygenase 1 Enzyme Regulates T cell Activity and Mitigates Tumor Growth.
    Panda S; Pradhan N; Chatterjee S; Morla S; Saha A; Roy A; Kumar S; Bhattacharyya A; Manna D
    Sci Rep; 2019 Dec; 9(1):18455. PubMed ID: 31804586
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO).
    Pan S; Zhou Y; Wang Q; Wang Y; Tian C; Wang T; Huang L; Nan J; Li L; Yang S
    Eur J Med Chem; 2020 Dec; 207():112703. PubMed ID: 32871341
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In silico discovery and therapeutic potential of IDO1 and TDO2 inhibitors.
    Jernigan FE; Sun L
    Future Med Chem; 2017 Aug; 9(12):1309-1311. PubMed ID: 28771034
    [No Abstract]   [Full Text] [Related]  

  • 14. High-throughput fluorescence-based screening assays for tryptophan-catabolizing enzymes.
    Seegers N; van Doornmalen AM; Uitdehaag JC; de Man J; Buijsman RC; Zaman GJ
    J Biomol Screen; 2014 Oct; 19(9):1266-74. PubMed ID: 24870017
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors.
    Meininger D; Zalameda L; Liu Y; Stepan LP; Borges L; McCarter JD; Sutherland CL
    Biochim Biophys Acta; 2011 Dec; 1814(12):1947-54. PubMed ID: 21835273
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.
    Röhrig UF; Majjigapu SR; Chambon M; Bron S; Pilotte L; Colau D; Van den Eynde BJ; Turcatti G; Vogel P; Zoete V; Michielin O
    Eur J Med Chem; 2014 Sep; 84():284-301. PubMed ID: 25036789
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of novel IDO1 inhibitors via structure-based virtual screening and biological assays.
    Ge H; Mao L; Zhao J; Wang Y; Shi D; Yang X; Wang X; Liu H; Yao X
    J Comput Aided Mol Des; 2021 May; 35(5):679-694. PubMed ID: 33905074
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
    Bakmiwewa SM; Fatokun AA; Tran A; Payne RJ; Hunt NH; Ball HJ
    Bioorg Med Chem Lett; 2012 Dec; 22(24):7641-6. PubMed ID: 23122865
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of cyanopyridine scaffold as novel indoleamine-2,3-dioxygenase 1 (IDO1) inhibitors through virtual screening and preliminary hit optimisation.
    Xu X; Ren J; Ma Y; Liu H; Rong Q; Feng Y; Wang Y; Cheng Y; Ge R; Li Z; Bian J
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):250-263. PubMed ID: 30734612
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, Synthesis and Biological Evaluation of Novel 1,2,5-Oxadiazol-3- Carboximidamide Derivatives as Indoleamine 2, 3-Dioxygenase 1 (IDO1) Inhibitors.
    Xia Z; Nan Y; Liu C; Lin G; Gu K; Chen C; Zhao W; Ju D; Dong X
    Anticancer Agents Med Chem; 2020; 20(13):1592-1603. PubMed ID: 32496990
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.