BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 31204230)

  • 1. Identification of topoisomerases as molecular targets of cytosporolide C and its analog.
    Otake K; Yamada K; Miura K; Sasazawa Y; Miyazaki S; Niwa Y; Ogura A; Takao KI; Simizu S
    Bioorg Med Chem; 2019 Aug; 27(15):3334-3338. PubMed ID: 31204230
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of new halogen-containing 2,4-diphenyl indenopyridin-5-one derivative as a boosting agent for the anticancer responses of clinically available topoisomerase inhibitors.
    Hwang SY; Shrestha A; Park S; Bist G; Kunwar S; Kadayat TM; Jang H; Seo M; Sheen N; Kim S; Jeon KH; Lee ES; Kwon Y
    Eur J Med Chem; 2022 Jan; 227():113916. PubMed ID: 34678573
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors.
    Arepalli SK; Lee C; Sim S; Lee K; Jo H; Jun KY; Kwon Y; Kang JS; Jung JK; Lee H
    Bioorg Med Chem; 2018 Oct; 26(18):5181-5193. PubMed ID: 30253887
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A new phenolic series of indenopyridinone as topoisomerase inhibitors: Design, synthesis, and structure-activity relationships.
    Shrestha A; Park S; Jang HJ; Katila P; Shrestha R; Kwon Y; Lee ES
    Bioorg Med Chem; 2018 Oct; 26(18):5212-5223. PubMed ID: 30262132
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, anticancer evaluation and molecular docking studies of new heterocycles linked to sulfonamide moiety as novel human topoisomerase types I and II poisons.
    Halawa AH; Elgammal WE; Hassan SM; Hassan AH; Nassar HS; Ebrahim HY; Mehany ABM; El-Agrody AM
    Bioorg Chem; 2020 May; 98():103725. PubMed ID: 32199303
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure-activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor.
    Ahmad P; Woo H; Jun KY; Kadi AA; Abdel-Aziz HA; Kwon Y; Rahman AF
    Bioorg Med Chem; 2016 Apr; 24(8):1898-908. PubMed ID: 26988802
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Topoisomerase Inhibitors and Targeted Delivery in Cancer Therapy.
    You F; Gao C
    Curr Top Med Chem; 2019; 19(9):713-729. PubMed ID: 30931860
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of Novel Pyrazole Derivatives as Promising DNA-Binding Agents and Evaluation of Antitumor and Antitopoisomerases I/II Activities.
    Feng J; Qi H; Sun X; Feng S; Liu Z; Song Y; Qiao X
    Chem Pharm Bull (Tokyo); 2018 Nov; 66(11):1065-1071. PubMed ID: 30197406
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors.
    Wu WB; Ou JB; Huang ZH; Chen SB; Ou TM; Tan JH; Li D; Shen LL; Huang SL; Gu LQ; Huang ZS
    Eur J Med Chem; 2011 Aug; 46(8):3339-47. PubMed ID: 21600681
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, Biological Evaluation and Molecular Docking Study of Cyclic Diarylheptanoids as Potential Anticancer Therapeutics.
    Lu Y; Yin W; Alam MS; Kadi AA; Jahng Y; Kwon Y; Rahman AFMM
    Anticancer Agents Med Chem; 2020; 20(4):464-475. PubMed ID: 31763968
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 11-Substituted Benzo[c]phenanthridines: New Structures and Insight into Their Mode of Antiproliferative Action.
    Clement B; Girreser U; Steinhauer TN; Meier C; Marko D; Aichinger G; Kaltefleiter I; Stenzel L; Heber D; Weide M; Wolschendorf U; Zebothsen I; Zur Nieden D
    ChemMedChem; 2016 Oct; 11(19):2155-2170. PubMed ID: 27546098
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel urea linked ciprofloxacin-chalcone hybrids having antiproliferative topoisomerases I/II inhibitory activities and caspases-mediated apoptosis.
    Mohammed HHH; Abbas SH; Hayallah AM; Abuo-Rahma GEA; Mostafa YA
    Bioorg Chem; 2021 Jan; 106():104422. PubMed ID: 33248713
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tacrine-Coumarin Derivatives as Topoisomerase Inhibitors with Antitumor Effects on A549 Human Lung Carcinoma Cancer Cell Lines.
    Konkoľová E; Hudáčová M; Hamuľaková S; Jendželovský R; Vargová J; Ševc J; Fedoročko P; Kožurková M
    Molecules; 2021 Feb; 26(4):. PubMed ID: 33672694
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and evaluation of new antitumor 3-aminomethyl-4,11-dihydroxynaphtho[2,3-f]indole-5,10-diones.
    Shchekotikhin AE; Glazunova VA; Dezhenkova LG; Luzikov YN; Buyanov VN; Treshalina HM; Lesnaya NA; Romanenko VI; Kaluzhny DN; Balzarini J; Agama K; Pommier Y; Shtil AA; Preobrazhenskaya MN
    Eur J Med Chem; 2014 Oct; 86():797-805. PubMed ID: 25244612
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 2-Chlorophenyl-substituted benzofuro[3,2-b]pyridines with enhanced topoisomerase inhibitory activity: The role of the chlorine substituent.
    Thapa Magar TB; Kadayat TM; Lee HJ; Park S; Bist G; Shrestha A; Kwon Y; Lee ES
    Bioorg Med Chem Lett; 2017 Aug; 27(15):3279-3283. PubMed ID: 28633898
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N-2-(phenylamino) benzamide derivatives as novel anti-glioblastoma agents: Synthesis and biological evaluation.
    Li J; Hu X; Luo T; Lu Y; Feng Y; Zhang H; Liu D; Fan X; Wang Y; Jiang L; Wang Y; Hao X; Shi T; Wang Z
    Eur J Med Chem; 2021 Dec; 226():113817. PubMed ID: 34537445
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and topoisomerases inhibitory activity of heteroaromatic chalcones.
    Jeon KH; Yu HB; Kwak SY; Kwon Y; Na Y
    Bioorg Med Chem; 2016 Nov; 24(22):5921-5928. PubMed ID: 27707625
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and structure-activity relationships of hydroxylated and halogenated 2,4-diaryl benzofuro[3,2-b]pyridin-7-ols as selective topoisomerase IIα inhibitors.
    Thapa Magar TB; Hee Seo S; Shrestha A; Kim JA; Kunwar S; Bist G; Kwon Y; Lee ES
    Bioorg Chem; 2021 Jun; 111():104884. PubMed ID: 33872925
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A series of novel terpyridine-skeleton molecule derivants inhibit tumor growth and metastasis by targeting topoisomerases.
    Kwon HB; Park C; Jeon KH; Lee E; Park SE; Jun KY; Kadayat TM; Thapa P; Karki R; Na Y; Park MS; Rho SB; Lee ES; Kwon Y
    J Med Chem; 2015 Feb; 58(3):1100-22. PubMed ID: 25603122
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and anticancer evaluation of acridine hydroxamic acid derivatives as dual Topo and HDAC inhibitors.
    Chen J; Li D; Li W; Yin J; Zhang Y; Yuan Z; Gao C; Liu F; Jiang Y
    Bioorg Med Chem; 2018 Aug; 26(14):3958-3966. PubMed ID: 29954683
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.