These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 31208525)

  • 1. Dichloroacetate-induced peripheral neuropathy.
    Stacpoole PW; Martyniuk CJ; James MO; Calcutt NA
    Int Rev Neurobiol; 2019; 145():211-238. PubMed ID: 31208525
    [TBL] [Abstract][Full Text] [Related]  

  • 2.
    Tian DD; Bennett SK; Coupland LA; Forwood K; Lwin Y; Pooryousef N; Tea I; Truong TT; Neeman T; Crispin P; D'Rozario J; Blackburn AC
    Pharmacol Res Perspect; 2019 Dec; 7(6):e00526. PubMed ID: 31624634
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Clinical pharmacology and toxicology of dichloroacetate.
    Stacpoole PW; Henderson GN; Yan Z; James MO
    Environ Health Perspect; 1998 Aug; 106 Suppl 4(Suppl 4):989-94. PubMed ID: 9703483
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Peripheral neuropathy in rats exposed to dichloroacetate.
    Calcutt NA; Lopez VL; Bautista AD; Mizisin LM; Torres BR; Shroads AL; Mizisin AP; Stacpoole PW
    J Neuropathol Exp Neurol; 2009 Sep; 68(9):985-93. PubMed ID: 19680144
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dichloroacetate toxicokinetics and disruption of tyrosine catabolism in B6C3F1 mice: dose-response relationships and age as a modifying factor.
    Schultz IR; Merdink JL; Gonzalez-Leon A; Bull RJ
    Toxicology; 2002 May; 173(3):229-47. PubMed ID: 11960676
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1.
    James MO; Jahn SC; Zhong G; Smeltz MG; Hu Z; Stacpoole PW
    Pharmacol Ther; 2017 Feb; 170():166-180. PubMed ID: 27771434
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The pharmacology of dichloroacetate.
    Stacpoole PW
    Metabolism; 1989 Nov; 38(11):1124-44. PubMed ID: 2554095
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Age-dependent kinetics and metabolism of dichloroacetate: possible relevance to toxicity.
    Shroads AL; Guo X; Dixit V; Liu HP; James MO; Stacpoole PW
    J Pharmacol Exp Ther; 2008 Mar; 324(3):1163-71. PubMed ID: 18096758
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exposure of Rats to Multiple Oral Doses of Dichloroacetate Results in Upregulation of Hepatic Glutathione Transferases and NAD(P)H Dehydrogenase [Quinone] 1.
    Squirewell EJ; Mareus R; Horne LP; Stacpoole PW; James MO
    Drug Metab Dispos; 2020 Nov; 48(11):1224-1230. PubMed ID: 32873592
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats.
    Squirewell EJ; Smeltz MG; Rowland-Faux L; Horne LP; Stacpoole PW; James MO
    Drug Metab Dispos; 2020 Nov; 48(11):1217-1223. PubMed ID: 32873593
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The dichloroacetate dilemma: environmental hazard versus therapeutic goldmine--both or neither?
    Stacpoole PW
    Environ Health Perspect; 2011 Feb; 119(2):155-8. PubMed ID: 20920954
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Effects of Sodium Dichloroacetate on Mitochondrial Dysfunction and Neuronal Death Following Hypoglycemia-Induced Injury.
    Kho AR; Choi BY; Lee SH; Hong DK; Jeong JH; Kang BS; Kang DH; Park KH; Park JB; Suh SW
    Cells; 2019 May; 8(5):. PubMed ID: 31052436
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dichloroacetate and Pyruvate Metabolism: Pyruvate Dehydrogenase Kinases as Targets Worth Investigating for Effective Therapy of Toxoplasmosis.
    Ferrarini MG; Nisimura LM; Girard RMBM; Alencar MB; Fragoso MSI; Araújo-Silva CA; Veiga AA; Abud APR; Nardelli SC; Vommaro RC; Silber AM; France-Sagot M; Ávila AR
    mSphere; 2021 Jan; 6(1):. PubMed ID: 33408226
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting of two aspects of metabolism in breast cancer treatment.
    Gang BP; Dilda PJ; Hogg PJ; Blackburn AC
    Cancer Biol Ther; 2014; 15(11):1533-41. PubMed ID: 25482950
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition and recovery of rat hepatic glutathione S-transferase zeta and alteration of tyrosine metabolism following dichloroacetate exposure and withdrawal.
    Guo X; Dixit V; Liu H; Shroads AL; Henderson GN; James MO; Stacpoole PW
    Drug Metab Dispos; 2006 Jan; 34(1):36-42. PubMed ID: 16199472
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage differentiation.
    Kumar A; Kant S; Singh SM
    Toxicol Appl Pharmacol; 2013 Nov; 273(1):196-208. PubMed ID: 24051182
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pyruvate dehydrogenase kinase expression and metabolic changes following dichloroacetate exposure in anoxic human colorectal cancer cells.
    Ho N; Coomber BL
    Exp Cell Res; 2015 Feb; 331(1):73-81. PubMed ID: 25536473
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dichloroacetate and cancer: new home for an orphan drug?
    Kankotia S; Stacpoole PW
    Biochim Biophys Acta; 2014 Dec; 1846(2):617-29. PubMed ID: 25157892
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer.
    Stacpoole PW
    J Natl Cancer Inst; 2017 Nov; 109(11):. PubMed ID: 29059435
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetate.
    Li J; Kato M; Chuang DT
    J Biol Chem; 2009 Dec; 284(49):34458-67. PubMed ID: 19833728
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.