BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1044 related articles for article (PubMed ID: 31198958)

  • 1. Developing Heritable Mutations in Arabidopsis thaliana Using a Modified CRISPR/Cas9 Toolkit Comprising PAM-Altered Cas9 Variants and gRNAs.
    Yamamoto A; Ishida T; Yoshimura M; Kimura Y; Sawa S
    Plant Cell Physiol; 2019 Oct; 60(10):2255-2262. PubMed ID: 31198958
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
    Chen W; Zhang H; Zhang Y; Wang Y; Gan J; Ji Q
    PLoS Biol; 2019 Oct; 17(10):e3000496. PubMed ID: 31603896
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9.
    Hirano S; Nishimasu H; Ishitani R; Nureki O
    Mol Cell; 2016 Mar; 61(6):886-94. PubMed ID: 26990991
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Cas9 protein variant VQR recognizes NGAC protospacer adjacent motif in rice].
    Xin GW; Hu XX; Wang KJ; Wang XC
    Yi Chuan; 2018 Dec; 40(12):1112-1119. PubMed ID: 30559100
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
    Kleinstiver BP; Prew MS; Tsai SQ; Topkar VV; Nguyen NT; Zheng Z; Gonzales AP; Li Z; Peterson RT; Yeh JR; Aryee MJ; Joung JK
    Nature; 2015 Jul; 523(7561):481-5. PubMed ID: 26098369
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantification of the affinities of CRISPR-Cas9 nucleases for cognate protospacer adjacent motif (PAM) sequences.
    Mekler V; Kuznedelov K; Severinov K
    J Biol Chem; 2020 May; 295(19):6509-6517. PubMed ID: 32241913
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genome editing in plants by engineered CRISPR-Cas9 recognizing NG PAM.
    Endo M; Mikami M; Endo A; Kaya H; Itoh T; Nishimasu H; Nureki O; Toki S
    Nat Plants; 2019 Jan; 5(1):14-17. PubMed ID: 30531939
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural insights into a high fidelity variant of SpCas9.
    Guo M; Ren K; Zhu Y; Tang Z; Wang Y; Zhang B; Huang Z
    Cell Res; 2019 Mar; 29(3):183-192. PubMed ID: 30664728
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genome Editing in Zebrafish by ScCas9 Recognizing NNG PAM.
    Liu Y; Liang F; Dong Z; Li S; Ye J; Qin W
    Cells; 2021 Aug; 10(8):. PubMed ID: 34440868
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expanding the scope of CRISPR/Cas9-mediated genome editing in plants using an xCas9 and Cas9-NG hybrid.
    Niu Q; Wu S; Li Y; Yang X; Liu P; Xu Y; Lang Z
    J Integr Plant Biol; 2020 Apr; 62(4):398-402. PubMed ID: 31702097
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In Planta Processing of the SpCas9-gRNA Complex.
    Mikami M; Toki S; Endo M
    Plant Cell Physiol; 2017 Nov; 58(11):1857-1867. PubMed ID: 29040704
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular Mechanism of D1135E-Induced Discriminated CRISPR-Cas9 PAM Recognition.
    Kang M; Zuo Z; Yin Z; Gu J
    J Chem Inf Model; 2022 Jun; 62(12):3057-3066. PubMed ID: 35666156
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genome Engineering in Rice Using Cas9 Variants that Recognize NG PAM Sequences.
    Hua K; Tao X; Han P; Wang R; Zhu JK
    Mol Plant; 2019 Jul; 12(7):1003-1014. PubMed ID: 30928636
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increasing the efficiency of CRISPR-Cas9-VQR precise genome editing in rice.
    Hu X; Meng X; Liu Q; Li J; Wang K
    Plant Biotechnol J; 2018 Jan; 16(1):292-297. PubMed ID: 28605576
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Improving Plant Genome Editing with High-Fidelity xCas9 and Non-canonical PAM-Targeting Cas9-NG.
    Zhong Z; Sretenovic S; Ren Q; Yang L; Bao Y; Qi C; Yuan M; He Y; Liu S; Liu X; Wang J; Huang L; Wang Y; Baby D; Wang D; Zhang T; Qi Y; Zhang Y
    Mol Plant; 2019 Jul; 12(7):1027-1036. PubMed ID: 30928637
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
    Anders C; Bargsten K; Jinek M
    Mol Cell; 2016 Mar; 61(6):895-902. PubMed ID: 26990992
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Superior Fidelity and Distinct Editing Outcomes of SaCas9 Compared with SpCas9 in Genome Editing.
    Yang ZX; Fu YW; Zhao JJ; Zhang F; Li SA; Zhao M; Wen W; Zhang L; Cheng T; Zhang JP; Zhang XB
    Genomics Proteomics Bioinformatics; 2023 Dec; 21(6):1206-1220. PubMed ID: 36549468
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Structure-based optimization and design of CRISPR protein xCas9].
    Xue D; Zhu H; Du W; Tang H; Huang Q
    Sheng Wu Gong Cheng Xue Bao; 2021 Apr; 37(4):1385-1395. PubMed ID: 33973451
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The SpRY Cas9 variant release the PAM sequence constraint for genome editing in the model plant Physcomitrium patens.
    Calbry J; Goudounet G; Charlot F; Guyon-Debast A; Perroud PF; Nogué F
    Transgenic Res; 2024 Apr; 33(1-2):67-74. PubMed ID: 38573428
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genome editing mediated by SpCas9 variants with broad non-canonical PAM compatibility in plants.
    Li J; Xu R; Qin R; Liu X; Kong F; Wei P
    Mol Plant; 2021 Feb; 14(2):352-360. PubMed ID: 33383203
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 53.