BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

303 related articles for article (PubMed ID: 31209037)

  • 1. An ATR and CHK1 kinase signaling mechanism that limits origin firing during unperturbed DNA replication.
    Moiseeva TN; Yin Y; Calderon MJ; Qian C; Schamus-Haynes S; Sugitani N; Osmanbeyoglu HU; Rothenberg E; Watkins SC; Bakkenist CJ
    Proc Natl Acad Sci U S A; 2019 Jul; 116(27):13374-13383. PubMed ID: 31209037
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dormant origin signaling during unperturbed replication.
    Moiseeva TN; Bakkenist CJ
    DNA Repair (Amst); 2019 Sep; 81():102655. PubMed ID: 31311769
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1.
    Alver RC; Chadha GS; Gillespie PJ; Blow JJ
    Cell Rep; 2017 Mar; 18(10):2508-2520. PubMed ID: 28273463
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1.
    Moiseeva T; Hood B; Schamus S; O'Connor MJ; Conrads TP; Bakkenist CJ
    Nat Commun; 2017 Nov; 8(1):1392. PubMed ID: 29123096
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human CTC1 promotes TopBP1 stability and CHK1 phosphorylation in response to telomere dysfunction and global replication stress.
    Ackerson SM; Gable CI; Stewart JA
    Cell Cycle; 2020 Dec; 19(24):3491-3507. PubMed ID: 33269665
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of ATR-CHK1 signaling by ubiquitination of CLASPIN.
    Zhu X; Zheng XY; Gong P; Xu X
    Biochem Soc Trans; 2022 Oct; 50(5):1471-1480. PubMed ID: 36196914
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ATR and ATM regulate the timing of DNA replication origin firing.
    Shechter D; Costanzo V; Gautier J
    Nat Cell Biol; 2004 Jul; 6(7):648-55. PubMed ID: 15220931
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories.
    Ge XQ; Blow JJ
    J Cell Biol; 2010 Dec; 191(7):1285-97. PubMed ID: 21173116
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Marek's Disease Virus Disables the ATR-Chk1 Pathway by Activating STAT3.
    Lian X; Bao C; Li X; Zhang X; Chen H; Jung YS; Qian Y
    J Virol; 2019 May; 93(9):. PubMed ID: 30787154
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress.
    Yamada M; Watanabe K; Mistrik M; Vesela E; Protivankova I; Mailand N; Lee M; Masai H; Lukas J; Bartek J
    Genes Dev; 2013 Nov; 27(22):2459-72. PubMed ID: 24240236
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATR-Chk1 activation mitigates replication stress caused by mismatch repair-dependent processing of DNA damage.
    Gupta D; Lin B; Cowan A; Heinen CD
    Proc Natl Acad Sci U S A; 2018 Feb; 115(7):1523-1528. PubMed ID: 29378956
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of the ATR-CHK1 Pathway in Ewing Sarcoma Cells Causes DNA Damage and Apoptosis via the CDK2-Mediated Degradation of RRM2.
    Koppenhafer SL; Goss KL; Terry WW; Gordon DJ
    Mol Cancer Res; 2020 Jan; 18(1):91-104. PubMed ID: 31649026
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response.
    Lin YF; Shih HY; Shang Z; Matsunaga S; Chen BP
    Nucleic Acids Res; 2014 Apr; 42(7):4463-73. PubMed ID: 24500207
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An extending ATR-CHK1 circuitry: the replication stress response and beyond.
    Simoneau A; Zou L
    Curr Opin Genet Dev; 2021 Dec; 71():92-98. PubMed ID: 34329853
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer.
    Liu K; Graves JD; Lin FT; Lin WC
    J Biol Chem; 2021; 296():100382. PubMed ID: 33556369
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of ATR-dependent feedback activation of Chk1 sensitises cancer cells to Chk1 inhibitor monotherapy.
    Massey AJ
    Cancer Lett; 2016 Dec; 383(1):41-52. PubMed ID: 27693461
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insulin-like Growth Factor 1 Receptor Signaling Is Required for Optimal ATR-CHK1 Kinase Signaling in Ultraviolet B (UVB)-irradiated Human Keratinocytes.
    Kemp MG; Spandau DF; Simman R; Travers JB
    J Biol Chem; 2017 Jan; 292(4):1231-1239. PubMed ID: 27979966
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ATR kinase regulates its attenuation via PPM1D phosphatase recruitment to chromatin during recovery from DNA replication stress signalling.
    Bhattacharya D; Hiregange D; Rao BJ
    J Biosci; 2018 Mar; 43(1):25-47. PubMed ID: 29485113
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intra-S phase checkpoint kinase Chk1 dissociates replication proteins Treslin and TopBP1 through multiple mechanisms during replication stress.
    Kelly RL; Huehls AM; Venkatachalam A; Huntoon CJ; Machida YJ; Karnitz LM
    J Biol Chem; 2022 Apr; 298(4):101777. PubMed ID: 35231445
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence that the ATR/Chk1 pathway maintains normal replication fork progression during unperturbed S phase.
    Petermann E; Caldecott KW
    Cell Cycle; 2006 Oct; 5(19):2203-9. PubMed ID: 16969104
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.