BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 31200864)

  • 1. Ligand-induced genetic degradation as a tool for target validation.
    Yesbolatova A; Tominari Y; Kanemaki MT
    Drug Discov Today Technol; 2019 Apr; 31():91-98. PubMed ID: 31200864
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A small-molecule degron with a phenylpropionic acid scaffold.
    Tomoshige S; Komatsu F; Kikuchi T; Sugiyama M; Kawasaki Y; Ohgane K; Furuyama Y; Sato S; Ishikawa M; Kuramochi K
    Bioorg Med Chem; 2024 Jun; 109():117789. PubMed ID: 38870716
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proteolysis-targeting chimeras mediate the degradation of bromodomain and extra-terminal domain proteins.
    Yang Y; Wu Z; Chen P; Zheng P; Zhang H; Zhou J
    Future Med Chem; 2020 Sep; 12(18):1669-1683. PubMed ID: 32893690
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High throughput E3 ligase degron binding assays for novel PROTAC ligand discovery.
    Guenette RG; Potts PR
    Methods Enzymol; 2023; 681():23-39. PubMed ID: 36764759
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ligand-induced degrons for studying nuclear functions.
    Kanemaki MT
    Curr Opin Cell Biol; 2022 Feb; 74():29-36. PubMed ID: 35065444
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PROTACs: An Emerging Targeting Technique for Protein Degradation in Drug Discovery.
    Gu S; Cui D; Chen X; Xiong X; Zhao Y
    Bioessays; 2018 Apr; 40(4):e1700247. PubMed ID: 29473971
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeted protein degradation and drug discovery.
    Naito M
    J Biochem; 2022 Jul; 172(2):61-69. PubMed ID: 35468190
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proteolysis-targeting chimeras for targeting protein for degradation.
    Qi J; Zhang G
    Future Med Chem; 2019 Apr; 11(7):723-741. PubMed ID: 30706727
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting Cancer Cells via N-degron-based PROTACs.
    Eldeeb MA; Zorca CE; Fahlman RP
    Endocrinology; 2020 Dec; 161(12):. PubMed ID: 33159513
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeted protein degradation: Emerging concepts and protein state-specific targeting principles.
    Tao AJ; Gadbois GE; Buczynski SA; Ferguson FM
    Curr Opin Chem Biol; 2022 Apr; 67():102114. PubMed ID: 35042023
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeted Protein Degradation Tools: Overview and Future Perspectives.
    Prozzillo Y; Fattorini G; Santopietro MV; Suglia L; Ruggiero A; Ferreri D; Messina G
    Biology (Basel); 2020 Nov; 9(12):. PubMed ID: 33256092
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two-Stage Strategy for Development of Proteolysis Targeting Chimeras and its Application for Estrogen Receptor Degraders.
    Roberts BL; Ma ZX; Gao A; Leisten ED; Yin D; Xu W; Tang W
    ACS Chem Biol; 2020 Jun; 15(6):1487-1496. PubMed ID: 32255606
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Generation of conditional auxin-inducible degron (AID) cells and tight control of degron-fused proteins using the degradation inhibitor auxinole.
    Yesbolatova A; Natsume T; Hayashi KI; Kanemaki MT
    Methods; 2019 Jul; 164-165():73-80. PubMed ID: 31026591
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Small molecule PROTACs in targeted therapy: An emerging strategy to induce protein degradation.
    Xi M; Chen Y; Yang H; Xu H; Du K; Wu C; Xu Y; Deng L; Luo X; Yu L; Wu Y; Gao X; Cai T; Chen B; Shen R; Sun H
    Eur J Med Chem; 2019 Jul; 174():159-180. PubMed ID: 31035238
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluating Ligands for Ubiquitin Ligases Using Affinity Beads.
    Dobrodziej J; Dong H; Zimmermann K; Hickey CM
    Methods Mol Biol; 2021; 2365():59-75. PubMed ID: 34432239
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The importance of cellular degradation kinetics for understanding mechanisms in targeted protein degradation.
    Riching KM; Caine EA; Urh M; Daniels DL
    Chem Soc Rev; 2022 Jul; 51(14):6210-6221. PubMed ID: 35792307
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeted Protein Depletion Using the Auxin-Inducible Degron 2 (AID2) System.
    Saito Y; Kanemaki MT
    Curr Protoc; 2021 Aug; 1(8):e219. PubMed ID: 34370399
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Efficient, multi-hundred-gram scale access to E3 ubiquitin ligase ligands for degrader development.
    Cooper MS; Norley MC; Armitage S; Cresser-Brown JO; Edmonds AK; Goggins S; Hopewell JP; Karadogan B; Knights KA; Nash TJ; Oakes CS; O'Neill WJ; Pridmore SJ; Maple HJ; Marsh GP
    Org Biomol Chem; 2023 Oct; 21(41):8344-8352. PubMed ID: 37800999
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Major Advances in Emerging Degrader Technologies.
    Luo H; Wu L; He Y; Qin C; Tang X
    Front Cell Dev Biol; 2022; 10():921958. PubMed ID: 35813205
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Present and Future of Novel Protein Degradation Technology.
    Xia L; Liu W; Song Y; Zhu H; Duan Y
    Curr Top Med Chem; 2019; 19(20):1784-1788. PubMed ID: 31644408
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.